34 research outputs found

    Germination and seedling development in Pistia stratiotes L.

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    This study aimed to describe the post-seminal development, evaluate how the available water, light and temperature influence seed germination and to describe the vegetative propagation by selecting one of the collected plants of Pistia stratiotes. The plant material was collected in a tributary of the Rio Igaraçu, Parnaíba, Piauí State, Brazil. A botanical description of the species was made using individuals collected in the study area. For the germination tests, a total of 1400 seeds were harvested and three experiments were conducted, varying the amount of available water, light and temperature. The results showed that the highest percentage of germination is occurred with seeds pre-washed with distilled water, sown on filter paper with abundant water (enough to form a sheet of water) and exposed to alternating light at an average temperature of 37°C. Germination began on the fourth day after sowing, marked by the appearance of the cataphyll. After 22 days, the seedling stage was completed. Vegetative propagation of this species is efficient and fast. In 50 days, a total of 134 new vegetative shoots were recorded in just one individual. The results showed that the germination rate is related to the amount of light and temperature

    Antioxidant, Antinociceptive, and Anti-inflammatory Properties of the Ethanolic Extract of Combretum duarteanum in Rodents

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    This is a copy of an article published in the Journal of Medicinal Food© 2011 - copyright Mary Ann Liebert, Inc.; Journal of Medicinal Food is available online at: http://online.liebertpub.comThe antioxidant, antinociceptive, and anti-inflammatory activities of the ethanolic extract from leaves of Combretum duarteanum (EEC) were assessed in rodents through in vitro tests. The antioxidant activity was investigated by using thiobarbituric acid reactive species (TBARS), hydroxyl radical–scavenging, and scavenging activity of nitric oxide assays. The antinociceptive activity was investigated by using acetic acid–induced writhing, formalin, and hot-plate tests in mice. The anti-inflammatory activity was assessed in rats by using the carrageenan-induced hind-paw edema test and arachidonic acid–induced paw edema test. EEC possesses a strong antioxidant potential according to the TBARS, nitric oxide, and hydroxyl radical–scavenging assays; it also presented scavenger activity in all in vitro tests. After intraperitoneal injection, EEC (100, 200, and 400 mg/kg) significantly reduced the number of writhes (38.1%, 90.6%, and 97.8%, respectively) in a writhing test and the number of paw licks during phase 1 (30.5% and 69.5%, higher doses) and phase 2 (38.1%, 90.6%, and 97.8%, all doses) of a formalin test when compared with the control group. Naloxone (1.5 mg/kg, intraperito- neally) antagonized the antinociceptive action of EEC (400 mg/kg), and this finding suggests participation of the opioid system. Administration of 200 and 400 mg/kg (intraperitoneally) of EEC exhibited an anti-inflammatory activity in the carrageenin test, which was based on interference with prostaglandin synthesis. This finding was confirmed by the arachidonic acid test. Together, these results indicate that properties of EEC might be further explored in the search for newer tools to treat painful inflammatory conditions, including those related to pro-oxidant states

    Integrative Community Therapy And Its Meaning For Student Life

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    Objective: Understanding the meaning of ICT (Integrative Community Therapy) in the life of students participating in the Extension Project “O desabrochar de si: a TCI no Centro de Atenção Psicossocial”. Method: It is an exploratory and descriptive study of qualitative approach that sought to understand the phenomenon in question using an instrument of semi-structured interview applied to students of the Education and Health Center at the Campina Grande Federal University (UFCG), Cuite campus, in the state of Paraiba. Results: The results found enabled the construction of the following categories: Knowing the (un)known: the meeting with and approach to ICT; ICT and its mobilizing potential; and the following subcategories: Revealing a cycle of discoveries; Unveiling experiences for life. This study revealed that ICT has a relevant impact, bringing forth positive changes in the life of students in question. Conclusion: It can be said that the participants expressed satisfaction and personal changes, since ICT availed at rescuing essential values for their lives, favoring the discovery and the finding of strengths to face the adversities of daily life. The students found in the Extension Project and in ICT a source of support for personal improvement, besides giving the opportunity for the creation and strengthening of bonds between the team, community and professors

