United Airlines wind shear incident of May 31, 1984

An incident involving wind shear on 31 May 1984 is discussed by an airline employee. The specs of the plane are given, the weather conditions are listed, and the actions taken by the flight crew are discussed

Planning fuel-conservative descents in an airline environmental using a small programmable calculator: Algorithm development and flight test results

A simple, airborne, flight-management descent algorithm was developed and programmed into a small programmable calculator. The algorithm may be operated in either a time mode or speed mode. The time mode was designed to aid the pilot in planning and executing a fuel-conservative descent to arrive at a metering fix at a time designated by the air traffic control system. The speed model was designed for planning fuel-conservative descents when time is not a consideration. The descent path for both modes was calculated for a constant with considerations given for the descent Mach/airspeed schedule, gross weight, wind, wind gradient, and nonstandard temperature effects. Flight tests, using the algorithm on the programmable calculator, showed that the open-loop guidance could be useful to airline flight crews for planning and executing fuel-conservative descents

On tiered small jump operators

Predicative analysis of recursion schema is a method to characterize complexity classes like the class FPTIME of polynomial time computable functions. This analysis comes from the works of Bellantoni and Cook, and Leivant by data tiering. Here, we refine predicative analysis by using a ramified Ackermann's construction of a non-primitive recursive function. We obtain a hierarchy of functions which characterizes exactly functions, which are computed in O(n^k) time over register machine model of computation. For this, we introduce a strict ramification principle. Then, we show how to diagonalize in order to obtain an exponential function and to jump outside deterministic polynomial time. Lastly, we suggest a dependent typed lambda-calculus to represent this construction

Pilates For Ballet

Pilates For Ballet is a certification thesis. I started with an interest in the connection between Pilates exercises and ballet technique. I set out to investigate the difference in my ballet training while I explored deeper into the Pilates curriculum. I was interested in its influence on the proper ballet technical alignment and the activation of the correct muscle groups to achieve it. I chose the BASI Pilates Certification Program to pursue my investigation. During each of the 12 seven hour lessons I not only learned how to execute and teach the exercises, but I received a great amount of information concerning anatomy and kinesiology as well. I had previously taken an anatomy and kinesiology for dancers course at LMU, so I came to BAS! knowing most of the information. Even so, BASI explained it in a different way, which reinforced it in my mind, and with relevance to Pilates vs. dance. I was able to compare the two aspects, which strengthened my understanding of the correct ways to use the body in each activity. My thesis describes how Pilates informs the student other anatomy and gives them the awareness to control it pertaining to specific goals. Finally, the student can apply this awareness and control to their body in a ballet classroom to maximize their technique and training

Doctor of Philosophy

dissertationAdvances in sequencing technologies have made it possible to generate large amounts of microbiological sequence data without culture methods. The data generated pose a significant data analysis challenge. This is especially true in clinical diagnostics where accurate and timely diagnoses are key. To enable infectious disease diagnostics, we created Taxonomer, a kmer-based metagenomics software tool, which can rapidly process large amounts of sequence data with accuracy and precision similar to slower alignment-based approaches. A kmer is a nucleotide subsequence of k length. Kmer exact matching is performed in RAM, utilizing data structures with rapid query times, making kmer approaches magnitudes faster than alignment methods. Prior to Taxonomer, other kmer-based methods were subject to high false positive rates. Taxonomer differs by 1) providing a workflow that reduces false-positives, 2) including host-transcript profiling, and 3) providing a novel protein kmer tool to identify viruses, which are typically too divergent to reliably identify using nucleotide sequence. A web-based front-end was created with the D3 enabled iobio framework. Reference sets utilized in Taxonomer were obtained from NCBI, GreenGenes, unite, and uniprot databases. A wide-range of simulated datasets and real clinical specimens were created or obtained to evaluate Taxonomer. Taxonomer was compared to previously published pipelines (SURPI), classifiers (Kraken, RDP classifier), and sequence alignment methods (BLAST, SNAP, RapSearch2, DIAMOND). Taxonomer was also iv compared to a commercially available respiratory virus panel and utilized on a large cohort of pneumonia positive patients that had previously undergone extensive microbiological diagnostics. Taxonomer had agreement at 98.7% with SURPI to assign reads at the phylum level. Taxonomer, RDP classifier, and Kraken classified simulated 16S rRNA reads correctly at the species level at 59.5, 61.7, and 46.0%, respectively. Protein classification using reads derived from viruses showed similar sensitivity to alignment-based methods with RapSearch2, and DIAMOND but with slightly decreased analysis times. Taxonomer provides an accurate workflow for processing samples in a diagnostic setting. It identifies bacteria, fungi, virus, and human transcripts from clinical specimens with accuracy comparable to alignment methods. Its web-based front-end makes it accessible to laboratories without significant compute resources

Pilates for Ballet

Pilates For Ballet is a certification thesis. I started with an interest in the connection between Pilates exercises and ballet technique. I set out to investigate the difference in my ballet training while I explored deeper into the Pilates curriculum. I was interested in its influence on the proper ballet technical alignment and the activation of the correct muscle groups to achieve it. I chose the BASI Pilates Certification Program to pursue my investigation. During each of the 12 seven hour lessons I not only learned how to execute and teach the exercises, but I received a great amount of information concerning anatomy and kinesiology as well. I had previously taken an anatomy and kinesiology for dancers course at LMU, so I came to BAS! knowing most of the information. Even so, BASI explained it in a different way, which reinforced it in my mind, and with relevance to Pilates vs. dance. I was able to compare the two aspects, which strengthened my understanding of the correct ways to use the body in each activity. My thesis describes how Pilates informs the student other anatomy and gives them the awareness to control it pertaining to specific goals. Finally, the student can apply this awareness and control to their body in a ballet classroom to maximize their technique and training

Response to: The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury

A response to and comment on The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury, by Haleema Shakur, Ian Roberts, et al