50 research outputs found
Crab cavities for linear colliders
Crab cavities have been proposed for a wide number of accelerators and
interest in crab cavities has recently increased after the successful operation
of a pair of crab cavities in KEK-B. In particular crab cavities are required
for both the ILC and CLIC linear colliders for bunch alignment. Consideration
of bunch structure and size constraints favour a 3.9 GHz superconducting,
multi-cell cavity as the solution for ILC, whilst bunch structure and
beam-loading considerations suggest an X-band copper travelling wave structure
for CLIC. These two cavity solutions are very different in design but share
complex design issues. Phase stabilisation, beam loading, wakefields and mode
damping are fundamental issues for these crab cavities. Requirements and
potential design solutions will be discussed for both colliders.Comment: 3 pages. To be published in proceedings of LINAC 2008, Victoria,
Canad
Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus
The goal of this study is to clarify whether the expression of metallothionein (MT) could affect the prognosis and the metastatic potential of squamous cell carcinoma (SCC) of the oesophagus. In paraffin-embedded specimens resected from 57 patients, MT mRNA and protein expressions were detected by in situ hybridization and immunohistochemistry respectively. The expression of MT was evaluated in respect of clinicopathologic variables and patients' survival. MT mRNA expression was significantly associated with the proportion of lymph node metastasis (71% in MT mRNA-positive tumours vs 42% in MT mRNA-negative tumours; P = 0.0343) and that of distant metastasis (29% in MT mRNA-positive tumours vs 5% in MT mRNA-negative tumours; P = 0.0452). In respect of MT protein expression, the frequency of distant metastasis was more common in MT-positive tumours than in MT-negative tumours (30% in MT-positive tumours vs 8% in MT-negative tumours; P = 0.0446). The survival rate of the patients with MT protein-negative tumours was significantly better than that of the patients with MT protein-positive tumours (P = 0.0340). There was a positive correlation between the expression of MT protein and that of proliferating cell nuclear antigen (P = 0.0018). Therefore, we conclude that MT expression, both at the mRNA and protein levels, may be a potential marker predicting metastatic and proliferative activities of oesophageal SCC. © 1999 Cancer Research Campaig
La malattia da Accumulo degli Esteri di Colesterolo (CESD) è una malattia sottodiagnosticata
13th annual seed catalogue 1912 : poultry and stock supplies, seeds, fertilizers, garden implements, and insect-destroyers /
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Effect of clinical mastitis on the lactation curve: a mixed model estimationusing daily milk weights
The objective of this study was to estimate the milk production losses associated with clinical mastitis using mixed linear models and correlation structures that have not been available previously. Data used included computer-recorded daily milk yields and detailed and accurate recordings of clinical mastitis cases. Two commercial Holstein dairy farms in New York State participated in the study, one with 650 lactating cows and another that began the study with 830 lactating cows and increased to 1120 cows by the end of the study. Cows on both farms were housed in free stall barns and milked 3 times daily in milking parlors. Electrical conductivity was used as a diagnostic aid for clinical mastitis on both farms. Date of clinical onset was recorded for every episode of clinical mastitis as well as for 8 other diseases defined using standardized case definitions (dystocia, milk fever, retained placenta, metritis, ketosis, displaced abomasum, lameness, and cystic ovarian disease) during the study period of October 1, 1999 to July 31, 2001. The mixed linear model for explaining variation in the outcome variable daily milk yield relative to non-mastitic herdmates found the terms for all 9 diseases studied, including clinical mastitis, significant. The model with an autoregressive correlation structure was preferred based on −2 * log likelihood, Akaike\u27s information criterion, and Bayesian information criterion as well as savings in degrees of freedom. Separate analyses were run for first lactation cows and for second-plus lactation cows because their lactation curves were shaped differently. Adjusting for the effects of the other 8 diseases, milk production loss from clinical mastitis during the whole lactation was estimated as approximately 598 kg for second-plus lactation cows. However, cows that contracted mastitis had a daily production advantage of 2.6 kg over their herdmates until they contracted the disease. When compared with this potentially higher milk production, the total loss from clinical mastitis was estimated as 1181 kg
A missense mutation (Thr-6Pro) in the lysosomal acid lipase (LAL) gene is present with a high frequency in three different ethnic populations: impact on serum lipoprotein concentrations
Real-time monitoring of electro-mechanical effect in carbon-fiber reinforced polymer using HTS SQUID
Stress damage of cross-ply or quasi-isotropic carbon-fiber reinforced
polymer laminates, commonly used in aerospace structures, has been monitored
in real-time during quasi-static loading. The fiber displacement in the
matrix due to mechanical loading have been detected using atomic force
microscopy techniques. A correlation between mechanical and electrical
effects in the material has been confirmed by electrical and magnetic
measurement using an eddy current technique based on high critical
temperature dc Superconducting Quantum Interference Device magnetometer