Sezonska dinamika primarne i sekundarne produkcije u šaranskim ribnjacima

Sezonska dinamika biomase i kvalitativnog sastava fitoplanktona, zooplanktona i makrozoobentosa je istraživana u odnosu na fizičke i hemijske faktore vodene sredine, međusobno kao i u odnosu na gajene ribe u tri zemljana bazena. Fitoplankton je imao veliki diverzitet vrsta, naročito jestivih, tokom prvog dela sezone. Kasnije, sa porastom temperature, ihtiomase, količine ekskreta riba, degradacijom nepojedene hrane kao i povremenim smanjenjem količine vode u jezerima, došlo je do promene u pravcu dominacije filamentoznih Cyanophyta. Zooplankton i makrozoobentos su tokom celog perioda istraživanja imali mali diverzitet vrsta. Sezonalna dinamika zooplanktona se karakterisala dominacijom dve Rotatoria, Brachionus angularis i Keratella tropica i malom Cladocera Bosmina longirostris u sva tri bazena. Makrozoobentos je imao malu gustinu i biomasu, a larvame Chironomidae su dominirale tokom cele sezone

USE OF BISPECTRAL INDEX (BIS) FOR MONITORING OF SEDATION AND TOTAL INTRAVENOUS ANESTHESIA (TIVA) IN PEDIATRIC PATIENTS UNDERGOING COLONOSCOPY

The objectives of this study were to determine whether there was a correlation between bispectral index (BIS) and Ramsey Sedation Scale (RSS) in regard to the type of sedation and total intravenous anesthesia (TIVA) during colonoscopy procedures in children, and to assess the utility of ketamine and propofol combination (ketofol) for this kind of procedures at children’s age. In our prospective study, 40 ASA I-II patients, 3 to 17 years of age, were randomly divided into two groups of 20 patients each.   After premedication with atropine and midazolam, sedation was induced with propofol and fentanyl in Group PF, whereas in Group PK propofol and ketamine were used for induction. Both groups were further divided into two subgroups depending on whether anesthesia was maintained with intermittent doses or continuous infusion of propofol. Ketamine and/or fentanyl were administered as bolus doses. Heart rate (HR), peripheral oxygen saturation (SpO2), RSS and BIS values of all patients were recorded every 5 minutes throughout the colonoscopy procedures.  The strongest degree of correlation between RSS and BIS existed when sedation or TIVA was maintained by the boluses of propofol and fentanyl. The use of ketamine significantly reduced the doses of propofol and fentanyl. BIS can be monitored in all pediatric patients in whom sedation and TIVA are administered during colonoscopy, but the effect of different anesthetics on the EEG signal should be considered in order to adequately assess the depth of sedation and anesthesia.Key words: awareness, monitoring, child, anesthetics, endoscop

Demographic and socioeconomic factors associated with cervical cancer screening among women in Serbia

ObjectivesEffective reduction of cervical cancer incidence and mortality requires strategic measures encompassing the implementation of a cost-effective screening technology. Serbia has made significant strides, introducing organized cervical cancer screening in 2012. However, various impediments to screening implementation persist. The aim of the study was to estimate the socioeconomic factors associated with cervical cancer screening among women in Serbia.MethodsData from 2019 National Health Survey of the population of Serbia were used in this study. The study is cross sectional survey on a representative sample of the population of Serbia. Present total number of participants analyzed in survey 6,747.ResultsIn Serbia, 67.2% of women have done a Pap test at any time during their lives, of which 46.1% of women have undergone cervical cancer screening in the past 3 years. About a quarter of women have never undergone a Pap test in their life (24.3%). The probability of never having a Pap test have: the youngest age group (15–24 years) is 1.3 times more likely than the oldest age group (OR = 1.31), unmarried women 0.3 times more often than married women (OR = 0.37), respondents with basic education 0.9 times more often than married women (OR = 0.98), the women of lower socioeconomic status 0.5 times more often than respondents of high socioeconomic status (OR = 0.56).ConclusionEnhancement of the existing CCS would be the appropriate public health approach to decrease the incidence and mortality of cervical cancer in the Republic of Serbia

Procena trofičkog statusa akumulacije očaga (Lazarevac, Srbija) posredstvom Carlsonovog indeksa

