Baryon Destruction by Asymmetric Dark Matter

We investigate new and unusual signals that arise in theories where dark matter is asymmetric and carries a net antibaryon number, as may occur when the dark matter abundance is linked to the baryon abundance. Antibaryonic dark matter can cause {\it induced nucleon decay} by annihilating visible baryons through inelastic scattering. These processes lead to an effective nucleon lifetime of 10^{29}-10^{32} years in terrestrial nucleon decay experiments, if baryon number transfer between visible and dark sectors arises through new physics at the weak scale. The possibility of induced nucleon decay motivates a novel approach for direct detection of cosmic dark matter in nucleon decay experiments. Monojet searches (and related signatures) at hadron colliders also provide a complementary probe of weak-scale dark-matter--induced baryon number violation. Finally, we discuss the effects of baryon-destroying dark matter on stellar systems and show that it can be consistent with existing observations.Comment: 26 pages, 6 figure

Dark Matter Antibaryons from a Supersymmetric Hidden Sector

The cosmological origin of both dark and baryonic matter can be explained through a unified mechanism called hylogenesis where baryon and antibaryon number are divided between the visible sector and a GeV-scale hidden sector, while the Universe remains net baryon symmetric. The "missing" antibaryons, in the form of exotic hidden states, are the dark matter. We study model-building, cosmological, and phenomenological aspects of this scenario within the framework of supersymmetry, which naturally stabilizes the light hidden sector and electroweak mass scales. Inelastic dark matter scattering on visible matter destroys nucleons, and nucleon decay searches offer a novel avenue for the direct detection of the hidden antibaryonic dark matter sea.Comment: 33 pages, 10 figures. Minor changes to match published versio

Cosmic 21-cm Delensing of Microwave Background Polarization and the Minimum Detectable Energy Scale of Inflation

The curl (B) modes of cosmic microwave background (CMB) polarization anisotropies are a unique probe of the primordial background of inflationary gravitational waves (IGWs). Unfortunately, the B-mode polarization anisotropies generated by gravitational waves at recombination are confused with those generated by the mixing of gradient-mode (E-mode) and B-mode polarization anisotropies as CMB photons propagate through the Universe and are gravitationally lensed. We describe here a method for delensing CMB polarization anisotropies using observations of anisotropies in the cosmic 21-cm radiation emitted or absorbed by neutral hydrogen atoms at redshifts 10 to 200. While the detection of cosmic 21-cm anisotropies at high resolution is challenging, a combined study with a relatively low-resolution (but high-sensitivity) CMB polarization experiment could probe inflationary energy scales well below the Grand Unified Theory (GUT) scale of 10^{16} GeV -- constraining models with energy scales below 10^{15} GeV (the detectable limit derived from CMB observations alone). The ultimate theoretical limit to the detectable inflationary energy scale via this method may be as low as 3 \times 10^{14} GeV.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let

Measuring the Primordial Deuterium Abundance During the Cosmic Dark Ages

We discuss how measurements of fluctuations in the absorption of cosmic microwave background (CMB) photons by neutral gas during the cosmic dark ages, at redshifts z ~ 7--200, could reveal the primordial deuterium abundance of the Universe. The strength of the cross-correlation of brightness-temperature fluctuations due to resonant absorption of CMB photons in the 21-cm line of neutral hydrogen with those due to resonant absorption of CMB photons in the 92-cm line of neutral deuterium is proportional to the fossil deuterium to hydrogen ratio [D/H] fixed during big bang nucleosynthesis (BBN). Although technically challenging, this measurement could provide the cleanest possible determination of [D/H], free from contamination by structure formation processes at lower redshifts, and has the potential to improve BBN constraints to the baryon density of the Universe \Omega_{b} h^2. We also present our results for the thermal spin-change cross-section for deuterium-hydrogen scattering, which may be useful in a more general context than we describe here.Comment: 4 pages, 3 figures, submitted to Phys. Rev. Let

