William Morris and Diego Rivera: The Pursuit of Art for the People

The purpose of this thesis is to draw parallels between the art and philosophy of William Morris (1834-1896) and Diego Rivera (1886-1957). Morris drew on his interest in gothic art and architecture, his love of Romantic literature, and his commitment to social reform, to articulate the aesthetic and social vision of the Arts and Crafts Movement in England. Examples of Morris’s writings and his handicraft in the form of wallpapers, books, furniture, and the Red House will be examined. Diego Rivera was a Mexican painter and socialist activist perhaps best known for his murals depicting the working class. Several of Rivera’s murals will be discussed. Although not contemporaries, Morris and Rivera shared ideological kinship by expressing national identity in their work, advocating for art for all people, and promoting a socialist agenda through their writing and art. Divided into two sections, the paper provides a brief biography of each man, describing their lives and works, followed by a discussion of the nationalistic themes portrayed in their work, their views on availability of art for everyone, and their beliefs that socialism could elevate working classes. William Morris and Diego Rivera lived on different continents during separate time periods in history and yet had similar sources of inspiration that influenced their work. Both were influenced by architecture, the relationship between labor and mechanized production, the cultural and historical identity of their respective homelands, and socialist politics; both, in their own way, embraced their theme of art for the people

The Two Worlds of University Publishing

24 p. 23 cm. "Given on November 16, 1967, under the joint sponsorship of the University of Kansas Libraries and of the University Press of Kansas, on the occasion of the founding of the new press." Bibliography: p. 24

Sustainable management of Central Victorian mineral waters

Central Victoria contains more than 100 carbonated mineral water springs, many were discovered when uncovered by alluvial gold mining activities of the 1850's. The mineral springs are located at distances of 2 to 45 km from the crest of the Great Dividing Range, and are situated at elevations from 700 down to 200 m above sea level. The discharge from individual springs is small, and usually falls in the range 0.01 0.4 L/s (0.3-13 ML/annum). The mineral spring waters are cold ranging from around 10o C at the higher elevations to 17o C at the springs occurring at lower elevations. The carbonated mineral waters are a facies of the more widely distributed high bicarbonate alkalinity groundwater in the deep circulation systems of Central Victoria. The carbonated mineral waters are mildly acidic (pH 5.7 - 6.3), oxidic (Eh +50 to +100 mv), have low chloride (median 60 mg/L), high bicarbonate (median 1500 mg/L) and low sulphate (median 18 mg/L) concentrations. The water becomes slightly effervescent on discharge from the springs, and may be vigorously gassy when escaping from bores in the ascension zone. The characteristics of the mineral water chemistry may be explained by clay reactions - proton exchange, carbonate dissolution and base exchange. In the ascension zone heterogeneous thermodynamics, including the dissociation characteristics of a diprotic acid, acidity regulation by non carbonate equilibria, in particular by iron chemistry results in effervescence as pressure, degassing, acidity change and electro neutrality determine the water chemistry. Local characterisation of the m ineral waters arises from a superimposition of flux and mixing relationships encountered in discharge or ascension zones on regional trends. In Central Victoria the bedrock aquifer consists of interbedded lithic and arkosic grits, sandstones and graphitic shales. The most common occurrence is in rocks of Lower Ordovician age, but mineral waters also occur in Cambrian, Upper Silurian and Lower Devonian strata. The rocks have been subjected to variable but low grade regional metamorphism. Sandstone and grit units may retain some primary porosity, and thin intersections of unconsolidated sediment occur in bore holes. Narrow bands of saccharoidal marble and cone-in-cone limestone are present, but carbonates are a minor constituent of the rock mass (0.5% - 2%) and associated diagenetic ankerite. Organic carbon may exceed 5% in the black graphitic shales. Deep weathering profiles are developed on these rocks with elution of carbonates and kaolinisation silicate minerals. The rocks are folded asymmetrically and cut by strongly developed concordant meridional bearing thrust faults. The linear character of the rock mass failure produces anisotropy and heterogeneity. Deep fissure flow systems emanating from the Great Dividing Range follow litho structural corridors for distances of more than 40 km and groundwater has been observed in the bedrock mines of Central Victoria at depths of more than 1.6 km. The sustainable management of the mineral water resource involves the maintenance of yield, water quality and public equity. Sustaining Public Equity was initiated in 1865 by the formal establishment of mineral spring reserves. Reserves were proclaimed to preserve the springs from "the ravages of mining, and for public recreation and amusement". At Hepburn the first Pavilion was erected in 1869; a bottling plant in 1880 and a bath house was built in 1890. The region is the centre of balneology and hydrotherapy in Victoria and provides a 150 year history of development, conflict and sustainable resource management resolution. The spring reserves and surrounding buffer areas in the planning schemes offer protection for the discharge zones, but there is increasing tendency to commercialise and encroach on the reserves and allocate the mineral water for commercial or semi commercial development. Past evidence illustrates that management of the water quality, its salinity and gas content, is equally difficu lt as the maintenance of the flow of the springs and the continuation of public equity. Long term sustainable management is an evolving process that recognises past failures and crises. It shares the failure profile exhibited in many examples of overseas development of mineral and thermal waters. Legal Principles and endeavours outside the jurisdiction of the water and environment protection sectors are pre-eminent in the decision making processes. Nevertheless, the existing regulatory processes do have the potential to protect the resource

