Academic Resilience of Athletic Training Students During COVID-19 Pandemic

OBJECTIVE (1) To describe resilience in athletic training students enrolled in professional coursework during the spring 2020 semester, and (2) to determine the association between resilience and academic performance during the spring 2020 semester. MAIN OUTCOME MEASURESDescriptive statistics for GPA were calculated for Fall 2019, Spring 2020, cumulative Fall 2019, cumulative Spring 2020 (ie., current), change in cumulative GPA, and ARS-30 total score. The primary analysis was a Pearson correlation between change in cumulative GPA and ARS-30 total score. A secondary analysis was conducted to evaluate change in cumulative Fall 2019 and Spring 2020 GPA with a paired t-test. Cohen’s d effect size was calculated for the paired t-test. Alpha level was set at 0.05

Looking for a Black Cat in a Dark Room: Security Visualization for Cyber-Physical System Design and Analysis

Today, there is a plethora of software security tools employing visualizations that enable the creation of useful and effective interactive security analyst dashboards. Such dashboards can assist the analyst to understand the data at hand and, consequently, to conceive more targeted preemption and mitigation security strategies. Despite the recent advances, model-based security analysis is lacking tools that employ effective dashboards---to manage potential attack vectors, system components, and requirements. This problem is further exacerbated because model-based security analysis produces significantly larger result spaces than security analysis applied to realized systems---where platform specific information, software versions, and system element dependencies are known. Therefore, there is a need to manage the analysis complexity in model-based security through better visualization techniques. Towards that goal, we propose an interactive security analysis dashboard that provides different views largely centered around the system, its requirements, and its associated attack vector space. This tool makes it possible to start analysis earlier in the system lifecycle. We apply this tool in a significant area of engineering design---the design of cyber-physical systems---where security violations can lead to safety hazards

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

Environmental factors, including pesticides, have been linked to autism and neurodegeneration risk using retrospective epidemiological studies. Here we sought to prospectively identify chemicals that share transcriptomic signatures with neurological disorders, by exposing mouse cortical neuron-enriched cultures to hundreds of chemicals commonly found in the environment and on food. We find that rotenone, a pesticide associated with Parkinson's disease risk, and certain fungicides, including pyraclostrobin, trifloxystrobin, famoxadone and fenamidone, produce transcriptional changes in vitro that are similar to those seen in brain samples from humans with autism, advanced age and neurodegeneration (Alzheimer's disease and Huntington's disease). These chemicals stimulate free radical production and disrupt microtubules in neurons, effects that can be reduced by pretreating with a microtubule stabilizer, an antioxidant, or with sulforaphane. Our study provides an approach to prospectively identify environmental chemicals that transcriptionally mimic autism and other brain disorders

What asteroseismology can do for exoplanets

We describe three useful applications of asteroseismology in the context of exoplanet science: (1) the detailed characterisation of exoplanet host stars; (2) the measurement of stellar inclinations; and (3) the determination of orbital eccentricity from transit duration making use of asteroseismic stellar densities. We do so using the example system Kepler-410 (Van Eylen et al. 2014). This is one of the brightest (V = 9.4) Kepler exoplanet host stars, containing a small (2.8 Rearth) transiting planet in a long orbit (17.8 days), and one or more additional non-transiting planets as indicated by transit timing variations. The validation of Kepler-410 (KOI-42) was complicated due to the presence of a companion star, and the planetary nature of the system was confirmed after analyzing a Spitzer transit observation as well as ground-based follow-up observations.Comment: 4 pages, Proceedings of the CoRoT Symposium 3 / Kepler KASC-7 joint meeting, Toulouse, 7-11 July 2014. To be published by EPJ Web of Conference

Thromboembolism After Intramedullary Nailing for Metastatic Bone Lesions.

