THE PATTERN OF ORGANOPHOSPHORUS COMPOUNDS POISONING AT A TERTIARY CARE TEACHING HOSPITAL AND MEDICAL COLLEGE IN NORTHERN INDIA

Objective: A retrospective study was conducted in a tertiary care hospital collaborated with a medical college, to analyze the drug therapy including antidotes administered and pattern of Organophosphorous compounds poisoning.  Material and methods: The data are analytically drawn from record sheets of Organophosphorous poisoning patients. The collected tabulated data were statistically analyzed with SPSS version for the pattern of Organophosphorous compounds poisoning. Results: The demographic data of 122 Organophosphorous poisoning clinical cases documented 84.42 % suicidal tendency and 15.57 % accidental exposure of patients, 66.39 % in the age of 15-24 years, and 70.49 % were females and 70.49 % from a rural background, and 29.50 % from an urban background. Before pharmacotherapy, all patients were subjected to general supportive measures including stomach wash, and patients were administered pharmacotherapy consisting of Pralidoxime (23.77 %) and Atropine (41.80 %).  Conclusion: This present concluded that patients diagnosed with Organophosphorous poisoning can be managed by alone administration of atropine as an antidote which is available as a cost-effective drug as compared to Pralidoxime. Thus cost-effectiveness can be significantly reduced by the rational drug use and strict implementation of the pesticide act to further strengthen the proper maintenance of procurement of Organophosphorous compounds for exclusive agricultural purpose

Factors affecting maternal health care seeking behaviour in northeast states, India: evidence from district level household survey-4 (2012-2013)

Background: In context of reducing maternal mortality ratio, Government of India has implemented various programs and public health facility centres in order to provide quality services at the time of delivery. In this paper, we assessed the factors for home, private and public health facility sector utilization of delivery care in Northeast state, India. District Level Household Survey fourth round was used to carried out analysis and data was extracted for the childbirth during the last five years preceding the survey.Methods: The outcome variable was categorical, thus multinomial logistic regression was used to assess the factors of each variable independently on the predictor variables. To check the collinearity, variance inflation factor (VIF) was computed for all variables prior to inclusion of multilevel logistic regression.Results: This shows that equal proportion of delivery was conducted at home (45%) and public health facility (45.2%) in comparison with private health facility (9.8%). For the choice set of public versus home, women with higher number of living children, wealth quintile and living in urban areas were associated with greater odds of delivering at public health facility centres.Conclusions: The initiative programs can be implemented by the government by sending trained professionals with supplements required by pregnant women at each and every district in order to promote maternal health and recruit more interdisciplinary team, which will be responsible for maintaining women and infant health, and thus providing appropriate medical advice

Backpropagaton in Hl7 in Medical Informatics to Analysis Speed of Sending Data

In this paper, analysis the speed of sending message in Healthcare standard 7 with the use of back propagation in neural network. Various algorithms are define in backpropagtion in neural network we can use trainlm algorithm for sending message purpose. This algorithm appears to be fastest method for training moderate sized feedforward neural network. It has a very efficient matlab implementation. The need of trainlm algorithm are used for analysis, increase the speed of sending message faster and accurately and more efficiently. The proposed work is used in healthcare medical data. With the use of backpropagation in health care standard seven (HL7) sending message between two systems. To increase the speed of the healthcare sending data we can use Train LM algorithm. Train LM algorithm is more fastest algorithm it can be increase efficiency and improve accuracy of the system and also provide real time application. To increase speed of sending message these algorithm used. With the use of this algorithm it can be decreasing time of sending message to the other system

Database Extract Information Using Genetic Algorithm and Sending Message in HL7 Formatted Using Back Propagation

To analysis the speed of sending message in Healthcare standard 7 with the use of back propagation in neural network. Various algorithms are define in back propagation in neural network we can use back propagation algorithm for sending message purpose. Genetic Algorithm are used to extract information and send these information with this algorithm appears to be fastest method for training moderate sized feed forward neural network. It has a very efficient mat lab implementation. The need of this algorithm are used for analysis, increase the speed of sending message faster and accurately and more efficiently

Oral Rhabdomyosarcoma: a review

Rhabdomyosarcoma (RMS) is a rare malignant soft tissue neoplasm comprised of cells derived from the primitive mesen¬chyme. About 35% of RMS arises in the head and neck, are are classified as parameningeal and non-parameningeal forms. These are the most common soft tissue sarcoma of the children, adolescents and young adults. Their etiopathogenesis and its molecular relevance have been emphasized. The first line of treatment is radical excision and this is usually supplemented by radiotherapy. It is believed that adjunct combination chemotherapy may greatly improve the prognosis. Inadequately treated tumours grow in an infiltrative manner and recur in a high percentage of cases. Bone does not constitute an effective barrier to the growth of the tumour and bone invasion is a frequent finding in head and neck rhabdomyosarcomas

ACUTE SUICIDAL POISONING BY ALUMINUM PHOSPHIDE: RARE CASE REPORT FROM NORTHERN RURAL INDIA

Aluminum phosphide (ALP) is a highly toxic pesticide and is lethal if abused as a suicidal agent invariably. The ALP or a celphos powder is a major contributor to mortality, as such celphos poisoning lacks a specific antidote. The management of the patients includes fast decontamination and all international protocol supportive measures. The ALP poisoning has gained enormous interest with the spike in the number of cases due to its increased use for non-agricultural purposes as well. The easy ease of availability and laxity in the implementation of the sale of pesticides has eventually led to misuse, rather an abuse for the commitment of suicide. Celphos powder is commonly available in the form of tablets. This is a case of suicidal consumption of ALP by 54 years old male, a farmer by occupation. According to our interpretation, we believe that strict implementation of pesticide laws must be enforced and suicide help awareness programs under the banner of government and non-government organizations must come in the front line up

DIABETES MELLITUS: A REVIEW WITH EDGE OF SGLT2 INHIBITORS

The relative (Type 2 DM) or absolute (Type 1 DM) deficiency of insulin hormone could result into hyperglycemia, which is a characteristic feature of diabetes mellitus. Diabetes mellitus is a leading cause of morbidity and mortality because of its associated complications viz. Neuropathy, Nephropathy, Retinopathy, Cardiovascular disorders.The feature which has to be noted down is the death of individuals before the age of 70 y, which is attributable to high blood glucose levels. According to WHO diabetes mellitus will be the seventh leading cause of deaths till 2030.The induction of glycosuria as meant for gly­caemiac control in patients with DM is an extension of the physiological role of renal TmG to curb the menace of hyperglycemia. The first biologically derived SGLT2 inhibitor phlorizin, isolated in 1835 from the root bark of apple tree, was not developed as an antihyperglycaemic drug because of rapid degradation by lactase-phlorizin hydrolase and poor absorption from the gastrointestinal tract. Other glycoside moieties derived from phlorizin struc­ture have subsequently been developed recently