Validity and Reliability of the Indonesian Version of SF-36 Quality of Life Questionnaire on Patients with Permanent Pacemakers

Aim: to construct and validate Indonesian version of SF-36. Methods: this is a cross-sectional study, which consist of 2 stages process: 1) language and cultural adaption; and 2) validity and reliability evaluation. We evaluated 32 pacemaker patients during language and cultural adaptation stage and 20 pacemaker patients during validity and reliability evaluation stages from September 2014 to August 2015. We followed cross-cultural adaptation guideline to produce Indonesian version of the questionnaire. The final translated questionnaire was checked by assessing the correlation of SF-36 and 6-minutes walking test (6MWT) and NT pro-BNP result. Results: Indonesian version of SF-36 showed positive correlation between 6MWT result and physical functioning (PF) (r=0.363; p=0.001) and negative correlation between NT pro-BNP score with general health (GH) (r=-0.269; p=0.020) and mental health (MH) (r=-0.271; p=0.019). The internal consistency of Indonesian version of SF-36 questionnaire, which measured by Cronbach’s alpha, was good with value of >0.70. Repeatability between day 1 and day 8 was good, with strong positive correlation (r=0.626; p=0.003). Conclusion: the Indonesian version of SF-36 could be used as a general questionnaire to assess quality of life in patients with permanent pacemaker

Non-Hermitian control of optical turbulence in systems with fractional dispersion

We show an efficient mechanism to control optical turbulence in systems with different dispersion laws, including parabolic, sub-diffractive, hyper-diffractive or general fractional dispersion. The method is based on the modification of the energy cascade through spatial scales leading to turbulence: a non-Hermitian spatio-temporal periodic potential allows unidirectional coupling between modes in the excitation process. We prove a significant increase and reduction of the energy flow in turbulent states, by either condensing the excitation towards small wave-numbers or affecting the energy transfer towards large wave-number. The study is based on the complex Fractional Ginzburg–Landau equation, a universal model for pattern formation and turbulence in a wide range of systems. The enhancement or reduction of turbulence is indeed dependent on the imposed direction of the energy flow, controlled by the phase shift between the real and imaginary parts of the temporal oscillation of the non-Hermitian potential.Peer ReviewedPostprint (published version

Optical turbulence control by non-Hermitian potentials

We propose a method for a control of turbulence by modifying the excitation cascade leading to turbulence. The method is based on the asymmetric coupling between the spatiotemporal excitation modes by non-Hermitian potentials. The non-Hermitian potentials are recently known to enable unidirectional coupling between modes. We demonstrate that such unidirectional coupling towards larger (smaller) wave numbers can increase (reduce) the energy flow in turbulent states, and therefore, influence the character of turbulence. The study is based on the complex Ginzburg-Landau equation, a universal model for pattern formation and turbulence in a wide range of systems including nonlinear optical resonators. We show that enhancement or reduction of turbulence is indeed dependent on the imposed direction of the energy flow, controlled by the phase shift between the real and imaginary parts of the temporal oscillation of the non-Hermitian potential.Peer ReviewedPostprint (published version

Turbulence control by non-Hermitian potentials

We propose a method to control turbulence by the introduction a non-Hermitian spatiotemporal modulation, based on the energy redirection from unstable to stable modes by the unidirectional coupling induced by these potentials and so, influence and slow down the excitation cascade of turbulenceObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraPostprint (author's final draft

Perancangan Cerita Bergambar Dengan Teknik Ilustrasi Realis Mengenai Sejarah Rumah “Kampoeng Keamasan”

Perancangan ini merupakan perancangan buku cerita bergambar yang membahas tentang sejarah dari rumah – rumah tua di “Kampoeng Kemasan” untuk dewasa muda. Latar belakang perancangan didasarkan pada realita yang ada bahwa masih kurangnya pengetahuan atau kesadaran akan cerita sejarah dan peninggalan di “Kampoeng Kemasan”. Oleh sebab itu sangat penting untuk dilakukan perancangan ini agar masyarakat dalam maupun luar Gresik terutama dewasa muda dapat mengetahui bagaimana sejarah dari “Kampoeng Kemasan”, sehingga pada akhirnya dapat mendukung pengembangan “Kampoeng Kemasan” untuk kedepannya

Light control by Non-Hermitian modulation in multimode fiber

We show that a non-Hermitian modulation of the potential along the nonlinear multimode fibers controls dynamics of propagating radiation. Specifically we consider simultaneous modulation of the refraction index and gain/loss profile. We observe that the non-Hermitian modulation introduces a unidirectional and controllable coupling towards the lower/higher order transverse modes, depending on the potential parameters. Such effect may enhance the beam self-cleaning phenomena. On the contrary, coupling towards higher order modes may enhance pulsing, turbulence and, eventually help in super-continuum generation.Peer ReviewedObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraPostprint (published version