BACKGROUND: The risk of venous thromboembolism (VTE) in patients undergoing intramedullary nailing for skeletal metastatic disease is currently undefined. The purpose of our study was to determine the risk of thromboembolic events, to define the risk factors for VTE, and to define the rate of wound complications in this population. METHODS: A retrospective review of surgical databases at three National Cancer Institute (NCI)-designated cancer centers identified 287 patients with a total of 336 impending or pathologic long-bone fractures that were stabilized with intramedullary nailing between February 2001 and April 2013. Statistical analysis was performed utilizing multivariable logistic regression and Fisher exact tests. RESULTS: The overall rate of VTE was twenty-four (7.1%) of the 336; thirteen (3.9%) were pulmonary embolism (PE), and eleven (3.3%), deep venous thrombosis (DVT). In two patients, adequate anticoagulation data were not available. We found no significant relationship between the type of anticoagulant used and VTE. There was a significant positive correlation found between lung-cancer histology and the development of VTE (p \u3c 0.001) or PE (p \u3c 0.001). The absence of radiation therapy approached significance (p = 0.06) with respect to decreased overall VTE risk. Wound complications were documented for 11 (3.3%) of the operations. CONCLUSIONS: There is a high rate of VTE among those with skeletal metastatic disease who undergo intramedullary nailing, even while receiving postoperative thromboembolic prophylaxis. Current anticoagulation protocols may be inadequate. Wound-complication risk with anticoagulant use in this population is low and should not be a deterrent to adequate anticoagulant use for this population

Performance evaluation of the board of directors in listed companies : a small state perspective

Purpose: The objectives of this paper are to analyse both individual and overall performance evaluations of the Board of Directors as carried out by Maltese Listed Companies (MLCs) and to assess the importance of such board evaluations to small shareholders. Design/Approach/Methodology: The study was designed around semi-structured interviews with fifteen MLC representatives and seven stockbrokers, as well as questionnaires administered to twenty-nine small shareholders. Findings: The findings indicate that, while Boards of Director evaluations are carried out in MLCs, they lack the necessary formal structures that specify critical evaluation measures. Thus one may infer that those charged with the responsibility of conducting evaluations are not being well determined. By departing from the recommendations of the Maltese Corporate Governance Code on performance evaluations, MLCs have generally opted to resort to an inward and more restricted style of evaluation, doing away with external or independent parties in the process. Practical Implications: Recommendations include the promotion of shareholder interest by enhancing their awareness of the benefits they will stand to gain from the process and by involving them more in the process. Originality/Value: The paper considers possible evaluation measures that may be aimed to enhance both shareholder and public confidence in the exercise and also other ways by which it may be improved. It thus contributes to the literature, as yet scarce, which relates to corporate governance in small states.peer-reviewe

Malaria Vaccines: Recent Advances and New Horizons.

The development of highly effective and durable vaccines against the human malaria parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor have taught that achieving this goal will be challenging; however, recent innovation in malaria vaccine research and a diverse pipeline of novel vaccine candidates for clinical assessment provides optimism. With first-generation pre-erythrocytic vaccines aiming for licensure in the coming years, it is important to reflect on how next-generation approaches can improve on their success. Here we review the latest vaccine approaches that seek to prevent malaria infection, disease, and transmission and highlight some of the major underlying immunological and molecular mechanisms of protection. The synthesis of rational antigen selection, immunogen design, and immunization strategies to induce quantitatively and qualitatively improved immune effector mechanisms offers promise for achieving sustained high-level protection

A Search for Light Hydrides in the Envelopes of Evolved Stars

We report a search for the diatomic hydrides SiH, PH, and FeH along the line of sight toward the chemically rich circumstellar envelopes of IRC+10216 and VY Canis Majoris. These molecules are thought to form in high temperature regions near the photospheres of these stars, and may then further react via gas-phase and dust-grain interactions leading to more complex species, but have yet to be constrained by observation. We used the GREAT spectrometer on SOFIA to search for rotational emission lines of these molecules in four spectral windows ranging from 600 GHz to 1500 GHz. Though none of the targeted species were detected in our search, we report their upper limit abundances in each source and discuss how they influence the current understanding of hydride chemistry in dense circumstellar media. We attribute the non-detections of these hydrides to their compact source sizes, high barriers of formation, and proclivity to react with other molecules in the winds.Comment: Accepted for publication in ApJ. 14 pages, 4 figures, 3 table