127 research outputs found
Studentsâ perceptions of the Moodle Quiz E-assessment tool in an isiZulu language course
MOODLE, a free open source software, is the official Learning Management System (LMS) at the University of KwaZulu-Natal (UKZN). The institutionâs mandate to all academics to integrate Moodle into their respective disciplines for teaching and learning, created a space for the researchers to experiment with the Quiz tool as an alternate assessment method, as part of routine formative and summative assessments. Whilst there are many research studies that endorse e-assessments at tertiary institutions, this is an uncharted area of research within the field of teaching and learning of isiZulu in South Africa. As a result, there is a lack of empirical evidence to assist with curriculum integration and implementation thereof. The purpose of this study was to explore studentsâ perceptions and experiences on such integration and implementation of e-assessments. A questionnaire was administered to sixty first year Bachelor of Medicine and Bachelor of Surgery (MBChB) students enrolled for isiZulu. Permission to conduct the research was sought from all relevant gatekeepers. This study is set against the behaviourist, cognitive and constructivist learning frameworks. Findings from this study affirmed the numerous benefits of including e-assessments as part of the assessment method. However, further improvements to the design of the isiZulu quiz e-test were suggested.Keywords: e-assessment; second language isiZulu; student perceptions;Moodle; Learning Management Systems
Across continents: A comparison of African and Australian academics' online preparedness
The COVID-19 pandemic has disrupted higher education across the globe, in particular the shift from face-to-face teaching and assessment, as well as interaction with students. In 2020, an online survey was distributed to African and Australian higher education academics to gather insights into academicsâ transformation of educational practices during the early stages of the COVID-19 pandemic. In particular it focused on the effects on the quality of teaching, learning and assessment. The survey questions investigated the comparison of the use of teaching and assessment technologies prior to, and during the COVID-19 pandemic; academicsâ experiences with the sudden shift to work from home (WFH) arrangements and quality assurance measures for digital technologies. The sample included 71 academics across 12 Australian universities/tertiary institutions and 278 academics across 21 African higher education institutions. This study identified that while many Australian academics had prior experience and training in online/blended delivery, African academics, despite not having formal training in digital pedagogy, rated themselves as more than average in their ability to adopt technology for the online environment, just as the Australian cohort had. The most effective online tools adopted during the crisis in the African region were Zoom and WhatsApp while in the Australian region the learning management system (LMS) was the most popular. The major factors that affected African and Australian studentsâ ability to engage online included lack of access to connectivity and devices, technological competency and emotional and social factors. The results suggest that the predominant challenges faced by students as reported by academics across both continents in the âforcedâ remote work environment other than general anxiety about COVID-19 were social isolation (Aguilera-Hermida, 2020), connectivity for their students and the lack of a balanced work life (Kotteeswari & Sharief, 2014; Oliveira et al., 2021). This study has implications on institutionsâ readiness in terms of capacity building for academic staff, infrastructure and support during digital delivery of courses
Experiences of female academics in Australia during COVID-19: Opportunities and challenges
An online survey collected data on a range of female academic experiences globally gaining 260 responses with 144 Australian specific academicsâ responses (55% of total responses). The pandemic has highlighted positive opportunities such as online teaching and skill development, flexibility, time efficiency, increased collaboration, and time for research. In terms of challenges identified responses indicate an increased workload, less motivation for career progression, and perceptions of greater and obvious gender disparity and bias against female academics. Australia is often referred to as a âlucky countryâ which can further be enriched though fostering its rich and diverse female academic community into the future. Rapid measures to support women immediately and with longer-term solutions that address gender equity is critical for female academics to ensure future engagement of female academics for positive economic and social growth as a nation
Conceptualising digital capital in higher education institutions, its value during Covid 19 pandemic and beyond
No Abstract
Glycine-rich RNA binding protein of Oryza sativa inhibits growth of M15 E. coli cells
<p>Abstract</p> <p>Background</p> <p>Plant glycine-rich RNA binding proteins have been implicated to have roles in diverse abiotic stresses.</p> <p>Findings</p> <p><it>E. coli </it>M15 cells transformed with full-length rice glycine-rich RNA binding protein4 (OsGR-RBP4), truncated rice glycine-rich RNA binding protein4 (OsGR-RBP4ÎC) and rice FK506 binding protein (OsFKBP20) were analyzed for growth profiles using both broth and solid media. Expression of OsGR-RBP4 and OsGR-RBP4ÎC proteins caused specific, inhibitory effect on growth of recombinant M15 <it>E. coli </it>cells. The bacterial inhibition was shown to be time and incubation temperature dependent. Removal of the inducer, IPTG, resulted in re-growth of the cells, indicating that effect of the foreign proteins was of reversible nature. Although noted at different levels of dilution factors, addition of purified Os-GR-RBP4 and OsGR-RBP4ÎC showed a similar inhibitory effect as seen with expression inside the bacterial cells.</p> <p>Conclusions</p> <p>Expression of eukaryotic, stress-associated OsGR-RBP4 protein in prokaryotic <it>E. coli </it>M15 cells proves injurious to the growth of the bacterial cells. <it>E. coli </it>genome does not appear to encode for any protein that has significant homology to OsGR-RBP4 protein. Therefore, the mechanism of inhibition appears to be due to some illegitimate interactions of the OsGR-RBP4 with possibly the RNA species of the trans-host bacterial cells. The detailed mechanism underlying this inhibition remains to be worked out.</p
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in southern Africa has been characterised by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, whilst the second and third waves were driven by the Beta and Delta variants, respectively1-3. In November 2021, genomic surveillance teams in South Africa and Botswana detected a new SARS-CoV-2 variant associated with a rapid resurgence of infections in Gauteng Province, South Africa. Within three days of the first genome being uploaded, it was designated a variant of concern (Omicron) by the World Health Organization and, within three weeks, had been identified in 87 countries. The Omicron variant is exceptional for carrying over 30 mutations in the spike glycoprotein, predicted to influence antibody neutralization and spike function4. Here, we describe the genomic profile and early transmission dynamics of Omicron, highlighting the rapid spread in regions with high levels of population immunity
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and illuminate the distinct dispersal dynamics of variants of concern-particularly Alpha, Beta, Delta, and Omicron-on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve while the continent faces many emerging and reemerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.
The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood. In this study, we describe the genomic epidemiology using a dataset of 8746 genomes from 33 African countries and two overseas territories. We show that the epidemics in most countries were initiated by importations predominantly from Europe, which diminished after the early introduction of international travel restrictions. As the pandemic progressed, ongoing transmission in many countries and increasing mobility led to the emergence and spread within the continent of many variants of concern and interest, such as B.1.351, B.1.525, A.23.1, and C.1.1. Although distorted by low sampling numbers and blind spots, the findings highlight that Africa must not be left behind in the global pandemic response, otherwise it could become a source for new variants
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
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