1,878 research outputs found
Effects of bike lane features on cyclists’ exposure to black carbon and ultrafine particles
The flare origin of Forbush decreases not associated with solar flares on the visible hemisphere of the Sun
Investigations have shown that Forbush decreases (Fds) are produced by the propagation into the interplanetary space of a strong perturbation originating from a solar flare (Sf) accompanied by Type IV radioemission. As the front of the perturbation propagates into the interplanetary space, the region in which the galactic cosmic rays are modulated (Fd-modulated region) rotates westward with the Sun and is generally included between two boundary streams; therefore the Fds not associated with observed type IV Sfs (N.Ass.Fds) are likely to be produced by type IV Sfs occurred on the Sun's backside: these vents can be observed when the Earth crosses the corotating Western boundary of the modulated region
Anomalous short-term increases in the galactic cosmic ray intensity: Are they related to the interplanetary magnetic cloud-like structures?
Thirty-one short-term increases (time duration 24 hours and amplitude up to 5%) in the galactic cosmic ray intensity, occurring inside Forbush decreases events, have been identified over the period 1966 - 1977. These increases are highly anisotropic and occur after the compression region following the shock; the interplanetary medium is characterized by intense ( 10 nT) and higly fluctuating magnetic field B, high velocity, low density and temperature (flare ejecta piston?). These B-fluctuations seem to be ordered variations which could be representative of magnetic clouds. Also the large cosmic ray increase occurring on 17-18 September 1979, belongs to this category of events
Suggestions for improving the efficiency of ground-based neutron monitors for detecting solar neutrons
On the occasion of the June 3, 1982 intense gamma-ray solar flare a significant increase in counting rate due to solar neutrons was observed by the neutron monitors of Junsfraujoch and Lomnicky Stit located at middle latitudes and high altitudes. In spite of a larger detector employed and of the smaller solar zenith angle, the amplitude of the same event observed at Rome was much smaller and the statistical fluctuations of the salactic cosmic ray background higher than the ones registered at the two mountain stations, because of the greater atmospheric depth at which the Rome monitor is located. The effeciency for detecting a solar neutron event by a NM-64 monitor as a function of the Sun zenith angle, atmospheric depth and threshold rigidity of the station was studied
Pragmatic language disorder in Parkinson's disease and the potential effect of cognitive reserve
It is known that patients with Parkinson\u2019s Disease (PD) may show deficits in several areas of cognition, including speech and language abilities. One domain of particular interest is pragmatics, which refers to the capacity of using language in context for a successful communication. Several studies showed that some specific aspects of pragmatics \u2013 both in production and in comprehension \u2013 might be impaired in patients with PD. However, a clear picture of pragmatic abilities in PD is still missing, as most of the existing studies focused on specific aspects of the pragmatic competence rather than on sketching a complete pragmatic profile. Moreover, little is known on the potential role of protective factors in compensating the decline of communicative skills as the disease progresses. The present study has two aims: (1) to provide a complete picture of pragmatic abilities in patients with PD, by using a comprehensive battery (Assessment of Pragmatic Abilities and Cognitive Substrates, APACS) and by investigating the relationship with other aspects of cognitive functioning (e.g., working memory and Theory of Mind) and (2) to investigate whether Cognitive Reserve, i.e., the resilience to cognitive impairment provided by life experiences and activities, may compensate for the progressive pragmatic deficits in PD. We found that patients with PD, compared to healthy matched controls, had worse performance in discourse production and in the description of scenes, and that these impairments were tightly correlated with the severity of motor impairment, suggesting reduced intentionality of engaging in a communicative exchange. Patients with PD showed also an impairment in comprehending texts and humor, suggesting a problem in inferring from stories, which was related to general cognitive impairment. Notably, we did not find any significant difference between patients and controls in figurative language comprehension, a domain that is commonly impaired in other neurodegenerative diseases. This might be indicative of a specific profile of pragmatic impairment in patients with PD, worth of further investigation. Finally, Cognitive Reserve measures showed a high degree of association with pragmatic comprehension abilities, suggesting that the modification of life-styles could be a good candidate for compensating the possible problems in understanding the pragmatic aspects of language experienced by patients with PD
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Detection and isolation of circulating tumor cells with single-cell resolution: A successful lab-on-a-chip device
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.This paper presents the unique features of DEPArray™ an automated system enabling image-based cell sorting with single-cell resolution and describes its potential application in the field of oncology
Antepartum Fetal Monitoring through a Wearable System and a Mobile Application
