Revisiting Copenhagen climate mitigation targets

Many economies set climate mitigation targets for 2020 at the 2009 15th Conference of the Parties conference of the United Nations Framework Convention on Climate Change in Copenhagen. Yet no retrospective review of the implementation and actual mitigation associated with these targets has materialized. Here we track the national CO2 emissions from both territory and consumption (trade adjusted) perspectives to assess socioeconomic factors affecting changes in emissions. Among the 34 countries analysed, 12 failed to meet their targets (among them Portugal, Spain and Japan) and 7 achieved the target for territorial emissions, albeit with carbon leakage through international trade to meet domestic demand while increasing emissions in other countries. Key factors in meeting targets were intensity reduction of energy and the improvement of the energy mix. However, many countries efforts fell short of their latest nationally determined contributions. Timely tracking and review of mitigation efforts are critical for meeting the Paris Agreement targets

Simultaneous Monitoring of Multiple People's Vital Sign Leveraging a Single Phased-MIMO Radar

Vital sign monitoring plays a critical role in tracking the physiological state of people and enabling various health-related applications (e.g., recommending a change of lifestyle, examining the risk of diseases). Traditional approaches rely on hospitalization or body-attached instruments, which are costly and intrusive. Therefore, researchers have been exploring contact-less vital sign monitoring with radio frequency signals in recent years. Early studies with continuous wave radars/WiFi devices work on detecting vital signs of a single individual, but it still remains challenging to simultaneously monitor vital signs of multiple subjects, especially those who locate in proximity. In this paper, we design and implement a time-division multiplexing (TDM) phased-MIMO radar sensing scheme for high-precision vital sign monitoring of multiple people. Our phased-MIMO radar can steer the mmWave beam towards different directions with a micro-second delay, which enables capturing the vital signs of multiple individuals at the same radial distance to the radar. Furthermore, we develop a TDM-MIMO technique to fully utilize all transmitting antenna (TX)-receiving antenna (RX) pairs, thereby significantly boosting the signal-to-noise ratio. Based on the designed TDM phased-MIMO radar, we develop a system to automatically localize multiple human subjects and estimate their vital signs. Extensive evaluations show that under two-subject scenarios, our system can achieve an error of less than 1 beat per minute (BPM) and 3 BPM for breathing rate (BR) and heartbeat rate (HR) estimations, respectively, at a subject-to-radar distance of $1.6~m$. The minimal subject-to-subject angle separation is $40{\deg}$, corresponding to a close distance of $0.5~m$ between two subjects, which outperforms the state-of-the-art

Harpin-induced expression and transgenic overexpression of the phloem protein gene AtPP2-A1 in Arabidopsis repress phloem feeding of the green peach aphid Myzus persicae

<p>Abstract</p> <p>Background</p> <p>Treatment of plants with HrpN_Ea, a protein of harpin group produced by Gram-negative plant pathogenic bacteria, induces plant resistance to insect herbivores, including the green peach aphid <it>Myzus persicae</it>, a generalist phloem-feeding insect. Under attacks by phloem-feeding insects, plants defend themselves using the phloem-based defense mechanism, which is supposed to involve the phloem protein 2 (PP2), one of the most abundant proteins in the phloem sap. The purpose of this study was to obtain genetic evidence for the function of the <it>Arabidopsis thaliana </it>(Arabidopsis) PP2-encoding gene <it>AtPP2-A1 </it>in resistance to <it>M. persicae </it>when the plant was treated with HrpN_Eaand after the plant was transformed with <it>AtPP2-A1</it>.</p> <p>Results</p> <p>The electrical penetration graph technique was used to visualize the phloem-feeding activities of apterous agamic <it>M. persicae </it>females on leaves of Arabidopsis plants treated with HrpN_Eaand an inactive protein control, respectively. A repression of phloem feeding was induced by HrpN_Eain wild-type (WT) Arabidopsis but not in <it>atpp2-a1</it>/E/142, the plant mutant that had a defect in the <it>AtPP2-A1 </it>gene, the most HrpN_Ea-responsive of 30 <it>AtPP2 </it>genes. In WT rather than <it>atpp2-a1</it>/E/142, the deterrent effect of HrpN_Eatreatment on the phloem-feeding activity accompanied an enhancement of <it>AtPP2-A1 </it>expression. In PP2OETAt (<it>AtPP2-A1</it>-overexpression transgenic <it>Arabidopsis thaliana</it>) plants, abundant amounts of the <it>AtPP2-A1 </it>gene transcript were detected in different organs, including leaves, stems, calyces, and petals. All these organs had a deterrent effect on the phloem-feeding activity compared with the same organs of the transgenic control plant. When a large-scale aphid population was monitored for 24 hours, there was a significant decrease in the number of aphids that colonized leaves of HrpN_Ea-treated WT and PP2OETAt plants, respectively, compared with control plants.</p> <p>Conclusions</p> <p>The repression in phloem-feeding activities of <it>M. persicae </it>as a result of <it>AtPP2-A1 </it>overexpression, and as a deterrent effect of HrpN_Eatreatment in WT Arabidopsis rather than the <it>atpp2-a1</it>/E/142 mutant suggest that <it>AtPP2-A1 </it>plays a role in plant resistance to the insect, particularly at the phloem-feeding stage. The accompanied change of aphid population in leaf colonies suggests that the function of <it>AtPP2-A1 </it>is related to colonization of the plant.</p

