714 research outputs found
Hyperkahler Metrics from Periodic Monopoles
Relative moduli spaces of periodic monopoles provide novel examples of
Asymptotically Locally Flat hyperkahler manifolds. By considering the
interactions between well-separated periodic monopoles, we infer the asymptotic
behavior of their metrics. When the monopole moduli space is four-dimensional,
this construction yields interesting examples of metrics with self-dual
curvature (gravitational instantons). We discuss their topology and complex
geometry. An alternative construction of these gravitational instantons using
moduli spaces of Hitchin equations is also described.Comment: 23 pages, latex. v2: an erroneous formula is corrected, and its
derivation is given. v3 (published version): references adde
Optical band edge shift of anatase cobalt-doped titanium dioxide
We report on the optical properties of magnetic cobalt-doped anatase phase
titanium dioxide Ti_{1-x}Co_{x}O_{2-d} films for low doping concentrations, 0
<= x <= 0.02, in the spectral range 0.2 to 5 eV. For well oxygenated films (d
<< 1) the optical conductivity is characterized by an absence of optical
absorption below an onset of interband transitions at 3.6 eV and a blue shift
of the optical band edge with increasing Co concentration. The absence of below
band gap absorption is inconsistent with theoretical models which contain
midgap magnetic impurity bands and suggests that strong on-site Coulomb
interactions shift the O-band to Co-level optical transitions to energies above
the gap.Comment: 5 pages, 4 figures, 1 table; Version 2 - major content revisio
TRial to Assess Implementation of New research in a primary care Setting (TRAINS): study protocol for a pragmatic cluster randomised controlled trial of an educational intervention to promote asthma prescription uptake in general practitioner practices
Background
There is a marked increase in unscheduled care visits in school-aged children with asthma after returning to school in September. This is potentially associated with children not taking their asthma preventer medication during the school summer holidays. A cluster randomised controlled trial (PLEASANT) was undertaken with 1279 school-age children in 141 general practices (71 on intervention and 70 on control) in England and Wales. It found that a simple letter sent from the family doctor during the school holidays to a parent with a child with asthma, informing them of the importance of taking asthma preventer medication during the summer relatively increased prescriptions by 30% in August and reduced medical contacts in the period September to December. Also, it is estimated there was a cost-saving of ÂŁ36.07 per patient over the year. We aim to conduct a randomised trial to assess if informing GP practices of an evidence-based intervention improves the implementation of that intervention.
Methods/design
The TRAINS studyâTRial to Assess Implementation of New research in a primary care Settingâis a pragmatic cluster randomised implementation trial using routine data. A total of 1389 general practitioner (GP) practices in England will be included into the trial; 694 GP practices will be randomised to the intervention group and 695 control group of usual care. The Clinical Practice Research Datalink (CPRD) will send the intervention and obtain all data for the study, including prescription and primary care contacts data. The intervention will be sent in June 2021 by postal and email to the asthma lead and/or practice manager. The intervention is a letter to GPs informing them of the PLEASANT study findings with recommendations. It will come with an information leaflet about PLEASANT and a suggested reminder letter and SMS text template.