Prenatal monitoring of Fetal Heart Rate (FHR) is crucial for the prevention of fetal pathologies and unfavorable deliveries. However, the most commonly used Cardiotocographic exam can be performed only in hospital-like structures and requires the supervision of expert personnel. For this reason, a wearable system able to continuously monitor FHR would be a noticeable step towards a personalized and remote pregnancy care. Thanks to textile electrodes, miniaturized electronics, and smart devices like smartphones and tablets, we developed a wearable integrated system for everyday fetal monitoring during the last weeks of pregnancy. Pregnant women at home can use it without the need for any external support by clinicians. The transmission of FHR to a specialized medical center allows its remote analysis, exploiting advanced algorithms running on high-performance hardware able to obtain the best classification of the fetal condition. The system has been tested on a limited set of pregnant women whose fetal electrocardiogram recordings were acquired and classified, yielding an overall score for both accuracy and sensitivity over 90%. This novel approach can open a new perspective on the continuous monitoring of fetus development by enhancing the performance of regular examinations, making treatments really personalized, and reducing hospitalization or ambulatory visits. Keywords: tele-monitoring; wearable devices; fetal heart rate; telemedicin
Monitoring Fetal Heart Rate during Pregnancy: Contributions from Advanced Signal Processing and Wearable Technology
Monitoring procedures are the basis to evaluate the clinical state of patients and to assess changes in their conditions, thus providing necessary interventions in time. Both these two objectives can be achieved by integrating technological development with methodological tools, thus allowing accurate classification and extraction of useful diagnostic information. The paper is focused on monitoring procedures applied to fetal heart rate variability (FHRV) signals, collected during pregnancy, in order to assess fetal well-being. The use of linear time and frequency techniques as well as the computation of non linear indices can contribute to enhancing the diagnostic power and reliability of fetal monitoring. The paper shows how advanced signal processing approaches can contribute to developing new diagnostic and classification indices. Their usefulness is evaluated by comparing two selected populations: normal fetuses and intra uterine growth restricted (IUGR) fetuses. Results show that the computation of different indices on FHRV signals, either linear and nonlinear, gives helpful indications to describe pathophysiological mechanisms involved in the cardiovascular and neural system controlling the fetal heart. As a further contribution, the paper briefly describes how the introduction of wearable systems for fetal ECG recording could provide new technological solutions improving the quality and usability of prenatal monitoring. © 2014 Maria G. Signorini et al
The "safe falls, safe schools" multicentre international project: Evaluation and analysis of backwards falling ability in Italian secondary schools
Problem statement: Different studies have reported on the epidemiology related to injuries resulting from falls, which are the most common causes of injury in Italy. The World Health Organization considers falls as the second leading cause of accidental or unintentional deaths worldwide. However, it has been demonstrated that the Safe Fall, Safe Schools Programme (SFSSP) based on 10-min warm-up sessions is able to teach techniques for falling backwards in safe way during physical education (PE) classes. Unfortunately, there are no studies that have analysed extensive warm-up and detraining effects related to the age. Aim: The aim of this study was to assess extensive specific warm-up (20 min) and detraining effects after five weeks on the SFSSP on Italian secondary school students according to age. Methods: Eighty-seven secondary school students took part in this investigation. Students were divided into two groups, equally distributed by age. The trial-control group (TC=39) and the control-trial group (CT=48) performed the same PE lesson for 10 weeks. In the first five weeks, two different 20-min warm-up exercises were performed (TC=SFSSP; CT=conventional warm-up); after five weeks, the warm-ups were inverted (TC=conventional warm-up; CT=SFSSP). The backwards falling ability test carried out among both groups was evaluated in relation to the position of the neck, trunk, knees, hips and hands, before and after five and 10 weeks. Results: McNemar\u2019s test showed significant differences (between pre-and mid-time points, P<0.05) for the neck, trunk, hip and hands, while no significant differences were found in the knee value (P=0.581 in TC). No differences were found between the mid-and post-time points for TC. In CT, no differences were found in-between (pre-and mid-time points, P>0.05) for all variables studied. Significant differences (P<0.05) were found in-between the mid-and post- time points for CT in all variables studied. Analysis of the total scores for SFSSP showed significantly differences in TC and CT (P<0.0001). The Wilcoxon signed-rank test showed no significant differences (total scores: first year=1.68\ub11.05 AU; fifth year=1.47\ub10.86 AU; P=0.34) before the SFSSP intervention, while the SFSSP was able to improve the ability after intervention (total scores: first year=4.47\ub10.84 AU; fifth year=3.91\ub11.40 AU; P<0.01). Conclusions: The SFSSP was able to improve motor ability for both groups and the detraining effect was found to maintain the same ability level compared to that after the SFSSP intervention. Participants started with the same level of backwards falling ability and each group, after the intervention, significantly raised its score, confirming the efficacy of the intervention. Therefore, the SFSSP could be included in the standard national programme without changing the standard training lesson
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