    TECNOLOGIAS EDUCATIVAS NO CONTEXTO DA ASSISTÊNCIA À ATENÇÃO PRIMÁRIA: UMA REFLEXÃO SOB A ÓTICA DE PAULO FREIRE

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    Educational technologies are devices that enable the consideration of the singularities of the subjects involved in the work process. Therefore, it is necessary that health professionals be aware of these technologies in order to improve the quality of the care they provide. The objective was to contribute to critical reflection on the adherence to educational technologies in health care by the multiprofessional team in the context of primary care. It was based on an integrative review, with qualitative subsidy and reflexive bias, when the data were interpreted from the critical view of the researchers and in the light of Paulo Freire's theoretical subsidy about the educative practice. The electronic bibliographic bases LILACS and BDENF were used, accessed through the advanced search in the Virtual Health Library. The inclusion criteria were: primary studies, available in full, published between the years 2017 and 2021, in Portuguese, English and Spanish, and that addressed the theme. Twelve articles were analyzed. It was found that primary care uses some types of light technologies such as: qualified listening, bonding, welcoming, educational actions in health and accountability. In Paulo Freire's reflective approach to inclusive education, which can be achieved through educational technologies that increase the access to health actions offered to the population and induce the integrality of care. In this scenario, the adherence to these tools enables the active participation of the professional as an educator in the learning process, providing the continuous development of the assistance skills of both the patient and the health professionals.Las tecnologías educativas son dispositivos que permiten la consideración de las singularidades de los sujetos involucrados en el proceso de trabajo, por lo que es necesario sensibilizar a los profesionales de la salud sobre estas tecnologías con el fin de mejorar la calidad de la atención producida por ellos. El objetivo fue contribuir a la reflexión crítica en el apoyo de las tecnologías educativas en la atención sanitaria por parte del equipo multidisciplinar en el contexto de la atención primaria. Se basó en una revisión integradora, con apoyo cualitativo y sesgo reflexivo, cuando los datos fueron interpretados desde la perspectiva crítica de los investigadores y a la luz del apoyo teórico de Paulo Freire sobre la práctica educativa. Se utilizaron las bases de datos bibliográficas electrónicas: LILACS y BDENF, a las que se accedió a través de la búsqueda avanzada en la Biblioteca Virtual en Salud (BVS). Los criterios de inclusión fueron: estudios primarios, disponibles en su totalidad, publicados entre 2017 y 2021, en los idiomas portugués, inglés y español que abordaron el tema. Se analizaron 12 artículos. Se encontró que la atención primaria utiliza algunos tipos de tecnologías de luz como: escucha calificada, vinculación, acogida, acciones educativas en salud y rendición de cuentas. En el aspecto reflexivo de Paulo Freire, en el sesgo de la educación inclusiva, que se puede lograr a través de tecnologías educativas que han aumentado el acceso a las acciones de salud ofrecidas a la población e inducen la integralidad de la atención.Este estudo buscou contribuir com a reflexão crítica na adesão das tecnologias educativas na assistência à saúde pela equipe multiprofissional no contexto da atenção primaria. Baseou-se de uma revisão integrativa, com subsídio qualitativa e viés reflexivo, quando os dados foram interpretados a partir do olhar crítico dos pesquisadores e à luz do subsídio teórico de Paulo Freire sobre a prática educativa. Trata-se de uma revisão integrativa com viés reflexivo viés reflexivo, a partir do olhar crítico dos pesquisadores e à luz do subsídio teórico de Paulo Freire sobre a prática educativa. As buscas foram realizadas nas bases de dados: LILACS e BDENF, acessadas por meio da busca avançada na BVS. Utilizou-se os descritores associados pelos operadores booleanos: “Atenção Primaria” AND Tecnologia OR Saúde, incluindo, estudos de reflexão, teses, dissertações e artigos originais disponíveis na íntegra no formato on-line, publicados na íntegra entre os anos de 2015 a 2021.De acordo com os critérios de elegibilidade, foram inclusos 12 artigos neste estudo. Nessa perspectiva, a partir da ótica reflexiva de Paulo Freire, no viés da educação inclusiva, que pode ser alcançada através das tecnologias educativas que aumentaram o acesso às ações de saúde oferecidas à população e induzem a integralidade da assistência. Portanto, a adesão dessas ferramentas possibilita a participação ativa do profissional como educador no processo da aprendizagem, propiciando o desenvolvimento contínuo das habilidades assistências tanto do paciente quanto dos profissionais da área de saúde

