Metastatic Serous Carcinoma Initially Presented As An Incarcerated And Strangulated Umbilical Hernia: A Rare Case Report

Introduction: We report a rare case of a metastatic serous ovarian carcinoma presented as an incarcerated and strangulated umbilical hernia.Presentation of case: A 54 year-old female was admitted to the hospital with a painful mass around the umblical region. It was elucidated during clinical history that the mass had been present for 3 to 4 years without pain. An incarcerated and strangulated umbilical hernia including a solid mass and mesenteric fat was detected on physical examination. She underwent an urgent operation for strangulated umbilical hernia. The pathological diagnosis of the hernia material was reported as carcinoma compatible with serous ovarian carcinoma metastasis. Concurrently, total abdominal histerectomy and bilateral salphingo-oopherectomy, pelvic and paraaortic lymph node dissection, omentectomy and sigmoid colon resection were performed. Histopathological evaluation confirmed the serous carcinoma originated from the left ovary.Conclusion: In the literature, some metastatic tumors have been reported to be presented as umbilical metastasis rarely. However, the present case is the first metastatic ovarian cancer that initially presented as an incarcerated and strangulated umbilical hernia in the literature, to the best of our knowledge. 

Evaluation of the i-STAT Blood Gas Analysis System in Cardiovascular Surgery

The aim of this study was toinvestigate the compatibility of the parameters measured with the i-STAT blood gas analyser and the conventional blood gas analyser Rapid Point 500 (Siemens Healthcare Diagnostics, USA) in patients who underwent cardiovascular surgery. This clinical study included fifty patients undergoing coronary artery bypass surgery. Fifty whole blood samples were portioned and measured on the i-STAT and RP500 laboratory analyzers. The compatibility between pH, pCO2, pO2, Hb, Na+, K+, iCa2+ and glucose values was investigated.There was a good correlation of the i-STAT analyser with the RP500 analyser, with the exception Hb and Na+. Also all parameters except for Hb and ionized calcium were found to be within acceptable range in terms of clinical decision limits. It is very important that the point-of-care devices give accurate results as well as quick results. For this reason, we absolutely think that the point of care devices should be subjected to external and internal quality control programs, users should be trained regularly and feedback studies should be done

Interview with Marjorie Harkins Buchanan Kiewit

In this interview with Julia Stringfellow, Marjorie Harkins Buchanan Kiewit, LU class of 1943, discusses her time as a student as well as her time on the Board of Trustees.https://lux.lawrence.edu/oralhistories/1036/thumbnail.jp

Inlet patch mimicking unstable angina pectoris

The ectopic stomach mucosa island in the proximal esophagus, which is generally known as the inlet patch or cervical inlet patch, is called as the heterotopic gastric mucosa of the esophagus. Despite its asymptomatic progress, it may cause chest pain, shortness of breath and difficulty in swallowing due to the acid secretion from the ectopic mucosa. The study aimed to present a patient who underwent coronary angiography with an unstable angina pectoris diagnosis by cardiologists for gastric chest pain but found an inlet patch in gastroduodenoscopy

Effect of Hyoscine-n-Butylbromide on Multimodal Analgesia for Laparoscopic Sleeve Gastrectomy: A Retrospective Case-Control Study

Background: Nonsteroidal anti-inflammatory drugs are commonly used in addition to opioids after laparoscopic sleeve gastrectomy (LSG). The aim of this study was to demonstrate the analgesic effect of hyoscine-n-butylbromide, a spasmolytic agent, in addition to different analgesic protocols. Methods: Postoperative analgesia records of 134 patients who underwent LSG were analyzed. Patients were divided into four groups according to additional analgesics used. Paracetamol (Group 1, n = 33), dexketoprofen trometamol (Group 2, n = 34), paracetamol and hyocine-n-butylbromide (Group 3, n = 32), and dexketoprofen trometamol and hyocine-n-butylbromide (Group 4, n = 35). The method of analgesia, the visual analogue scale (VAS), the applied analgesic doses, and patient satisfaction scores and side effects were recorded. Results: The cumulative opioid consumption in Group 1 (352.03 +/- 60.02 mg) was higher than that of Group 2 (291.73 +/- 53.70 mg), Group 3 (186.81 +/- 45.55 mg), and Group 4 (186.51 +/- 46.78 mg) (p < 0.05). In addition, in Group 2 the consumption was higher than that of Groups 3 and 4 (p < 0.05). The patient satisfaction score was lower in Groups 1 and 2 than that of Groups 3 and 4, respectively (p < 0.001). VAS scores for Groups 1 and 2 were higher than that of Groups 3 and 4 (p < 0.001). Conclusion: Addition of hyoscine-n-butylbromide to analgesic protocols improves postoperative patient comfort, decreases VAS scores and opioid consumption in LSG

Version française de la Turba Philosophorum : Paulette Duval, La Turba Philosophorum Gallica, Cahiers de Fontenay (5, rue Boucicaut, 92260 Fontenay-aux-Roses), n° 33, déc. 1983

Ardry Robert. Version française de la Turba Philosophorum : Paulette Duval, La Turba Philosophorum Gallica, Cahiers de Fontenay (5, rue Boucicaut, 92260 Fontenay-aux-Roses), n° 33, déc. 1983. In: Revue d'histoire de la pharmacie, 73ᵉ année, n°264, 1985. pp. 76-77