Non-Hermitian mode cleaning in periodically modulated multimode fibers

We show that the simultaneous modulation of the propagation constant and of the gain/loss coefficient along the multimode fibers results in unidirectional coupling among the modes, which, depending on the modulation parameters, leads to the enhancement or reduction of the excitation of higher order transverse modes. In the latter case, effective mode-cleaning is predicted, in ideal case resulting in single-mode spatially coherent output. The effect is semi-analytically predicted on a simplified Gaussian beam approximation and numerically proven by solving the wave propagation equation introducing the modulated potential.Peer ReviewedObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i InfraestructuraPreprin

Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment

BACKGROUND AIMS Cultured patient-specific keratinocyte sheets have been used clinically since the 1970s for the treatment of large severe burns. However, despite significant developments in recent years, successful and sustainable treatment is still a challenge. Reliable, high-quality grafts with faster availability and a flexible time window for transplantation are required to improve clinical outcomes. METHODS Keratinocytes are usually grown in vitro at 37°C. Given the large temperature differences in native skin tissue, the aim of the authors' study was to investigate thermal conditioning of keratinocyte sheet production. Therefore, the influence of 31°C, 33°C and 37°C on cell expansion and differentiation in terms of proliferation and sheet formation efficacy was investigated. In addition, the thermal effect on the biological status and thus the quality of the graft was assessed on the basis of the release of wound healing-related biofactors in various stages of graft development. RESULTS The authors demonstrated that temperature is a decisive factor in the production of human keratinocyte sheets. By using specific temperature ranges, the authors have succeeded in optimizing the individual manufacturing steps. During the cell expansion phase, cultivation at 37°C was most effective. After 6 days of culture at 37°C, three times and six times higher numbers of viable cells were obtained compared with 33°C and 31°C. During the cell differentiation and sheet formation phase, however, the cells benefited from a mildly hypothermic temperature of 33°C. Keratinocytes showed increased differentiation potential and formed better epidermal structures, which led to faster biomechanical sheet stability at day 18. In addition, a cultivation temperature of 33°C resulted in a longer lasting and higher secretion of the investigated immunomodulatory, anti-inflammatory, angiogenic and pro-inflammatory biofactors. CONCLUSIONS These results show that by using specific temperature ranges, it is possible to accelerate the large-scale production of cultivated keratinocyte sheets while at the same time improving quality. Cultivated keratinocyte sheets are available as early as 18 days post-biopsy and at any time for 7 days thereafter, which increases the flexibility of the process for surgeons and patients alike. These findings will help to provide better clinical outcomes, with an increased take rate in severe burn patients

ANALISIS RELEVANSI NILAI INFORMASI AKUNTANSI DAN ASIMETRI INFORMASI SEBELUM DAN SESUDAH KONVERGENSI IFRS PADA PERUSAHAAN LQ-45

The Financial Accounting Standards in Indonesia has referred to IFRS. The principles of IFRS which are fair value and full dis-closure are expected to generate a certain quality of accounting information. Fair value is market-based measured while full dis-closure is explaning about disclosing all the information which are important in decision making. One of the issue caused by in-formation asymmetry is agency conflict where agent acts for his own behalf because he knows much more information rather than principal about company condition, so as the information is not relevant to be used as the source of decision making. There-fore, the aim of this study is to analyse whether the convergence of IFRS can increase the value relevance of accounting infor-mation and decrease the information asymmetry. The research design is descriptive. The object of the research are the compa-nies which are listed as LQ-45 in 2010-2014 (2012 as cutoff) with 45 companies selected by purposive sampling technique. Technique of data analysis which are used are multiple linier regression and paired t test samples. The results showed that there are increasing of value relevance of accounting information and signicicantly decreasing of the information asymmetry after IFRS convergence in Indonesia

Combined effect of atmospheric nitrogen deposition and climate change on temperate forest soil biogeochemistry: A modeling approach

International audienceAtmospheric N deposition is known to severely impact forest ecosystem functioning by influencing soil biogeochemistry and nutrient balance, and consequently tree growth and overall forest health and biodiversity. Moreover, because climate greatly influences soil processes, climate change and atmospheric N deposition must both be taken into account when analysing the evolution of forest ecosystem status over time. Dynamic biogeochemical models have been developed to test different climate and atmospheric N deposition scenarios and their potential interactions in the long term. In this study, the ForSAFE model was used to predict the combined effect of atmospheric N deposition and climate change on two temperate forest ecosystems in France dominated by oak and spruce, and more precisely on forest soil biogeochemistry, from today to 2100. After a calibration step and following a careful statistical validation process, two atmospheric N deposition scenarios were tested: the current legislation in Europe (CLE) and the maximum feasible reduction (MFR) scenarios. They were combined with three climate scenarios: current climate scenario, worst-case climate scenario (A2) and best-case climate scenario (B1). The changes in base saturation and inorganic N concentration in the soil solution were compared across all scenario combinations, with the aim of forecasting the state of acidification, eutrophication and forest ecosystem recovery up to the year 2100. Simulations highlighted that climate had a stronger impact on soil base saturation, whereas atmospheric deposition had a comparative effect or a higher effect than climate on N concentration in the soil solution. Although deposition remains the main factor determining the evolution of N concentration in soil solution, increased temperature had a significant effect. Results also highlighted the necessity of considering the joint effect of both climate and atmospheric N deposition on soil biogeochemistry