    TECNOLOGIAS EDUCATIVAS NO CONTEXTO DA ASSISTÊNCIA À ATENÇÃO PRIMÁRIA: UMA REFLEXÃO SOB A ÓTICA DE PAULO FREIRE

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    Educational technologies are devices that enable the consideration of the singularities of the subjects involved in the work process. Therefore, it is necessary that health professionals be aware of these technologies in order to improve the quality of the care they provide. The objective was to contribute to critical reflection on the adherence to educational technologies in health care by the multiprofessional team in the context of primary care. It was based on an integrative review, with qualitative subsidy and reflexive bias, when the data were interpreted from the critical view of the researchers and in the light of Paulo Freire's theoretical subsidy about the educative practice. The electronic bibliographic bases LILACS and BDENF were used, accessed through the advanced search in the Virtual Health Library. The inclusion criteria were: primary studies, available in full, published between the years 2017 and 2021, in Portuguese, English and Spanish, and that addressed the theme. Twelve articles were analyzed. It was found that primary care uses some types of light technologies such as: qualified listening, bonding, welcoming, educational actions in health and accountability. In Paulo Freire's reflective approach to inclusive education, which can be achieved through educational technologies that increase the access to health actions offered to the population and induce the integrality of care. In this scenario, the adherence to these tools enables the active participation of the professional as an educator in the learning process, providing the continuous development of the assistance skills of both the patient and the health professionals.Las tecnologías educativas son dispositivos que permiten la consideración de las singularidades de los sujetos involucrados en el proceso de trabajo, por lo que es necesario sensibilizar a los profesionales de la salud sobre estas tecnologías con el fin de mejorar la calidad de la atención producida por ellos. El objetivo fue contribuir a la reflexión crítica en el apoyo de las tecnologías educativas en la atención sanitaria por parte del equipo multidisciplinar en el contexto de la atención primaria. Se basó en una revisión integradora, con apoyo cualitativo y sesgo reflexivo, cuando los datos fueron interpretados desde la perspectiva crítica de los investigadores y a la luz del apoyo teórico de Paulo Freire sobre la práctica educativa. Se utilizaron las bases de datos bibliográficas electrónicas: LILACS y BDENF, a las que se accedió a través de la búsqueda avanzada en la Biblioteca Virtual en Salud (BVS). Los criterios de inclusión fueron: estudios primarios, disponibles en su totalidad, publicados entre 2017 y 2021, en los idiomas portugués, inglés y español que abordaron el tema. Se analizaron 12 artículos. Se encontró que la atención primaria utiliza algunos tipos de tecnologías de luz como: escucha calificada, vinculación, acogida, acciones educativas en salud y rendición de cuentas. En el aspecto reflexivo de Paulo Freire, en el sesgo de la educación inclusiva, que se puede lograr a través de tecnologías educativas que han aumentado el acceso a las acciones de salud ofrecidas a la población e inducen la integralidad de la atención.Este estudo buscou contribuir com a reflexão crítica na adesão das tecnologias educativas na assistência à saúde pela equipe multiprofissional no contexto da atenção primaria. Baseou-se de uma revisão integrativa, com subsídio qualitativa e viés reflexivo, quando os dados foram interpretados a partir do olhar crítico dos pesquisadores e à luz do subsídio teórico de Paulo Freire sobre a prática educativa. Trata-se de uma revisão integrativa com viés reflexivo viés reflexivo, a partir do olhar crítico dos pesquisadores e à luz do subsídio teórico de Paulo Freire sobre a prática educativa. As buscas foram realizadas nas bases de dados: LILACS e BDENF, acessadas por meio da busca avançada na BVS. Utilizou-se os descritores associados pelos operadores booleanos: “Atenção Primaria” AND Tecnologia OR Saúde, incluindo, estudos de reflexão, teses, dissertações e artigos originais disponíveis na íntegra no formato on-line, publicados na íntegra entre os anos de 2015 a 2021.De acordo com os critérios de elegibilidade, foram inclusos 12 artigos neste estudo. Nessa perspectiva, a partir da ótica reflexiva de Paulo Freire, no viés da educação inclusiva, que pode ser alcançada através das tecnologias educativas que aumentaram o acesso às ações de saúde oferecidas à população e induzem a integralidade da assistência. Portanto, a adesão dessas ferramentas possibilita a participação ativa do profissional como educador no processo da aprendizagem, propiciando o desenvolvimento contínuo das habilidades assistências tanto do paciente quanto dos profissionais da área de saúde

    Hemodynamic and inflammatory response elements and their prognostic role in the context of surgical treatment in pediatric patients with congenital heart disease and pulmonary hypertension