Catheter-associated meatal pressure injuries (CAMPI) in patients with long-term urethral catheters—a cross-sectional study of 200 patients

Background: Indwelling urethral catheters (IDC) are ubiquitous to healthcare settings, and are associated with many familiar risks like haematuria, infections, bladder spasms and stones. However, a less known complication is catheter-associated meatal pressure injury (CAMPI), especially in those with long-term IDCs. The objective of this study was to explore the prevalence, associated features and management of CAMPI in adults with a long-term IDC. Methods: A cross-sectional multi-centre study was undertaken of 200 adults with a long-term IDC across regional south-west Queensland, Australia between June 2019 to June 2021. The prevalence of CAMPI was determined by clinical examination, voluntary surveys completed by participants and documentation in medical records. Key IDC statistics included total duration of IDC, location of IDC changes, IDC size, type and fixation. Results: Out of 200 adults with a long-term IDC, 9% (18/200) had a CAMPI. There was a higher prevalence of male CAMPI (17/169, 10%) compared to female CAMPI (1/31, 3%). The median time to identification of a CAMPI after initial IDC insertion was 12 weeks (2–136 weeks), but occurred as soon as 2 weeks. CAMPI formation was associated with IDC changes in the community, impaired mobility and congestive cardiac failure (CCF). CAMPI were mostly treated by conservative means given the frailty of the population. Conclusions: Poor mobility, community-managed IDCs, and CCF were all found to have statistically significant associations with the development of CAMPI. CAMPI represents an important and underserved iatrogenic complication within urology practice, and greater awareness is needed to prevent it in vulnerable patients with long-term IDCs

Structural controls on the location and distribution of CO2 emission at a natural CO2 spring in Daylesford, Australia

Secure storage of CO2 is imperative for carbon capture and storage technology, and relies on a thorough understanding of the mechanisms of CO2 retention and leakage. Observations at CO2 seeps around the world find that geological structures at a local and regional scale control the location, distribution and style of CO2 emission. Bedrock-hosted natural CO2 seepage is found in the Daylesford region in Victoria, Australia, where many natural springs contain high concentrations of dissolved CO2. Within a few meters of the natural Tipperary Mineral Spring, small CO2 bubble streams are emitted from bedrock into an ephemeral creek. We examine the relationship between structures in the exposed adjacent outcropping rocks and characteristics of CO2 gas leakage in the stream, including CO2 flux and the distribution of gas emissions. We find that degassing is clustered within ~1 m of a shale-sandstone geological contact. CO2 emission points are localised along bedding and fracture planes, and concentrated where these features intersect. The bubble streams were intermittent, which posed difficulties in quantifying total emitted CO2. Counterintuitively, the number of bubble streams and CO2 flux was greatest from shale dominated rather than the sandstone dominated features, which forms the regional aquifer. Shallow processes must be increasing the shale permeability, thus influencing the CO2 flow pathway and emission locations. CO2 seepage is not limited to the pool; leakage was detected in subaerial rock exposures, at the intersection of bedding and orthogonal fractures. These insights show the range of spatial scales of the geological features that control CO2 flow. Microscale features and near surface processes can have significant effect on the style and location and rates of CO2 leakage. The intermittency of the bubble streams highlights challenges around characterising and monitoring CO2 stores where seepage is spatially and temporally variable. CCS monitoring programmes must therefore be informed by understanding of shallow crustal processes and not simply the processes and pathways governing CO2 fluid flow at depth. Understanding how the CO2 fluids leaked by deep pathways might be affected by shallow processes will inform the design of appropriate monitoring tools and monitoring locations

