The mapping method as a toolbox to analyze, design, and optimize micromixers

The mapping method is employed as an efficient toolbox to analyze, design, and optimize micromixers. A new and simplified formulation of this technique is introduced here and applied to three micromixers: the staggered herringbone micromixer (SHM), the barrier-embedded micromixer (BEM), and the three-dimensional serpentine channel (3D-SC). The mapping method computes a distribution matrix that maps the color concentration distribution from inlet to outlet of a micromixer to characterize mixing in a quantitative way. Once the necessary distribution matrices are obtained, computations are fast and numerous layouts of the mixer are easily evaluated, resulting in an optimal design. This approach is demonstrated using the SHM and the BEM as typical examples. Mixing analysis in the 3D-SC illustrates that also complex flows, for example in the presence of back-flows, can be efficiently dealt with by using the new formulation of the mapping metho

ATP synthesis driven by a pH gradient imposed across the cell membranes of lipoic acid and unsaturated fatty acid auxotrophs of escherichia coli

L'edifici té el seu origen a principis del segle XIX.Primer pla, contrapicat, d'un edifici de planta baixa i quatre plantes pis. S'estructura segons eixos verticals amb tres obertures per planta que s'organitzen com a balconades en els dos primers pisos i com a balcons en els restants

Nitrogen mineralization dynamics of different valuable organic amendments commonly used in agriculture

Published online: 27 February 2016This is an open access article under the CC BY-NC-ND licenseSustainable agriculture requires the careful optimization of the use of organic amendments to improve soil fertility while minimizing any harmful environmental effects. To understand the events that occur in soil after the addition of different organic amendments, we evaluated the nitrogen (N) mineralization dynamics in soil after adding organic amendments, and evaluated changes in the microbial population. The four organic amendments were fresh dairy cattle manure, fresh white clover, vegetable, fruit, and yard waste compost, and poplar tree compost. The N mineralization potential of each organic amendment was determined by analyzing total mineral nitrogen during a 97-day laboratory incubation experiment. Soils amended with clover released 240 μg N g−1 soil during the 97-day incubation, more than twice as much as that released from soils amended with manure or composts (76–100 μg N g−1 soil). At the end of the incubation, the net N mineralization in clover-amended soils was 54%, more than five times higher than that in soils amended with composts or manure (4%–9%). Nitrogen was mineralized faster in clover-amended soil (1.056 μg N g−1 soil day−1) than in soil amended with composts (0.361–0.417 μg N g−1 soil day−1). The microbial biomass carbon content was higher in clover-amended soil than in the soils amended with manure or composts. We monitored changes in the microbial population in amended soils by a phospholipid fatty acid (PLFA) analysis. On day 97, there were higher concentrations of total PLFAs in soils with organic amendments (e.g., 14.41 nmol g−1 in clover-amended soil) than in control soil without amendments (9.84 nmol g−1). Bacteria (Gram-positive and Gram-negative), actinomycetes, and fungi were more abundant in clover-amended soils than soils amended with manure or composts. The N mineralization potential varied among the four organic amendments. Therefore, the timing of application and the type of organic amendment should be matched to the nutrient needs of the crop

Brave New World versus Island — Utopian and Dystopian Views on Psychopharmacology

Aldous Huxley’s Brave New World is a famous dystopia, frequently called upon in public discussions about new biotechnology. It is less well known that 30 years later Huxley also wrote a utopian novel, called Island. This paper will discuss both novels focussing especially on the role of psychopharmacological substances. If we see fiction as a way of imagining what the world could look like, then what can we learn from Huxley’s novels about psychopharmacology and how does that relate to the discussion in the ethical and philosophical literature on this subject? The paper argues that in the current ethical discussion the dystopian vision on psychopharmacology is dominant, but that a comparison between Brave New World and Island shows that a more utopian view is possible as well. This is illustrated by a discussion of the issue of psychopharmacology and authenticity. The second part of the paper draws some further conclusions for the ethical debate on psychopharmacology and human enhancement, by comparing the novels not only with each other, but also with our present reality. It is claimed that the debate should not get stuck in an opposition of dystopian and utopian views, but should address important issues that demand attention in our real world: those of evaluation and governance of enhancing psychopharmacological substances in democratic, pluralistic societies

Astrophysical constraints on primordial black holes in Brans-Dicke theory

We consider cosmological evolution in Brans-Dicke theory with a population of primordial black holes. Hawking radiation from the primordial black holes impacts various astrophysical processes during the evolution of the Universe. The accretion of radiation by the black holes in the radiation dominated era may be effective in imparting them a longer lifetime. We present a detailed study of how this affects various standard astrophysical constraints coming from the evaporation of primordial black holes. We analyze constraints from the present density of the Universe, the present photon spectrum, the distortion of the cosmic microwave background spectrum and also from processes affecting light element abundances after nucleosynthesis. We find that the constraints on the initial primordial black hole mass fractions are tightened with increased accretion efficiency.Comment: 15 page

First-principles Calculation of the Formation Energy in MgO-CaO Solid Solutions

The electronic structure and total energy were calculated for ordered and disordered MgO-CaO solid solutions within the multiple scattering theory in real space and the local density approximation. Based on the dependence of the total energy on the unit cell volume the equilibrium lattice parameter and formation energy were determined for different solution compositions. The formation energy of the solid solutions is found to be positive that is in agreement with the experimental phase diagram, which shows a miscibility gap.Comment: 11 pages, 3 figure

Spherically Symmetric Braneworld Solutions with R_{4} term in the Bulk

An analysis of a spherically symmetric braneworld configuration is performed when the intrinsic curvature scalar is included in the bulk action; the vanishing of the electric part of the Weyl tensor is used as the boundary condition for the embedding of the brane in the bulk. All the solutions outside a static localized matter distribution are found; some of them are of the Schwarzschild-(A)dS_{4} form. Two modified Oppenheimer-Volkoff interior solutions are also found; one is matched to a Schwarzschild-(A)dS_{4} exterior, while the other does not. A non-universal gravitational constant arises, depending on the density of the considered object; however, the conventional limits of the Newton's constant are recovered. An upper bound of the order of TeV for the energy string scale is extracted from the known solar system measurements (experiments). On the contrary, in usual brane dynamics, this string scale is calculated to be larger than TeV.Comment: 23 pages, 1 figure, one minor chang