Outcome of gastroplasty and gastric bypass in a single centre in the UK

<p>Abstract</p> <p>Background</p> <p>Morbid obesity is defined as BMI>40 kg/m². It affects 124,000 men and 412,000 women in England and Wales (NICE, July 2002). According to NICE guidelines, Bariatric surgery is indicated if the treatments for obesity such as exercise, diet and drugs fail. Procedures include laparoscopic gastric banding (LGB), vertical banded gastroplasty (VBG), and Gastric Bypass (GB).</p> <p>Aims</p> <p>The aim of this audit was to determine if NICE guidelines on the use of Bariatric surgery in the Manor Hospital, Walsall was being adhered to. <b>Secondary aims were </b>also to establish if Bariatric surgery is achieving its goal in the long-term and if weight reduction is being maintained in this group of patients.</p> <p>Methods</p> <p>A retrospective cohort study was carried out on patients who underwent Bariatric surgery between 1990 and 2004. Retrieved records were scrutinised and the following parameters were collated: pre-operative morbidities, intra and post-operative complication rates and weight reduction on follow-up.</p> <p>Results</p> <p>129 patients were operated on in the 14 year period. For VBG, 40 out of 105 patients had weight gain by the 5th follow-up visit. This compared with 5 out of 18 patients after the same timescale for the GB group and 1 out of 6 in the LGB group. The most common post-operative complication was stenosis (28% of VBG group).</p> <p>Conclusion</p> <p>Bariatric surgery is relatively safe as an intervention for morbid obesity. Weight loss however is not maintained in the long term. VBG and LGB are short term interventions. Further research is required to look into the merits of gastric bypass surgery.</p

A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)

Patients with cancer are at increased risk of hospitalisation and mortality following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV-2 phenotype evolution in patients with cancer since 2020 has not previously been described. We therefore evaluated SARS-CoV-2 on a UK populationscale from 01/11/2020-31/08/2022, assessing case-outcome rates of hospital assessment(s), intensive care admission and mortality. We observed that the SARS-CoV-2 disease phenotype has become less severe in patients with cancer and the non-cancer population. Case-hospitalisation rates for patients with cancer dropped from 30.58% in early 2021 to 7.45% in 2022 while case-mortality rates decreased from 20.53% to 3.25%. However, the risk of hospitalisation and mortality remains 2.10x and 2.54x higher in patients with cancer, respectively. Overall, the SARS-CoV-2 disease phenotype is less severe in 2022 compared to 2020 but patients with cancer remain at higher risk than the non-cancer population. Patients with cancer must therefore be empowered to live more normal lives, to see loved ones and families, while also being safeguarded with expanded measures to reduce the risk of transmission

The value of a joint cerebrovascular neurology clinic in carotid surgery practice

Objectives: The aims of the clinic were to offer suitable patients carotid endarterectomy with minimal delay, to discuss patients with unclear symptoms and to offer the best advice to patients referred with asymptomatic carotid artery stenosis. Design: A retrospective note review of all the patients who attended the clinic over a two-year period between January 1997 and December 1998 was undertaken. A pro-forma was completed. Participants: Three hundred and ninety-nine patients who were seen in the joint clinic for investigations of cerebrovascular disease. Main outcome measures: Waiting time for specialist consultations and treatment. Results: During that period 118 new patients and 281 follow-up patients were seen in the clinic. Colour flow Doppler was performed on 102 new patients and 113 follow-up patients. Digital Subtraction Angiography was used in selected patients (16). Sixty -six patients had combined consultations. Twenty-nine (24.6%) patients were assessed and discharged from the clinic on their first consultation. Seventy-three (62%) patients were listed for carotid endarterectomy. The mean waiting time from referral to consultation was 2.6 weeks and from consultation to surgical treatment was 4.7 weeks. Both these waiting times were significantly better than the waiting times before the joint cerebrovascular neurology clinic was set up. Conclusion: The combined clinic provided an appropriate environment for one-stop rapid assessment and treatment of patients with preventable stroke

Microtibial embolectomy.

AbstractBackground: microtibial embolectomy is an important technique in cases of limb threatening acute arterial occlusion affecting native crural and pedal vessels. It is particularly useful when thrombolysis is contraindicated or ineffective as in “trash foot”. Methods: in order to evaluate the efficacy of this technique, a retrospective case note review was carried out for patients undergoing microtibial embolectomy from 1990 to 1999. Data collected included the causes and degree of ischaemia, additional procedures required, vessel patency, limb salvage and complications encountered. Results: twenty-two limbs underwent exploration of the crural/pedal vessels with ankle level arteriotomies under local anaesthetic in 12 cases, general anaesthetic in nine and epidural in one. The causes of ischaemia were cardiac emboli (8), “trash foot” (7), emboli from aortic and popliteal aneurysms (3) and thrombotic occlusion of crural vessels (4). The vessel patency rate was 69% and limb salvage rate 62% (13/21) up to 5-years follow-up. Six of the seven cases with “trash foot” were salvaged while one required an amputation at 3-months post-operatively. The 30-day mortality was 22% (5/22). Conclusions: microtibial embolectomy is effective in acute occlusion of the crural/pedal arteries including cases of “trash foot”, offering limb salvage to a worthwhile proportion of cases.Eur J Vasc Endovasc Surg 25, 35–39 (2003