PENYULUHAN ANEMIA DAN PEMBERIAN TABLET TAMBAH DARAH PADA REMAJA PUTRI (REMATRI) DI SMPN-11 PALANGKA RAYA

Anemia pada remaja putri (rematri) dapat berdampak pada kesehatan dan prestasi di sekolah dan nantinya berisiko anemia saat menjadi ibu hamil yang dapat menyebabkan pertumbuhan dan perkembangan janin yang tidak optimal serta berpotensi menyebabkan komplikasi kehamilan dan persalinan serta kematian ibu dan anak. SMPN-11 Palangka Raya menjadi mitra pengabdian dengan jumlah siswa perempuan lebih banyak dari laki-laki sehingga dilakukan penyuluhan tentang anemia pada remaja putri di SMPN-11 Palngka Raya. Tujuan kegiatan untuk memberikan pengetahuan mengenai anemia, skrining anemia serta pemberiaan Tablet Tambah Darah (TTD) dalam upaya juga menjangkau cakupan pemberian TTD agar lebih merata dan mempersiapkan status gizi agar terhindar dari anemia. Pelaksanaan kegiatan pengabdian masyarakat ini  diikuti oleh 34 peserta. Setelah dilakukan penyuluhan tentang anemia dan tablet tambah darah terdapat peningkatan tingkat pengetahuan yaitu baik 61%, cukup 39% dan kurang 0%. Pada hasil skrining anemia terdapat anemia 5 orang (15%) dan normal 29 orang (85%). Untuk distribusi tablet tambah darah kepada remaja putri terdistribusi 100%.Anemia pada remaja putri (rematri) dapat berdampak pada kesehatan dan prestasi disekolah dan nantinya berisiko anemia saat menjadi ibu hamil yang dapat menyebabkan pertumbuhan dan perkembangan janin yang tidak optimal serta berpotensi menyebabkan komplikasi kehamilan dan persalinan serta kematian ibu dan anak. SMPN-11 Palangka Raya menjadi mitra pengabdian kali ini dengan jumlah siswa perempuan lebih banyak dari laki-laki sehingga dilakukan penyuluhan tentang anemia pada remaja putri di SMPN-11 Palngka Raya. Tujuan kegiatan untuk memberikan pengetahuan mengenai anemia, skrining anemia serta pemberiaan Tablet Tambah Darah (TTD) dalam upaya juga menjangkau cakupan pemberian TTD agar lebih merata dan mempersiapkan status gizi agar terhindar dari anemia. Pelaksanaan kegiatan pengabdian masyarakat ini diikuti oleh 34 peserta. Setelah dilakukan penyuluhan tentang anemia dan tablet tambah darah terdapat peningkatan tingkat pengetahuan yaitu baik 61%, cukup 39% dan kurang 0%. Pada hasil skrining anemia terdapat anemia 5 orang (15%) dan normal 29 orang (85%). Untuk distribusi tablet tambah darah kepada remaja putri terdistribusi 100%

Bioactivity Examination of Uncaria gambir (W.Hunter) Roxb on In Vitro Human Sperm Motility

Globally, 48 million couples experience infertility, where male infertility factors contribute to 50% of cases. Spermatozoa motility is a crucial parameter in assessing male fertility. Antioxidants act as the body's defence against excessive ROS and can be used as a treatment for male infertility. One of the local plants in Central Kalimantan that is potentially rich in antioxidants is Bajakah Kalalawit (Uncaria gambir (W.Hunter) Roxb. However, there is limited research on the bioactivity of Bajakah Kalalawit on spermatozoa in vitro. This study aims to determine the effect of ethanol extract of Uncaria gambir (W. Hunter) Roxb on spermatozoa motility in vitro. Bajakah Kalalawit stems were extracted using a 3x24-hour maceration technique with 96% ethanol. After obtaining the concentrated extract, the secondary metabolite compound content was analyzed through a phytochemical screening. The sample used was in vitro human spermatozoa that were washed and added to Bigger Whitten Whittingham medium, then incubated at 37°C for 1 hour with a 96% ethanol extract of Bajakah Kalalawit at doses of 50ng/ml, 100ng/ml, 500ng/ml, and 1000ng/ml, as well as a control group (Bigger, Whitten & Whittingham medium only). The results showed that the compounds contained in the ethanol extract of Uncaria gambir (W.Hunter) Roxb were terpenoids, flavonoids, phenolics, steroids, saponins, alkaloids, and tannins. Spermatozoa motility significantly increased in the treatment groups starting from doses of 50ng/ml, 100ng/ml, 500ng/ml, and 1000ng/ml compared to the control group. Ethanol extract of Uncaria gambir (W.Hunter) Roxb could increase spermatozoa motility in vitro and succeeded in improving reproductive technology