Trofički status se može definisati kao ukupna težina živog biološkog materijala (biomase) u nekom vodenom telu na određenom lokalitetu i u određeno vreme. Trofički status nekog vodenog tela može se proceniti na osnovu merenja specifičnih parametara i predstavlja biološki odgovor na spoljašnje faktore, kao što su količina nutrijenata, sezonske promene, ispaša, mešanje vode itd. Procena trofičkog statusa jezera ili akumulacije je od velikog značaja. Postoje različiti kriterijumi za procenu trofičkog stanja jezera, kao što su: koncentracija nutrijenata, produktivnost, kvantitativni i kvalitativni sastav flore i faune, dostupnost kiseonika i morfometrija jezera. Međutim, imajući u vidu da je multiparametarski indeks nepraktičan, Carlson je predložio indekse trofičkog stanja (TSIs) koji su znatno jednostavniji za upotrebu od multiparametarskog indeksa. Ovi indeksi kao bazu za klasifikaciju trofičkih stanja koriste algalnu biomasu. U tom smislu koriste se tri parametra za izračunavanje ovih indeksa: koncentracija hlorofila a, ukupni fosfor i providnost izmerena Secchi diskom. Svaka od ove tri promenljive se može koristiti za klasifikaciju statusa vodenog tela, ali je hlorofila a najznačajniji parametar s obzirom da je direktni pokazatelj algalne biomase. Opseg Carlson-ovog trofičnog indeksa obuhvata vrednosti od 0 do 100. Vrednosti ispod 40 odgovaraju oligotrofnim, od 40 do 50 mezotrofnim, od 50 do 70 eutrofnim, a preko 70 hipereutrofnim jezerima i akumulacijama. Glavna prednost ovog indeksa je što odnos između tri parametra može ukazati na određene uslove koji vladaju u datom jezeru ili akumulaciji, a tiču se faktora koji limitiraju algalnu biomasu ili utiču na izmerene parametre. Iako određivanje trofičkog statusa vode nekog vodenog tela ne treba poistovećivati sa samim kvalitetom vode, ono, svakako, predstavlja značajan aspekt istog. Cilj ovog istraživanja bio je određivanje trofičkog statusa jezera Očaga na osnovu Carlson-ovog trofičnog indeksa i ispitivanje veze između izračunatih indeksa za hlorofil a (TSI(CHL)), ukupni fosfor (TSI(TP)) i providnost merenu Secchi diskom (TSI(SD)). Veštačko jezero Očaga nalazi se u blizini Lazarevca i isključivo se koristi za rekreaciju. Ispitivanje vode rađeno je jednom nedeljno tokom jula i avgusta, od 2012. do 2014. godine. Sve analize urađene su u Zavodu za javno zdravlje iz Beograda. Vrednosti dobijenih indeksa (TSIs) varirale su od 41 do 86.25, u ispitanom periodu, a jezero je menjalo status od mezotrofnog, preko eutrofnog do hipereutrofnog, pri čemu su eutrofni uslovi preovladavali. Hipereutrofija je zabeležena tokom avgusta 2013. Godine, kada su bile izmerene i najveće vrednosti sva tri parametra, što je, verovatno, rezultat organskog opterećenja vodenog ekosistema i vremenskih uslova. Prema podacima RHMZ-a, 2013. godina je bila jedna od najtoplijih i najsušnijih godina još od 1951. godine. Nasuprot tome, u avgustu 2014. godine izmerene su najmanje vrednosti svih parametara, što ukazuje na mezotrofne uslove u jezeru te godine. Mezotrofni status jezera je, verovatno, posledica velike količine padavina u prvoj polovini te godine, ali i pražnjenja i ponovnog punjenja jezera nakon majskih poplava

Fractional flow reserve of intermediate lesions on collateral donor coronary arteries after myocardial infarction

Fractional flow reserve (FFR) is the gold standard for the functional assessment of coronary arteries. The aim of this study was to evaluate the relation between angiography, QCA and FFR in borderline lesions on collateral donor coronary arteries. In addition, FFR is compared with the angiographic appearance of collaterals to infarction-related arteries and echocardiographically assessed viability of infarct related the LV wall. In 60 patients with previous IM and occluded IRA, functional assessment of borderline coronary stenosis (30-70% DS) on collaterals donor artery was performed. We have not found statistically significant differences in these parameters between groups with different angiographic appearances of collaterals and different viability of distal myocardium. However, we found higher FFR values in diabetic patients (p=0.018). Higher FFR values in diabetic patients reveal the negative effects of diabetes on collateral growth and myocardial viability

