311 research outputs found

    Modern Geometry

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    Tests of monolithic active pixel sensors at national synchrotron light source

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    The paper discusses basic characterization of Monolithic Active Pixel Sensors (MAPS) carried out at the X12A beam-line at National Synchrotron Light Source (NSLS), Upton, NY, USA. The tested device was a MIMOSA V (MV) chip, back-thinned down to the epitaxial layer. This 1M pixels device features a pixel size of 17X17µm^2 and was designed in a 0,6µm CMOS process. The X-ray beam energies used range from 5 to 12 keV. Examples of direct X-ray imaging capabilities are presented

    Enhanced frequency up-conversion in Rb vapor

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    We demonstrate highly efficient generation of coherent 420nm light via up-conversion of near-infrared lasers in a hot rubidium vapor cell. By optimizing pump polarizations and frequencies we achieve a single-pass conversion efficiency of 260% per Watt, significantly higher than in previous experiments. A full exploration of the coherent light generation and fluorescence as a function of both pump frequencies reveals that coherent blue light is generated close to 85Rb two-photon resonances, as predicted by theory, but at high vapor pressure is suppressed in spectral regions that do not support phase matching or exhibit single-photon Kerr refraction. Favorable scaling of our current 1mW blue beam power with additional pump power is predicted.Comment: 6 pages, 4 figures. Modified to include referees' improvement

    Spatiotemporal Response of Crystals in X-ray Bragg Diffraction

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    The spatiotemporal response of crystals in x-ray Bragg diffraction resulting from excitation by an ultra-short, laterally confined x-ray pulse is studied theoretically. The theory presents an extension of the analysis in symmetric reflection geometry [1] to the generic case, which includes Bragg diffraction both in reflection (Bragg) and transmission (Laue) asymmetric scattering geometries. The spatiotemporal response is presented as a product of a crystal-intrinsic plane wave spatiotemporal response function and an envelope function defined by the crystal-independent transverse profile of the incident beam and the scattering geometry. The diffracted wavefields exhibit amplitude modulation perpendicular to the propagation direction due to both angular dispersion and the dispersion due to Bragg's law. The characteristic measure of the spatiotemporal response is expressed in terms of a few parameters: the extinction length, crystal thickness, Bragg angle, asymmetry angle, and the speed of light. Applications to self-seeding of hard x-ray free electron lasers are discussed, with particular emphasis on the relative advantages of using either the Bragg or Laue scattering geometries. Intensity front inclination in asymmetric diffraction can be used to make snapshots of ultra-fast processes with femtosecond resolution

    Warmer temperatures reduce the vectorial capacity of malaria mosquitoes

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    The development rate of parasites and pathogens within vectors typically increases with temperature. Accordingly, transmission intensity is generally assumed to be higher under warmer conditions. However, development is only one component of parasite/pathogen life history and there has been little research exploring the temperature sensitivity of other traits that contribute to transmission intensity. Here, using a rodent malaria, we show that vector competence (the maximum proportion of infectious mosquitoes, which implicitly includes parasite survival across the incubation period) tails off at higher temperatures, even though parasite development rate increases. We also show that the standard measure of the parasite incubation period (i.e. time until the first mosquitoes within a cohort become infectious following an infected blood-meal) is incomplete because parasite development follows a cumulative distribution, which itself varies with temperature. Including these effects in a simple model dramatically alters estimates of transmission intensity and reduces the optimum temperature for transmission. These results highlight the need to understand the interactive effects of environmental temperature on multiple host-disease life-history traits and challenge the assumptions of many current disease models that ignore this complexity
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