Literature review : hubungan aktivitas fisik dengan kejadian hipertensi

Hypertension, also known as high blood pressure, is a worldwide health issue. Hypertension is a condition in which the systolic and diastolic blood pressures rise above the usual limit. Lack of physical activity as a risk factor for hypertension needs more attention because this factor is a factor that can be modified with minimal effort and cost.  Understanding the tendency of the relationship between physical activity and the incidence of hypertension. The literature review uses a systematic review approach, data sources, data sources from original articles in the Pubmed.gov and Google Scholar databases with the keywords relationship, physical activity, and hypertension. There were 21 journals that met the inclusion criteria and data quality analysis. Synthesis of data using the SPIDER method. Based on the results of a literature review it was found that in the twenty-four journals analyzed, there were 18 (86%) journals that stated they were related and 3 (14%) stated otherwise. Individuals with lower physical activity tend to have a higher risk of hypertension and the factors that influence it include diet, age, nutritional status, family history of hypertension, smoking to routine health checks.Hypertension, also known as high blood pressure, is a worldwide health issue. Hypertension is a condition in which the systolic and diastolic blood pressures rise above the usual limit. Lack of physical activity as a risk factor for hypertension needs more attention because this factor is a factor that can be modified with minimal effort and cost.  Understanding the tendency of the relationship between physical activity and the incidence of hypertension. The literature review uses a systematic review approach, data sources, data sources from original articles in the Pubmed.gov and Google Scholar databases with the keywords relationship, physical activity, and hypertension. There were 21 journals that met the inclusion criteria and data quality analysis. Synthesis of data using the SPIDER method. Based on the results of a literature review it was found that in the twenty-four journals analyzed, there were 18 (86%) journals that stated they were related and 3 (14%) stated otherwise. Individuals with lower physical activity tend to have a higher risk of hypertension and the factors that influence it include diet, age, nutritional status, family history of hypertension, smoking to routine health checks.

Pengaruh Obat Nyamuk Bakar dan Semprot Terhadap Motilitas Sperma Tikus (Rattus norvegicus)

Gigitan nyamuk dapat membahayakan bagi kesehatan tubuh. Salah satu upaya untuk memberantas nyamuk dalam kehidupan sehari-hari yang umum digunakan adalah dengan menggunakan obat nyamuk. Obat nyamuk terbanyak yang dipakai di masyarakat Indonesia adalah jenis obat nyamuk bakar dan semprot. Kandungan dalam obat nyamuk yaitu berbahan aktif pyrethroid, yang memiliki efek bila dalam jangka waktu lama digunakan dapat menganggu kesehatan tubuh. Salah satunya gangguan terhadap reproduksi pada pria. Oleh sebab itu tujuan penelitian ini untuk mengetahui pengaruh obat nyamuk bakar dan semprot terhadap motilitas sperma tikus galur wistar. Penelitian eksperimental in vivo ini menggunakan desain post-test randomized control design dengan menggunakan 5 kelompok tikus. Kelompok ini terbagi menjadi kontrol, paparan obat nyamuk semprot 5 mL/hari selama 20 hari, paparan obat nyamuk semprot 5 mL/hari selama 35 hari, paparan obat nyamuk bakar 4,5 gr/hari selama 20 hari, paparan obat nyamuk bakar 4,5 gr/hari selama 20 hari. Hasil penelitian secara mikroskopis menunjukkan penurunan motilitas bermakna tidak signifikan pada kelompok tikus yang diberi obat nyamuk semprot dan bakar sejak dipaparkan 20 hari lamanya dan penurunan paling signifikan pada obat nyamuk bakar 35 hari. Obat nyamuk semprot dan bakar yang digunakan rutin dan dalam waktu lama dapat menurunkan motilitas sperma

