Eigenvalue problems for fractional differential equations with mixed derivatives and generalized p-Laplacian

This paper reports the investigation of eigenvalue problems for two classes of nonlinear fractional differential equations with generalized p-Laplacian operator involving both Riemann–Liouville fractional derivatives and Caputo fractional derivatives. By means of fixed point theorem on cones, some sufficient conditions are derived for the existence, multiplicity and nonexistence of positive solutions to the boundary value problems. Finally, an example is presented to further verify the correctness of the main theoretical results and illustrate the wide range of their potential applications

A Novel Four-Wing Hyperchaotic Complex System and Its Complex Modified Hybrid Projective Synchronization with Different Dimensions

We introduce a new Dadras system with complex variables which can exhibit both four-wing hyperchaotic and chaotic attractors. Some dynamic properties of the system have been described including Lyapunov exponents, fractal dimensions, and Poincaré maps. More importantly, we focus on a new type of synchronization method of modified hybrid project synchronization with complex transformation matrix (CMHPS) for different dimensional hyperchaotic and chaotic complex systems with complex parameters, where the drive and response systems can be asymptotically synchronized up to a desired complex transformation matrix, not a diagonal matrix. Furthermore, CMHPS between the novel hyperchaotic Dadras complex system and other two different dimensional complex chaotic systems is provided as an example to discuss increased order synchronization and reduced order synchronization, respectively. Numerical results verify the feasibility and effectiveness of the presented schemes

Changes in bacterial community of soil induced by long-term straw returning

Straw returning is an effective way to improve soil quality. Whether the bacterial community development has been changed by long-term straw returning in non-calcareous soil is not clear. In this study, the following five treatments were administered: soil without fertilizer (CK); wheat and corn straw returning (WC); wheat straw returning with 276 kg N ha−1 yr−1 (WN); manure, 60,000 kg ha−1 pig manure compost (M) and wheat and corn straw returning with 276 kg N ha−1 yr−1 (WCN). The high-throughput 16S rRNA sequencing technology was used to evaluate the bacterial communities. The results showed that the community was composed mostly of two dominant groups (Proteobacteria and Acidobacteria). Bacterial diversity increased after the application of straw and manure. Principal component analyses revealed that the soil bacterial community differed significantly between treatments. The WCN treatment showed relatively higher total soil N, available P, available K, and organic carbon and invertase, urease, cellulase activities and yield than the WC treatment. Our results suggested that application of N fertilizer to straw returning soil had significantly higher soil fertility and enzyme activity than straw returning alone, which resulted in a different bacterial community composition, Stenotrophomonas, Pseudoxanthomonas, and Acinetobacter which were the dominant genera in the WC treatment while Candidatus, Koribacter and Granulicella were the dominant genera in the WCN treatment. To summarize, wheat and maize straw returning with N fertilizer would be the optimum proposal for improving soil quality and yield in the future in non-calcareous fluro-acquic-wheat and maize cultivated soils in the North China Plain in China

Influence of acrylamide on ROS, Hsp27 and NF-kB in bone marrow mesenchymal stem cells

The bone marrow mesenchymal stem cells (BM-MSCs) treated with acrylamide (ACR) were used to make out the immune response to ROS, interleukin-8 and phosphorylated Hsp27 of ACR. ACR was reported as a probable human carcinogen, neurotoxic and mutagenic. BMMSCs have the capability of immunoregulation, and participate in the process of multiple immune response. It has attracted the attention of researchers that these cells have priority to move to the damaged tissue, as a kind of potential therapeutic tool for tissue repair. ACR and BMMSCs are related to immune reactions, especially those involving in tumours and cancers. However, the interaction between ACR and BMMSCs is still poorly understood. In present study, we report the influence of ACR on BMMSCs. At first, BMMSCs were disposed with 0.5mM ACR for 72 h, and then the secretion of ROS, interleukin-8, phospho- Hsp27 and NF-kB activities, apoptosis and cell cycle, respectively, were determined. The results showed that the secretion of ROS, interleukin-8 and phosph-Hsp27 increased and NF-kB was activated, while the apoptosis and cell cycle have no obvious alteration. In conclusion, ACR probably activated the NF-kB pathway in BMMSCs via oxidative stress, which may provide new insights to study the immune response and the influence mechanism of ACR

Non-steroidal anti-inflammatory drugs target TWISTED DWARF1-regulated actin dynamics and auxin transport-mediated plant development

The widely used non-steroidal anti-inflammatory drugs (NSAIDs) are derivatives of the phytohormone salicylic acid (SA). SA is well known to regulate plant immunity and development, whereas there have been few reports focusing on the effects of NSAIDs in plants. Our studies here reveal that NSAIDs exhibit largely overlapping physiological activities to SA in the model plant Arabidopsis. NSAID treatments lead to shorter and agravitropic primary roots and inhibited lateral root organogenesis. Notably, in addition to the SA-like action, which in roots involves binding to the protein phosphatase 2A (PP2A), NSAIDs also exhibit PP2A-independent effects. Cell biological and biochemical analyses reveal that many NSAIDs bind directly to and inhibit the chaperone activity of TWISTED DWARF1, thereby regulating actin cytoskeleton dynamics and subsequent endosomal trafficking. Our findings uncover an unexpected bioactivity of human pharmaceuticals in plants and provide insights into the molecular mechanism underlying the cellular action of this class of anti-inflammatory compounds

Adding power of artificial intelligence to situational awareness of large interconnections dominated by inverter‐based resources

Large-scale power systems exhibit more complex dynamics due to the increasing integration of inverter-based resources (IBRs). Therefore, there is an urgent need to enhance the situational awareness capability for better monitoring and control of power grids dominated by IBRs. As a pioneering Wide-Area Measurement System, FNET/GridEye has developed and implemented various advanced applications based on the collected synchrophasor measurements to enhance the situational awareness capability of large-scale power grids. This study provides an overview of the latest progress of FNET/GridEye. The sensors, communication, and data servers are upgraded to handle ultra-high density synchrophasor and point-on-wave data to monitor system dynamics with more details. More importantly, several artificial intelligence (AI)-based advanced applications are introduced, including AI-based inertia estimation, AI-based disturbance size and location estimation, AI-based system stability assessment, and AI-based data authentication