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    Alterações estruturais e funcionais estão presentes na circulação pulmonar em pacientes com comunicações cardíacas congênitas. A inflamação tem um papel primordial no remodelamento vascular pulmonar que acompanha esta condição. Todo este processo tem implicação na indicação cirúrgica e no padrão hemodinâmico pulmonar no período pós-operatório imediato e tardio. Informações sobre a relação entre hemodinâmica pulmonar pós-operatória, inflamação e desfechos de curto, médio e longo prazo, em pacientes pediátricos submetidos a cirurgia, são escassas. Desta forma, este estudo teve por objetivo investigar em pacientes pediátricos, no contexto do tratamento cirúrgico, possíveis relações entre hemodinâmica pulmonar, elementos de resposta inflamatória e eventos clínicos no período pós-operatório. Além disso, identificar possíveis preditores de pressão arterial pulmonar persistentemente alterada após a alta hospitalar. MÉTODOS: Estudo do tipo prospectivo, de coorte, com observações de caráter longitudinal, envolvendo a comparação entre grupos hemodinâmicos. A coleta de dados ocorreu entre os anos de 2016 e 2018. O protocolo do estudo foi aprovado pela Comissão de Ética para Análise de Projetos de Pesquisa (CAPPesq 4324/15/151) e teve o suporte financeiro da Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP Processo nº 2016/21587-5). Foram incluídas 40 crianças. A idade variou entre quatro e 35 meses (mediana de 11 meses), sendo 63% com síndrome de Down, todas submetidas ao tratamento cirúrgico de correção do defeito do septo átrio ventricular (60%) ou comunicação interventricular (40%). A coleta dos dados clínicos, cirúrgicos, laboratoriais e hemodinâmicos ocorreu durante o período de internação. A ecocardiografia transtorácica foi realizada seis meses após a correção cirúrgica para determinação não invasiva da pressão arterial pulmonar. A resposta inflamatória foi avaliada pela análise de 36 marcadores séricos específicos, na condição basal, quatro e 24 horas após o término da circulação extracorpórea, além de elementos celulares e humorais pesquisados habitualmente na rotina assistencial. No período pós-operatório, os pacientes ficaram monitorizados com cateter em artéria pulmonar e pressão arterial sistêmica invasiva por 72 horas. A razão entre as pressões médias arteriais pulmonar e sistêmica foi mensurada no período pós-operatório e a média dos quatro primeiros valores (PMAP/PMASPOI) com medidas obtidas a cada duas horas na unidade de cuidados intensivos, foi usada para categorizar os pacientes em dois grupos: PMAP/PMASPOI 0,40 (18 pacientes). Eventos Cardiorrespiratórios e Hemodinâmicos Relevantes (ECRHR) foram definidos antes do início do projeto como uma conjunção de alterações cardiocirculatórias e respiratórias importantes que tivessem início com o aumento da pressão pulmonar. RESULTADOS: A situação hemodinâmica pulmonar observada nas primeiras seis horas após a cirurgia (PMAP/PMASPOI) correlacionou com os dados obtidos no centro cirúrgico (p 0,40 comparativamente ao grupo PMAP/PMASPOI 0,40 e o nível sérico elevado da proteína MIF no período pós-operatório imediato mostraram-se preditores de ECRHR (hazard ratio e IC 95%, respectivamente, 5,07 (1,10 - 23,45), p=0,038, e 3,29 (1,38 7,88), p 0,40 foi preditora de pressão sistólica arterial pulmonar elevada (> 30 mmHg, pela ecocardiografia) seis meses após a cirurgia (hazard ratio 7,50 (1,72 32,80), p=0,007). CONCLUSÕES: O padrão de comportamento hemodinâmico pulmonar foi identificado no início do período pós-operatório e correlacionou-se com parâmetros hemodinâmicos do centro cirúrgico ao final da circulação extracorpórea. PMAP/PMASPOI > 0,40 correlacionou-se com níveis circulantes de marcadores inflamatórios mensurados tanto no período pré como no pós-operatório imediato: IL-6, IL1-RA, G-CSF, IL-21 e volume plaquetário médio. O comportamento hemodinâmico inicial e o nível da proteína MIF na quarta hora correlacionam-se com Eventos Cardiorrespiratórios Hemodinâmicos Relevantes. A evolução da pressão arterial pulmonar seis meses após o tratamento cirúrgico pode ser prevista a partir do comportamento hemodinâmico pulmonar no período pós-operatório imediatoStructural and functional changes are present in the pulmonary circulation in patients with congenital cardiac communications. Inflammation, which comes alongside with this condition, plays a major role in pulmonary vascular remodeling. This process has implications for the surgical indication and for the pulmonary hemodynamic performance, both in the