Pengunaan Bilik Swab Pencegah Risiko Penularan Penyakit Infeksius di RS TNI AD Palangka Raya

WHO merekomendasikan pengambilan spesimen untuk diagnosis COVID-19 pada dua lokasi, yaitu dari saluran napas atas (swab nasofaring atau orofaring) atau saluran napas bawah [sputum, bronchoalveolar lavage, atau aspirat endotrakeal]. Tenaga medis harus memperhatikan keselamatan kerja dengan menggunakan APD (alat pelindung diri) yang tepat karena adanya kontak langsung dengan pasien terduga COVID-19 ketika mengambil sampel yang berisiko tinggi terinfeksi. Kasus COVID-19 di Indonesia meningkat setiap hari dan harga APD melambung tinggi dan terjadi kelangkaan. Mencermati kejadian tersebut maka sebagai wujud implementasi Tri Dharma Perguruan Tinggi, dosen UPR mengambil peran aktif dalam pengabdian masyarakat melalui program dosen pendukung SDM unggul untuk memberikan bilik swab dalam melindungi tenaga medis dari penyebaran infeksi secara langsung. Target dalam pelaksanaan pengabdian masyarakat ini adalah RS TNI-AD Palangka Raya. Metode yang digunakan adalah metode serah-terima alat dan demonstrasi pemakaian sebagai solusi kepada mitra yaitu RS TNI-AD Palangka Raya. Kesimpulan dari program pengabdian ini dengan adanya pemanfaatan bilik swab di RS dapat meminimalisir paparan penyebaran infeksi secara langsung ke tenaga medis serta sebagai alternatif  saat krisis kelangkaan APD level

Photochemical and bioactivity examination of fractionated saluang belum root extract (Lavanga sarmentosa) on in-vitro human sperm motility

Background: Saluang belum (Lavanga sarmentosa) is one of Kalimantan's typical plants, which is as efficacious as a traditional medicine to increase sexual activity and male fertility. Based on previous studies, the content of flavonoid and steroid in 70% ethanol extract of L. sarmentosa were able to affect sperm quality of mice. Studies related to L. sarmentosa are still limited for phytochemical test and their bioactivity on human spermatozoa motility in vitro. Objective: This study is to perform phytochemical tests of compound content in fractionation with eluents of high and low polarity, namely methanol and chloroform, and then to test their bioactivity on the motility of human spermatozoa in vitro. Methods: L. sarmentosa was extracted with 96% ethanol and fractionated by using a vacuum chromatography column with chloroform and methanol as the eluent. Then obtained samples were analysed by a quantitative phytochemical test. The samples used in-vitro human spermatozoa were divided into eleven groups: control group, group administered with L. sarmentosa extract eluent chloroform of 10, 50, 100, 500, and 1000 ng/mL, and same concentration with extract eluent methanol. Furthermore, the sperm motility was analysed by using a Computer Assisted Sperm Analyser (CASA). Results: The methanol and chloroform fraction of L. sarmentosa root extract contained metabolites, namely terpenoids, flavonoids, steroids, alkaloids, saponins, and tannins. The sperm motility increased significantly at the treatment group of the methanol and chloroform fractions compared to the control group. There was a significant difference between the sperm motility incubated with methanol and that with chloroform fraction at concentration 500 and 1000 ng/mL. Conclusion: The results of sperm motility were higher in the methanol fraction than those in the chloroform fraction