Neurohormonal Regulation of IKs in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death

Heart failure (HF) results in sustained alterations in neurohormonal signaling, including enhanced signaling through the sympathetic nervous system and renin-angiotensin-aldosterone system pathways. While enhanced sympathetic nervous system and renin-angiotensin-aldosterone system activity initially help compensate for the failing myocardium, sustained signaling through these pathways ultimately contributes to HF pathophysiology. HF remains a leading cause of mortality, with arrhythmogenic sudden cardiac death comprising a common mechanism of HF-related death. The propensity for arrhythmia development in HF occurs secondary to cardiac electrical remodeling that involves pathological regulation of ventricular ion channels, including the slow component of the delayed rectifier potassium current, that contribute to action potential duration prolongation. To elucidate a mechanistic explanation for how HF-mediated electrical remodeling predisposes to arrhythmia development, a multitude of investigations have investigated the specific regulatory effects of HF-associated stimuli, including enhanced sympathetic nervous system and renin-angiotensin-aldosterone system signaling, on the slow component of the delayed rectifier potassium current. The objective of this review is to summarize the current knowledge related to the regulation of the slow component of the delayed rectifier potassium current in response to HF-associated stimuli, including the intracellular pathways involved and the specific regulatory mechanisms

Prevalence and sequelae of penile lichen sclerosus in males presenting for circumcision in regional Australia: a multicentre retrospective cohort study

Background: Lichen sclerosus (LS) in men commonly involves the external genitalia, with up to 20% of these patients developing urethral stricture disease, and a small group developing malignant transformation to penile squamous cell carcinoma (SCC). The objective of this study was to determine the prevalence of LS and its sequelae in males presenting for circumcision. Methods: A multicentre retrospective cohort study was conducted at 8 hospitals within 3 Australian regional centres. We identified males who underwent circumcision between January 2004 and November 2018 and obtained histological and clinical data. Histopathological confirmation of LS was the primary outcome. Development of urethral stricture disease and penile cancer were secondary outcomes. Results: Six hundred and eleven patients underwent circumcision, of which 313 (51.2%) had a specimen sent for histology. Of these, 199 (63.6%) had confirmed LS where the median age at diagnosis was 65 years [interquartile range (IQR), 40–77]. Even if the remainder of unsent specimens were free of LS, the prevalence would still be 32.6%. Amongst the patients with LS, 44 (22.1%) developed urethral strictures, 1 penile SCC (0.5%), and 1 penile intraepithelial neoplasia (0.5%). Conclusions: The prevalence of LS in patients undergoing circumcision where the foreskin was sent for histopathological review was 63.6%. In those with LS, the prevalence of urethral stricture disease was 22.1%

Prevalence and types of inconsistencies in clinical pharmacogenetic recommendations among major U.S. sources

Clinical implementation of pharmacogenomics (PGx) is slow. Previous studies have identified some inconsistencies among clinical PGx recommendations, but the prevalence and types of inconsistencies have not been comprehensively analyzed among major PGx guidance sources in the U.S. PGx recommendations from the Clinical Pharmacogenetics Implementation Consortium, U.S. Food and Drug Administration drug labels, and major U.S. professional medical organizations were analyzed through May 24, 2019. Inconsistencies were analyzed within the following elements: recommendation category; whether routine screening was recommended; and the specific biomarkers, variants, and patient groups involved. We identified 606 total clinical PGx recommendations, which contained 267 unique drugs. Composite inconsistencies occurred in 48.1% of clinical PGx recommendations overall, and in 93.3% of recommendations from three sources. Inconsistencies occurred in the recommendation category (29.8%), the patient group (35.4%), and routine screening (15.2%). In conclusion, almost one-half of clinical PGx recommendations from prominent U.S. guidance sources contain inconsistencies, which can potentially slow clinical implementation