Discussion
The trial will assess if informing GP practices of the PLEASANT trial results will increase prescription uptake before the start of the school year. The hope is that the intervention will increase the implementation of PLEASANT work and then increase prescription uptake during the summer holiday prior to the start of school
Non-linear instability of Kerr-type Cauchy horizons
Using the general solution to the Einstein equations on intersecting null
surfaces developed by Hayward, we investigate the non-linear instability of the
Cauchy horizon inside a realistic black hole. Making a minimal assumption about
the free gravitational data allows us to solve the field equations along a null
surface crossing the Cauchy Horizon. As in the spherical case, the results
indicate that a diverging influx of gravitational energy, in concert with an
outflux across the CH, is responsible for the singularity. The spacetime is
asymptotically Petrov type N, the same algebraic type as a gravitational shock
wave. Implications for the continuation of spacetime through the singularity
are briefly discussed.Comment: 11 pages RevTeX, two postscript figures included using epsf.st
Open-label, cluster randomised controlled trial and economic evaluation of a brief letter from a GP on unscheduled medical contacts associated with the start of the school year: the PLEASANT trial
BACKGROUND: Asthma is seasonal with peaks in exacerbation rates in school-age children associated with the return to school following the summer vacation. A drop in prescription collection in August is associated with an increase in the number of unscheduled contacts after the school return. OBJECTIVE: To assess whether a public health intervention delivered in general practice reduced unscheduled medical contacts in children with asthma. DESIGN: Cluster randomised trial with trial-based economic evaluation. Randomisation was at general practice level, stratified by size of practice. The intervention group received a letter from their general practitioner (GP) in late July outlining the importance of (re)taking asthma medication before the return to school. The control group was usual care. SETTING: General practices in England and Wales. PARTICIPANTS: 12â179 school-age children in 142 general practices (70 randomised to intervention). MAIN OUTCOME: Proportion of children aged 5-16 years who had an unscheduled contact in September. Secondary endpoints included collection of prescriptions in August and medical contacts over 12 months (September-August). Economic endpoints were quality-adjusted life-years gained and health service costs. RESULTS: There was no evidence of effect (OR 1.09; 95%âCI 0.96 to 1.25 against treatment) on unscheduled contacts in September. The intervention increased the proportion of children collecting a prescription in August by 4% (OR 1.43; 95%âCI 1.24 to 1.64). The intervention also reduced the total number of medical contacts between September-August by 5% (incidence ratio 0.95; 95%âCI 0.91 to 0.99).The mean reduction in medical contacts informed the health economics analyses. The intervention was estimated to save ÂŁ36.07 per patient, with a high probability (96.3%) of being cost-saving. CONCLUSIONS: The intervention succeeded in increasing children collecting prescriptions. It did not reduce unscheduled care in September (the primary outcome), but in the year following the intervention, it reduced the total number of medical contacts. TRIAL REGISTRATION NUMBER: ISRCTN03000938; Results
Examination of silver-graphite lithographically printed resistive strain sensors
This paper reports the design and manufacture of three differing types of resistive strain sensitive structures fabricated using the Conductive Lithographic Film (CLF) printing process. The structures, utilising two inks prepared with silver and graphite particulates as the conductive phase, have been analysed to determine electrical and mechanical properties with respect to strain, temperature and humidity when deposited on four alternative substrate materials (GlossArt, PolyArt, Teslin and Melinex)
Conductive lithographic film fabricated resistive strain gauges
This paper reports progress in sensor fabrication by the
Conductive Lithographic Film (CLF) printing process.
Work describing strain sensitive structures manufactured
using a modified printing process and conductive inks are
addressed The performance of a âsingle inkâ strain
sensitive structure when printed on six altemative polymer
substrates (GlossArt, PolyArt, Teslin. Mylar C, Mylar and
Kapton) is analysed Though not intending to compete with
conventional gauges in high tolerance measurement, the
structures exhibit properties that indicate suitability for
novel applications
Characterisation of lithographically printed resistive strain gauges
This paper reports progress in sensor fabrication by
the conductive lithographic film (CLF) printing process.Work describing
strain-sensitive structures manufactured using a modified
printing process and conductive inks is addressed. The performance
of a âsingle-inkâ strain-sensitive structure when printed
on six alternative substrates (GlossArt, PolyArt, Teslin, Mylar C,
Melinex, and Kapton) is analyzed. Though not intending to compete
with conventional gauges in high-tolerance measurement, the
structures exhibit properties that indicate suitability for novel applications
Yellow fever in the Gambia, 1978-1979 : epidemiologic aspects with observations on the occurrence of orungo virus infections
Dynamics of Simple Balancing Models with State Dependent Switching Control
Time-delayed control in a balancing problem may be a nonsmooth function for a
variety of reasons. In this paper we study a simple model of the control of an
inverted pendulum by either a connected movable cart or an applied torque for
which the control is turned off when the pendulum is located within certain
regions of phase space. Without applying a small angle approximation for
deviations about the vertical position, we see structurally stable periodic
orbits which may be attracting or repelling. Due to the nonsmooth nature of the
control, these periodic orbits are born in various discontinuity-induced
bifurcations. Also we show that a coincidence of switching events can produce
complicated periodic and aperiodic solutions.Comment: 36 pages, 12 figure
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