Uji Efektivitas Gel Hand Sanitizer Ekstrak Daun Sembung (Blumea balsamifera) Sebagai Antimikroba

AbstrakHand sanitizer merupakan salah satu bahan antiseptik yang yang praktis agar tubuh terhindar dari penyakit yang disebabkan oleh mikroorganisme. Hand sanitizer berbasis alkohol digunakan berlebihan dan terus menerus dapat mengakibatkan iritasi pada kulit. Kandungan yang terdapat dalam bahan alami sebagai alternatif pengganti alkohol antara lain flavonoid dan terpenoid yang terdapat di daun sembung (Blumea balsamifera). Penelitian ini bertujuan untuk mengetahui efektivitas gel hand sanitizer dari ekstrak daun sembung pada berbagai konsentrasi. Serbuk daun sembung diekstraksi secara maserasi menggunakan etanol 70%, kemudian dibuat gel dengan konsentrasi 10%, 15%, dan 20% ditambah carbopol 940, TEA, serta metil paraben. Sediaan gel hand sanitizer dievaluasi melalui uji organoleptis, pH, dan homogenitas selama 4 minggu. Setelah itu, dilakukan pengujian daya antiseptik dan aktivitas antimikroba terhadap Staphylococcus aureus, Escherichia coli, dan Candida albicans. Sediaan gel hand sanitizer ekstrak daun sembung memiliki konsistensi kental, warna hijau kehitaman, aroma khas daun sembung, homogenitas baik, dan nilai pH 6. Sediaan ini juga memiliki daya antiseptik yang baik mampu mengurangi jumlah koloni hingga 95% sama dengan sediaan gel berbasis etanol. Sediaan gel konsentrasi 20% memiliki zona hambat yang sangat kuat terhadap S. aureus dan C. albicans, serta kuat melawan E. coli. Gel hand sanitizer ekstrak Blumea balsamifera menunjukkan aktivitas antimikroba dan dapat digunakan menjadi kandidat agen antimikroba organik alami.Kata kunci: Antimikroba; Antiseptik; Ekstrak Blumea balsamifera; Hand sanitizer  AbstractHand sanitizer is one of antiseptic so that our body avoids diseases caused by microorganism. Hand sanitizer based on ethanol using continuously can cause skin irritation. The secunder metabolit contained in herbal as an alternative to hand sanitizer based ethanol contained flavonoid and terpenoid, are found in sembung leaves (Blumea balsamifera). The aim of this study is to determine the effectiveness of hand sanitizer gel from sembung leaf extract at various concentrations. Sembung leaf was extracted by maceration using 70% ethanol, and then gel was made with concentrations of 10%, 15%, and 20% plus carbopol 940, TEA, methyl paraben. The hand sanitizer gel preparation was evaluated through organoleptic, pH, and homogeneity tests for 4 weeks. After that, antiseptic activity and antimicrobial activity were tested against Staphylococcus aureus, Escherichia coli, and Candida albicans. The hand sanitizer gel preparation of sembung leaf extract has a thick consistency, blackish green color, a distinctive aroma of sembung leaves, good homogeneity, and a pH value of 6. The gel with a concentration of 20% had a very strong zone of inhibition against S. aureus and C. albicans, also strong against E. coli. Blumea balsamifera extract hand sanitizer gel exhibits antimicrobial activity and can be used as a candidate natural organic antimicrobial agent

Validitas Metode Real Time PCR GeneXpert pada Suspek TB Paru BTA Negatif di RSUD Dr. Doris Sylvanus

