Cultural and Creative Industries and Art Education

AbstractThe progress of cultural and creative industries calls for numerous talents in this field. After an analysis of the development of cultural and creative industries, this paper demonstrates that art education is the most vital approaches of all to cultivate cultural and creative talents, and that it offers intellectual support and talents for the development of cultural and creative industries, which in return facilitates the development of art education. On this basis, the thesis probes into the mode of development of art education with the rise of cultural and creative industries so as to offer new ideas for college art education

(2E,6E)-2,6-Bis(4-ethoxy­benzyl­idene)cyclo­hexa­none

The title compound, C24H26O3, was prepared by the condensation reaction of 4-ethoxy­benzaldehyde with cyclo­hexa­none. The mol­ecule has crystallographic mirror symmetry and exhibits a butterfly-shaped geometry, with a dihedral angle of 5.46 (1)° between the two benzene rings. Weak inter­molecular C—H⋯π inter­actions help stabilize the crystal structure

Existence of Positive Solution for BVP of Nonlinear Fractional Differential Equation

We consider the following boundary value problem of nonlinear fractional differential equation: (CD0+αu)(t)=f(t,u(t)),  t∈[0,1],  u(0)=0,   u′(0)+u′′(0)=0,  u′(1)+u′′(1)=0, where α∈(2,3] is a real number,  CD0+α denotes the standard Caputo fractional derivative, and f:[0,1]×[0,+∞)→[0,+∞) is continuous. By using the well-known Guo-Krasnoselskii fixed point theorem, we obtain the existence of at least one positive solution for the above problem

Coverage Analysis for Cellular-Connected Random 3D Mobile UAVs with Directional Antennas

This letter proposes an analytical framework to evaluate the coverage performance of a cellular-connected unmanned aerial vehicle (UAV) network in which UAV user equipments (UAV-UEs) are equipped with directional antennas and move according to a three-dimensional (3D) mobility model. The ground base stations (GBSs) equipped with practical down-tilted antennas are distributed according to a Poisson point process (PPP). With tools from stochastic geometry, we derive the handover probability and coverage probability of a random UAV-UE under the strongest average received signal strength (RSS) association strategy. The proposed analytical framework allows to investigate the effect of UAV-UE antenna beamwidth, mobility speed, cell association, and vertical motions on both the handover probability and coverage probability. We conclude that the optimal UAV-UE antenna beamwidth decreases with the GBS density, and the omnidirectional antenna model is preferred in the sparse network scenario. What's more, the superiority of the strongest average RSS association over the nearest association diminishes with the increment of GBS density.Comment: 5 pages, 5 figures, submitted to IEEE Wireless Communications Letter

Genome-Wide Identification of Papain-Like Cysteine Proteases in Gossypium hirsutum and Functional Characterization in Response to Verticillium dahliae

Cotton, a natural fiber producing crop of huge importance, is often prone to attack of Verticillium dahliae. Papain-like cysteine proteases (PLCPs) constitute a large family in plants and were proposed to involve in plant defense against pathogen attack in a number of studies. However, there is no detailed characterization of PLCP genes in cotton against infection of V. dahliae. In this study, we carried out a genome-wide analysis in cotton and identified seventy-eight PLCPs, which were divided into nine subfamilies based on their evolution phylogeny: RD21 (responsive to desiccation 21), CEP (cysteine endopeptidase), XCP (xylem cysteine peptidase), XBCP3 (xylem bark cysteine peptidase 3), THI, SAG12 (senescence-associated gene 12), RD19 (responsive to desiccation 19), ALP (aleurain-like protease) and CTB (cathepsin B-like). Genes in each subfamily exhibit a similar structure and motif composition. The expression patterns of these genes in different organs were examined, and subfamily RD21 was the most abundant in these families. Expression profiles under abiotic stress showed that thirty-five PLCP genes were induced by multiple stresses. Further transcriptome analysis showed that sixteen PLCP genes were up-regulated in response to V. dahliae in cotton. Among those, GhRD21-7 showed a higher transcription level than most other PLCP genes. Additionally, over-expression of GhRD21-7 led to enhanced resistance and RNAi lines were more susceptible to V. dahliae in cotton. Our results provide valuable information for future functional genomic studies of PLCP gene family in cotton

Patterns of adverse childhood experiences and suicidal behaviors in adolescents: A four-province study in China

This is an accepted manuscript of a paper published by Elsevier on 23/02/2021, available online at: https://doi.org/10.1016/j.jad.2021.02.045 The accepted manuscript of the publication may differ from the final published version.Background:: Adverse childhood experiences (ACEs) are associated with increased suicidal behaviors in adolescents and most research has been restricted to certain types of or cumulative exposure to ACEs. Few studies have examined the association between patterns of ACEs and suicidal behaviors. Objective:: To identify the contributions of type and pattern of exposure to ACEs to suicidal behaviors and their gender differences among middle school students in China. Methods:: A school-based health survey was conducted in four provinces in China between 2017 and 2018. 14 500 students aged 10–20 years completed standard questionnaires, to record details of ACEs, suicide ideation, suicide plan, and suicide attempt. Results:: Latent class analysis indicated four distinct patterns of ACEs exposure: high ACEs (6.3%), high abuse and neglect (21.4%), high neglect (45.5%), and low ACEs (26.8%). Logistic analyses showed that, compared with low ACEs, the high ACEs were more likely to report suicidal behaviors. No gender differences were found in the independent effects of ACEs type or pattern on suicidal behaviors, except for the emotional neglect associated with suicidal behaviors in girls than boys. Limitations:: The study was cross-sectional and used self-reported questionnaires. Thus, it is difficult to establish a causal relationship between patterns of ACEs and suicidal behaviors. Conclusion:: Our findings addressed the need for a comprehensive consideration of ACEs in preventive healthcare work to identify children exposed to the most problematic ACE patterns. The study provided the evidence of targeted intervention to preempt the emergence of suicide behavior in at-risk students in adolescents.Funding for the project was provided by National Natural Science Foundation of China (82073576 & 81773453).Published versio

Production, characterization, and epitope mapping of a monoclonal antibody against genotype VII Newcastle disease virus V protein

Newcastle disease virus (NDV) V protein is crucial for viral interferon (IFN) antagonism and virulence, determining its host range restriction. However, little information is available on the B cell epitopes of V protein and the subcellular movement of V protein in the process of NDV infection. In this study, the monoclonal antibody (mAb) clone 3D7 against genotype VII NDV V protein was generated by immunizing mice with a purified recombinant His-tagged carboxyl-terminal domain (CTD) region of V protein. Fine epitope mapping analysis and B-cell epitope prediction indicated that mAb 3D7 recognized a linear epitope 152RGPAELWK159, which is located in the V protein CTD region. Sequence alignment showed that the mAb clone 3D7-recognized epitope is highly conserved among Class II genotype VII NDV strains, but not among other genotypes, suggesting it could serve as a genetic marker to differentiate NDV genotypes. Furthermore, the movement of V protein during NDV replication in infected cells were determined by using this mAb. It was found that V protein localized around the nucleus during virus replication. The establishment of V protein-specific mAb and identification of its epitope extend our understanding of the antigenic characteristics of V protein and provide a basis for the development of epitope-based diagnostic assays