Fractional flow reserve in patients with intermediate values of Duke Treadmill Score and borderline coronary lesions

Despite the wide usage of exercise ECG tests and Duke Treadmill Score (DTS) in clinical practice, no comparison between this scoring system and Fractional Flow Reserve (FFR) has yet been made, particularly in cases of angiographically verified borderline lesions. Thirty patients with single coronary lesions and angiographically assessed borderline stenosis (between 30-70%) and previously calculated intermediate values of DTS between -10 to +4 were examined using FFR. Adequate specificity and sensitivity (0.769 and 0.556, respectively) were in a more narrow range of -0.5 to -10. Sex and age did not have an influence on the DTS values. There was a correlation between the values of FFR and age (r=0.395, p=0.031) and between angiographic assessment of stenosis and quantitative coronary angiography (QCA) (r=0.648, p<0.0001). In the study population, a decision on revascularization could not be based solely on angiographic or QCA assessment of the artery or on the values of DTS

Attitudes of Primary School Teachers Toward Inclusive Education

Background: The aims of our study are related to examining the relevance of teachers' attitudes toward the implementation of inclusive education. In addition, its subject is related to the implications on inclusive education policies, limitations of the existing study along with the recommendations for our future research endeavors. Methods: The research is a cross-sectional study type. The sample included 64 primary school teachers in the lower grades of primary school (grades 1–4), selected by using simple random sampling, in three primary schools on the territory of Belgrade, Serbia in 2021 (26, 17, and 21 primary school teachers). The Questionnaire for Teachers, which was used as a research instrument, was taken from the Master's Thesis Studen Rajke, which was part of the project “Education for the Knowledge Society” at the Institute for Educational Research in Belgrade. Dependent variables measured in the study referred to the attitudes of primary school teachers toward inclusive education. Categorical variables are represented as frequencies and the Chi-square test was used to determine if a distribution of observed frequencies differed from the expected frequencies. Results: One in three teachers (32.8%) thought that inclusion was useful for children with disabilities (29.7%), of them thought that schools did not have the conditions for inclusive education, whereas one in four teachers (25.0%) believed that inclusion was not good. No statistically significant differences were found in the attitudes of professors, when observed in terms of their gender, age and length of service. Conclusion: Investing more resources and time in developing and implementing special education policies can promote successful inclusive education

Socioeconomic inequalities in the use of dental health care among the adult population in Serbia

ObjectivesThe aim of this paper is to assess the association of demografic and socioeconomic determinants with utilization of dental services among Serbian adults.Materials and methodsThe study is a part of the population health research of Serbia, conducted in the period from October to December 2019 by the Institute of Statistics of the Republic of Serbia in cooperation with the Institute of Public Health of Serbia “Dr. Milan JovanovićBatut” and the Ministry of Health of the Republic of Serbia. The research was conducted as a descriptive, cross-sectional analytical study on a representative sample of the population of Serbia. For the purposes of this study, data on the adult population aged 20 years and older were used.ResultsMen were approximately 1.8 times more likely than women to not utilize dental healthcare services (OR = 1.81). The likelihood of not utilizing dental healthcare protection rises with increasing age, reaching its peak within the 65–74 age range (OR = 0.441), after which it declines. Individuals who have experienced marital dissolution due to divorce or the death of a spouse exhibit a higher probability of not utilizing health protection (OR = 1.868). As the level of education and wealth diminishes, the probability of abstaining from health protection increases by 5.8 times among respondents with an elementary school education (OR = 5.852) and 1.7 times among the most economically disadvantaged respondents (OR = 1.745). Regarding inactivity, respondents who are not employed have a 2.6-fold higher likelihood of not utilizing oral health care compared to employed respondents (OR = 2.610).ConclusionThe results suggest that individual sociodemographic factors influence utilization of dental services by Serbian adults and confirmed the existence of socioeconomic disparities