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Indonesia is one of the developing countries with high TB patients in the world. The most common detection used for TB diagnosis is sputum smear examination. Smear negative pulmonary TB still have a risk of infection and can develop into active. The GeneXpert molecular examination is a rapid diagnosis of TB by the real-time PCR method. The purpose of this study was to assess the validity of GeneXpert in smear-negative pulmonary TB compared to Lowenstein Jensen's culture. The design of this diagnostic test study is a cross-sectional study. The study was conducted on 40 people with smear-negative pulmonary TB suspect patients in Dr. Doris Sylvanus Regional Hospital. Sputum examination was performed with GeneXpert and compared with Lowenstein Jensen culture. The results of GeneXpert validity for diagnosing smear-negative pulmonary TB suspect are sensitivity 81.8%, specificity 96.5%, positive predictive value 90%, negative predictive value 93.3%, and accuracy 92.5%. It was concluded that GeneXpert has sensitivity, specificity, positive predictive value, negative predictive value, and high accuracy as a diagnostic tool in smear-negative pulmonary TB suspects

Pemanfaatan Digital Marketing dalam Pemasaran Briket Arang dari Sekam Padi di Desa Pangkoh Hulu, Kalimantan Tengah

The higher the production produced in agriculture, the higher the waste generated. For example, such as rice, the waste produced is very large, namely rice husks. Rice husk that can be utilized and developed for fuel needs. The method used was preparation, socialization and training which was carried out in Pangkoh Hulu Village, Pandih Batu District, Pulang Pisau Regency, Central Kalimantan. Charcoal briquettes are made from rice husks that are burned, mashed, and filtered until clean then mixed with tapioca flour and water, after which the briquettes are molded and dried to harden for 3-5 days. Digital marketing training in the form of packaging and branding is carried out to obtain added value so that it can be marketed by local residents. The participants who attended were the surrounding community, PKK women, and the X 2022 National Community Service Program students. There were approximately 30 participants who attended the activity and the Pangkoh Hulu Village community received and welcomed the training that we carried out. Making rice husk charcoal briquettes is one way to process rice husk waste so that it can become a selling point that can be marketed.The higher the production produced in agriculture, the higher the waste generated. For example, such as rice, the waste produced is very large, namely rice husks. Rice husk that can be utilized and developed for fuel needs. The method used was preparation, socialization and training which was carried out in Pangkoh Hulu Village, Pandih Batu District, Pulang Pisau Regency, Central Kalimantan. Charcoal briquettes are made from rice husks that are burned, mashed, and filtered until clean then mixed with tapioca flour and water, after which the briquettes are molded and dried to harden for 3-5 days. Digital marketing training in the form of packaging and branding is carried out to obtain added value so that it can be marketed by local residents. The participants who attended were the surrounding community, PKK women, and the X 2022 National Community Service Program students. There were approximately 30 participants who attended the activity and the Pangkoh Hulu Village community received and welcomed the training that we carried out. Making rice husk charcoal briquettes is one way to process rice husk waste so that it can become a selling point that can be markete

Pengaruh Hormon Androgen terhadap Ekspresi Gen CD52 di Epididimis Mencit (Mus musculus)

Androgen has an important role in regulation epididymal sperm maturation  Epididymal sperm maturation is occurs via interactions between sperm and proteins secreted by epididymal genes that are specifically expressed in a region-specific manner. Mice CD52 exhibited expression in all regions in epididymis. However, the regulation of its expression by androgen is needed to be known as a gene candidate that involved in sperm maturation. Objective: This study was aimed to analyze regulation of mice CD52 expression by androgen and a bioinformatics analysis was performed to predict functional domains of CD52. Methods: bioinformatics analysis using Motif Scan. For experiment, mice divided into 5 groups. The groups were control was injected ethanol 0,1 mL/day and others groups were  3, 5, 10, and 15 day used a androgen receptor antagonist, flutamide that dilute in ethanol at a dose of 50 mg/kg/day. And then quantitative real-time RT-PCR was used to analyse expression of CD52 and it’s normalized to Beta actin. Result: CD52 contained a two potential phosphorylation sites for protein kinase C and casein kinase II, N-myristoylation, and N-glycosylation that showed CD52 is secretory protein and predict it’s attached to sperm membrane. Expression of CD52 was decrease about 93% than control. Conclusion: CD52 expression depend on androgen.Keywords:  androgen; epididymis; sperm maturation; expression of CD5