Hydrothermal catalytic production of fuels and chemicals from aquatic biomass

One of the promising avenues for biomass processing is the use of water as a reaction medium for wet or aquatic biomass. This review focuses on the hydrothermal catalytic production of fuels and chemicals from aquatic biomass. Two different regimes for conversion of aquatic biomass in hydrothermal conditions are discussed in detail. The first is hydrothermal liquefaction, and the second is hydrothermal gasification. The goals of these processes are to produce liquid‐fuel‐range hydrocarbons and methane or hydrogen, respectively. The catalytic upgrading of biocrude resulting from noncatalytic liquefaction and the stability and degradation of catalysts in high temperature water are also discussed. The review concludes with a brief discussion of the outlook for and opportunities within the field of hydrothermal catalytic valorization of biomass. Copyright © 2012 Society of Chemical IndustryPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94889/1/jctb3933.pd

CdSe Quantum Dot (QD)-Induced Morphological and Functional Impairments to Liver in Mice

Quantum dots (QDs), as unique nanoparticle probes, have been used in in vivo fluorescence imaging such as cancers. Due to the novel characteristics in fluorescence, QDs represent a family of promising substances to be used in experimental and clinical imaging. Thus far, the toxicity and harmful health effects from exposure (including environmental exposure) to QDs are not recognized, but are largely concerned by the public. To assess the biological effects of QDs, we established a mouse model of acute and chronic exposure to QDs. Results from the present study suggested that QD particles could readily spread into various organs, and liver was the major organ for QD accumulation in mice from both the acute and chronic exposure. QDs caused significant impairments to livers from mice with both acute and chronic QD exposure as reflected by morphological alternation to the hepatic lobules and increased oxidative stress. Moreover, QDs remarkably induced the production of intracellular reactive oxygen species (ROS) along with cytotoxicity, as characterized by a significant increase of the malondialdehyde (MDA) level within hepatocytes. However, the increase of the MDA level in response to QD treatment could be partially blunted by the pre-treatment of cells with beta-mercaptoethanol (β-ME). These data suggested ROS played a crucial role in causing oxidative stress-associated cellular damage from QD exposure; nevertheless other unidentified mediators might also be involved in QD-mediated cellular impairments. Importantly, we demonstrated that the hepatoxicity caused by QDs in vivo and in vitro was much greater than that induced by cadmium ions at a similar or even a higher dose. Taken together, the mechanism underlying QD-mediated biological influences might derive from the toxicity of QD particles themselves, and from free cadmium ions liberated from QDs as well

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Application of Linear Regression Mathematical Model in the Evaluation of Teachers’ Informatization Quality

With the widespread application of information technology and the continuous deepening of my country’s education informatization construction, the educational field has increasingly higher requirements for teachers’ informatization quality. The advancement of the process of education informatization depends to a large extent on the level of teachers’ own level of informatization and has gradually become an important indicator to measure the informatization of education. The main body of education and the decisive factor are teachers. The scientific and reasonable evaluation of informatization education is an important content of today’s education informatization. This paper uses regression analysis to evaluate the teacher education information system and uses mathematical statistics to establish a linear regression model for the city and analyze and calculate it. Through the quantitative analysis of the evaluation index system of the education informatization level, the multiple linear regression analysis method was used to establish the linear regression mathematical model of the school education informatization level on each secondary index, and the influence of various indicators on the school education informatization level was analyzed to establish a scientific evaluation system to evaluate the literacy of teachers’ informatization education and to give suggestions for improving the level of school education informatization. The design of the evaluation system is more scientific and reasonable, the regression error is small, the results obtained are more accurate, and the impact of nonlinear errors is basically eliminated

A new K nearest neighbours algorithm using cell grids for 3D scattered point cloud

In this paper, we propose one novel and efficient K nearest neighbours search algorithm based on 3D uniform cell grids. First, a simple min-max box is used to store all the points and a twice division strategy is adopted to determine the edge length of basic grids. Then we limit the search space for each grid with certain query points to control the amount of distance calculations under a suitable level. And the computational cost of sorting operations is reduced effectively through avoiding the unnecessary calculations, with the help of properly determined subspaces and sphere spaces for points. Compared with existing related algorithms, our method can search for the K nearest neighbours accurately and quickly, and it has many possible applications in the fields using 3D scattered point clouds.close0