Cosmological Signatures of Interacting Neutrinos

We investigate signatures of neutrino scattering in the Cosmic Microwave Background (CMB) and matter power spectra, and the extent to which present cosmological data can distinguish between a free streaming or tightly coupled fluid of neutrinos. If neutrinos have strong non-standard interactions, for example, through the coupling of neutrinos to a light boson, they may be kept in equilibrium until late times. We show how the power spectra for these models differ from more conventional neutrino scenarios, and use CMB and large scale structure data to constrain these models. CMB polarization data improves the constraints on the number of massless neutrinos, while the Lyman--$\alpha$ power spectrum improves the limits on the neutrino mass. Neutrino mass limits depend strongly on whether some or all of the neutrino species interact and annihilate. The present data can accommodate a number of tightly-coupled relativistic degrees of freedom, and none of the interacting-neutrino scenarios considered are ruled out by current data -- although considerations regarding the age of the Universe disfavor a model with three annihilating neutrinos with very large neutrino masses.Comment: 17 pages, 14 figures, minor changes and references added, published in Phys. Rev.

Polarizing Bubble Collisions

We predict the polarization of cosmic microwave background (CMB) photons that results from a cosmic bubble collision. The polarization is purely E-mode, symmetric around the axis pointing towards the collision bubble, and has several salient features in its radial dependence that can help distinguish it from a more conventional explanation for unusually cold or hot features in the CMB sky. The anomalous "cold spot" detected by the Wilkinson Microwave Anisotropy Probe (WMAP) satellite is a candidate for a feature produced by such a collision, and the Planck satellite and other proposed surveys will measure the polarization on it in the near future. The detection of such a collision would provide compelling evidence for the string theory landscape.Comment: Published version. 15 pages, 8 figure

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

Chronic wasting disease (CWD) is a prion disease that affects free-ranging and captive cervids, including mule deer, white-tailed deer, Rocky Mountain elk and moose. CWD-infected cervids have been reported in 14 USA states, two Canadian provinces and in South Korea. The possibility of a zoonotic transmission of CWD prions via diet is of particular concern in North America where hunting of cervids is a popular sport. To investigate the potential public health risks posed by CWD prions, we have investigated whether intracerebral inoculation of brain and spinal cord from CWD-infected mule deer transmits prion infection to transgenic mice overexpressing human prion protein with methionine or valine at polymorphic residue 129. These transgenic mice have been utilized in extensive transmission studies of human and animal prion disease and are susceptible to BSE and vCJD prions, allowing comparison with CWD. Here, we show that these mice proved entirely resistant to infection with mule deer CWD prions arguing that the transmission barrier associated with this prion strain/host combination is greater than that observed with classical BSE prions. However, it is possible that CWD may be caused by multiple prion strains. Further studies will be required to evaluate the transmission properties of distinct cervid prion strains as they are characterized

Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies

<p>Abstract</p> <p>Background</p> <p>Collection of buccal cells from saliva for DNA extraction offers a less invasive and convenient alternative to venipuncture blood collection that may increase participation in genetic epidemiologic studies. However, dried blood spot collection, which is also a convenient method, offers a means of collecting peripheral blood samples from which analytes in addition to DNA can be obtained.</p> <p>Methods</p> <p>To determine if offering blood spot collection would increase participation in genetic epidemiologic studies, we conducted a study of collecting dried blood spot cards by mail from a sample of female cancer cases (n = 134) and controls (n = 256) who were previously selected for a breast cancer genetics study and declined to provide a venipuncture blood sample. Participants were also randomized to receive either a $2.00 bill or no incentive with the blood spot collection kits.</p> <p>Results</p> <p>The average time between the venipuncture sample refusal and recruitment for the blood spot collection was 4.4 years. Thirty-seven percent of cases and 28$2.00 incentive vs. 26% for no incentive, p = 0.6), it was significantly associated with participation among the breast cancer cases (48% vs. 27%, respectively, p = 0.01). There did not appear to be any bias in response since no differences between cases and controls and incentive groups were observed when examining several demographic, work history and radiation exposure variables.</p> <p>Conclusion</p> <p>This study demonstrates that collection of dried blood spot cards in addition to venipuncture blood samples may be a feasible method to increase participation in genetic case-control studies.</p