Socially responsible business

Praca recenzowana / Peer-reviewed paperThe work is divided into three parts combined by the idea which points to the fact that irrespective of the kind of business activity and at every level of management social issues appear and should not be disregarded. The first part presents the idea, areas and conditions of using the concept of corporate social responsibility. There is a reference to other concepts such as sustainable development and total quality management. In the second part the authors indicate how corporate social responsibility is applied to selected sectors and specific activities undertaken in enterprises. There is a description of the assumptions, methods of action and outcomes concerning the use of CSR in the sphere of waste management and recycling. Another area presented in this section is the aspects related to the provision of a working environment which does not pose a threat to the employees’ occupational health and safety. The text also refers to the issues of trainings and development. The third part refers to the applications of the idea of CSR at the sectorial, national and international levels. It describes social aspects connected with mining, purchasing, transporting and producing energy using resources. International tensions in the political sphere have a serious impact on this market, and dialogue at different levels should be a significant element of CSR. Two other elaborations in this part are devoted to the analysis of working conditions, culture and organisational behaviour in the countries created after the disintegration of Yugoslavia. In the final part there is a discussion about how the Transatlantic Trade and Investment Partnership currently under negotiation between the EU and the USA corresponds with the concept of CSR. The collection of papers is a result of a cooperation between the authors from Andrzej Frycz Modrzewski Krakow University – Poland and researchers from University of Niš – Faculty of Economics (Project No. 179066 – „Improving the competitiveness of the public and private sector by networking competences in the process of European integration of Serbia”, which is funded of Ministry of Education, Science and Technology development of Republic of Serbia)

Predicting the survival probability of functional neuroendocrine tumors treated with peptide receptor radionuclide therapy: Serbian experience

IntroductionPeptide receptor radionuclide therapy (PRRT) is a treatment option for well-differentiated, somatostatin receptor positive, unresectable or/and metastatic neuroendocrine tumors (NETs). Although high disease control rates seen with PRRT a significant number NET patients have a short progression-free interval, and currently, there is a deficiency of effective biomarkers to pre-identify these patients. This study is aimed at determining the prognostic significance of biomarkers on survival of patients with NETs in initial PRRT treatment.MethodologyWe retrospectively analyzed 51 patients with NETs treated with PRRT at the Department for nuclear medicine, University Clinical Center Kragujevac, Serbia, with a five-year follow-up. Eligible patients with confirmed inoperable NETs, were retrospectively evaluated hematological, blood-based inflammatory markers, biochemical markers and clinical characteristics on disease progression. In accordance with the progression og the disease, the patients were divided into two groups: progression group (n=18) and a non-progression group (n=33). Clinical data were compared between the two groups.ResultsA total of 51 patients (Md=60, age 25-75 years) were treated with PRRT, of whom 29 (56.86%) demonstrated stable disease, 4 (7.84%) demonstrated a partial response, and 14 (27.46%) demonstrated progressive disease and death was recorded in 4 (7.84%) patients. The mean PFS was a 36.22 months (95% CI 30.14-42.29) and the mean OS was 44.68 months (95% CI 37.40-51.97). Univariate logistic regression analysis displayed that age (p&lt;0.05), functional tumors (p&lt;0.05), absolute neutrophil count (p&lt;0.05), neutrophil-lymphocyte ratio-NLR (p&lt;0.05), C-reactive protein-CRP (p&lt;0.05), CRP/Albumin (p&lt;0.05), alanine aminotransferase-ALT (p&lt;0.05), were risk factors for disease progression. Multivariate logistic regression analysis exhibited that functional tumors (p&lt;0.001), age (p&lt;0.05), CRP (p&lt;0.05), and ALT (p&lt;0.05), were independent risk factors for the disease progression in patients with NETs. Tumor functionality was the most powerful prognostic factor. The median PFS (11.86 ± 1.41 vs. 43.38 ± 3.16 months; p=0.001) and OS (21.81 ± 2.70 vs 53.86 ± 3.70, p=0.001) were significantly shorter in patients with functional than non-functional NETs respectively.ConclusionThe study’s results suggest that tumor functionality, and certain biomarkers may serve as prognostic survival indicators for patients with NETs undergoing PRRT. The findings can potentially help to identify patients who are at higher risk of disease progression and tailor treatment strategies accordingly