immediate and late postoperative period. There is currently little information on the correlation among postoperative pulmonary hemodynamics, inflammation, and outcomes in pediatric patients undergoing surgery. Thus, this study aimed at investigating relationships among pulmonary hemodynamics, elements of inflammatory response, and clinical events in the postoperative period in pediatric patients undergoing surgical treatment. Furthermore, this study also aimed at identifying possible predictors of late persistent changes in pulmonary arterial pressure after hospital discharge. METHODS: Prospective, cohort study with longitudinal observations involving comparison between hemodynamic groups. Data were collected from November 2016 to October 2018. The study protocol was approved by the Ethics Committee for Analysis of Research Projects (CAPPesq 4324/15/151) with the financial support of the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP - Process nº 2016 / 21587-5). Forty children were included. The age ranged from four to 35 months (median 11 months), 63% of whom had Down syndrome. They underwent surgical treatment to correct either the atrioventricular septal defect (60%) or the ventricular septal defect (40%). The collection of clinical, surgical, laboratory, and hemodynamic data occurred during the hospitalization period. Transthoracic echocardiography was performed six months after surgical correction for noninvasive determination of pulmonary arterial pressure. The inflammatory response was assessed at baseline (before surgical procedure) and 4 hours and 24 hours after the end of cardiopulmonary bypass - by the analysis of 36 specific serum markers. In addition, cellular and humoral elements were also investigated as part of the hospital routine. Postoperatively, pulmonary and systemic pressure were monitored with invasive indwelling catheters for 72 hours. The pulmonary/systemic mean arterial pressure ratio was also obtained. The mean of the first four values (PMAP/PMASPOI), with measurements obtained every two hours in the ICU, was used to categorize the patients into two groups: PMAP/PMASPOI 0.40 (18 patients). The relevant cardiorespiratory and hemodynamic events were defined prior to the study as a composite of major cardiocirculatory and respiratory disturbances. RESULTS: The pulmonary hemodynamic performance observed in the first six hours after surgery (PMAP/PMASPOI) was correlated with data obtained in the operating room (p 0.40: G-CSF (p=0.040), IL1-RA (p=0.020), IL-6 (p=0.003), IL-21 (p=0.047) and mean platelet volume (p=0.018). The PMAP/PMASPOI > 0.40 condition and the elevated serum level of the MIF protein in the immediate postoperative period were shown as predictors of relevant cardiorespiratory and hemodynamic events (hazard ratio with 95% CI, respectively, 5.07 (1.10 - 23.45), p=0.038, and 3.29 (1.38 - 7.88), p 0.40 was a predictor of elevated pulmonary arterial systolic pressure (> 30 mmHg, by echocardiography) six months after surgery (hazard ratio 7.50 (1.72 - 32.80), p=0.007). CONCLUSIONS: The pattern of pulmonary hemodynamic performance was identified at the beginning of the postoperative period and correlated with hemodynamic parameters in the operating room at the end of cardiopulmonary bypass. PMAP/PMASPOI > 0.40 was correlated with circulating levels of inflammatory markers measured both before surgery and in the immediate postoperative period as IL-6, IL1-RA, G-CSF, IL-21, and mean platelet volume. The initial postoperative hemodynamic performance and the level of the MIF protein four hours postoperatively were correlated with relevant hemodynamic and cardiorespiratory events. The evolution of pulmonary arterial pressure six months after surgery can be predicted by taking into consideration the pulmonary hemodynamic performance in the immediate postoperative perio

    Ocorrência de Crenea maritima (Lythraceae) para o Delta do Parnaíba, Brasil

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    ResumoO gênero Crenea é composto por duas espécies, Crenea maritimae C. patentinervis, restrito às costas e estuários do norte da América do Sul da Colômbia ao Pará, no Brasil. Estudos taxonômicos tratando exclusivamente de Creneasão restritos. Este trabalho teve por objetivo divulgar a ocorrência de Crenea maritimapara o Delta do Rio Parnaíba (Piauí e Maranhão), assim como caracterizar sua morfologia, taxonomia e condições ecológicas. As ilustrações foram baseadas nos principais caracteres diagnósticos das amostras coletadas
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