Abelian and Non-Abelian Quantum Geometric Tensor

We propose a generalized quantum geometric tenor to understand topological quantum phase transitions, which can be defined on the parameter space with the adiabatic evolution of a quantum many-body system. The generalized quantum geometric tenor contains two different local measurements, the non-Abelian Riemannian metric and the non-Abelian Berry curvature, which are recognized as two natural geometric characterizations for the change of the ground-state properties when the parameter of the Hamiltonian varies. Our results show the symmetry-breaking and topological quantum phase transitions can be understood as the singular behavior of the local and topological properties of the quantum geometric tenor in the thermodynamic limit.Comment: 5 pages, 2 figure

Rehabilitation and Exercise Machine

An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness

Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model.

Human non‑small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist. Cucurbitacin E (CuE), an oxygenated tetracyclic triterpenoid isolated from plants particularly of the family Cucurbitaceae, has shown anti‑tumorigenic properties in several types of cancer, yet the mechanism remains unclear. Yes‑associated protein (YAP), a main mediator of the Hippo signaling pathway, promotes tumorigenesis, drug resistance and metastasis in human NSCLC. The present study was designed to ascertain whether CuE inhibits YAP and its downstream gene expression in the human NSCLC cell lines H2030‑BrM3 (K‑rasG12C mutation) and PC9‑BrM3 (EGFRΔexon19 mutation), which have high potential for brain metastasis. The efficacy of CuE in suppressing brain metastasis of H2030‑BrM3 cells in a murine model was also investigated. It was found that after CuE treatment in H2030‑BrM3 and PC9‑BrM3 cells, YAP protein expression was decreased, and YAP signaling GTIIC reporter activity and expression of the downstream genes CTGF and CYR61 were significantly (P<0.01) decreased. CuE treatment also reduced the migration and invasion abilities of the H2030‑BrM3 and PC9‑BrM3 cells. Finally, our in vivo study showed that CuE treatment (0.2 mg/kg) suppressed H2030‑BrM3 cell brain metastasis and that mice treated with CuE survived longer than the control mice treated with 10% DMSO (P=0.02). The present study is the first to demonstrate that CuE treatment inhibits YAP and the signaling downstream gene expression in human NSCLC in vitro, and suppresses brain metastasis of NSCLC in a murine model. More studies to verify the promising efficacy of CuE in inhibiting brain metastasis of NSCLC and various other cancers may be warranted

Rehabilitation and Exercise Machine

An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness

IMPROVED REHABILITATION AND EXERCISE MACHINE / MACHINE DE REEDUCATION ET D\u27EXERCICE AMELIOREE

An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness. An embodiment of the device includes a framework, a first and second crank arm, a first and second handle bar, a first and second foot pedal, a motor and pulley assembly, a first and second coupler link, and a motor controller with speed knob

Rehabilitation and Exercise Machine

An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness

A Practical Guide for X-Ray Diffraction Characterization of Ga(Al, In)N Alloys

Ga(In, Al)N alloys are used as an active layer or cladding layer in light emitting diodes and laser diodes. x-ray diffraction is extensively used to evaluate the crystalline quality, the chemical composition and the residual strain in Ga(Al,In)N thin films, which directly determine the emission wavelength and the device performance. Due to the minor mismatch in lattice parameters between Ga(Al, In)N alloy and a GaN virtual substrate, x-ray diffraction comes to a problem to separate the signal from Ga(Al,In)N alloy and GaN. We give a detailed comparison on different diffraction planes. In order to balance the intensity and peak separation between Ga(Al,In)N alloy and GaN, (0004) and (1015) planes make the best choice for symmetric scan and asymmetric scan, respectively.Comment: 9 pages, 5 figure

The Euler Number of Bloch States Manifold and the Quantum Phases in Gapped Fermionic Systems

We propose a topological Euler number to characterize nontrivial topological phases of gapped fermionic systems, which originates from the Gauss-Bonnet theorem on the Riemannian structure of Bloch states established by the real part of the quantum geometric tensor in momentum space. Meanwhile, the imaginary part of the geometric tensor corresponds to the Berry curvature which leads to the Chern number characterization. We discuss the topological numbers induced by the geometric tensor analytically in a general two-band model. As an example, we show that the zero-temperature phase diagram of a transverse field XY spin chain can be distinguished by the Euler characteristic number of the Bloch states manifold in a (1+1)-dimensional Bloch momentum space

Effects of social and outcome expectancies on hazardous drinking among Chinese university students: The mediating role of drinking motivations

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Background and Objectives: Based on the theory of reasoned action, the present study investigated the relative effects of drinking outcome expectancies and parental norms, as well as the mediating effect of drinking motivations, on hazardous drinking in Chinese university students. Method: A sample of Chinese university students in Hong Kong and Macao (N = 973, M=19.82, SD=1.57, 48.9% males), who reported drinking in the past 3 months, voluntarily completed an anonymous questionnaire. Path analysis was used to test the effects of the variables on hazardous drinking. Results: All the psychosocial variables showed positive correlations with hazardous drinking. In the path model, controlling for sex, parental norms had both direct and indirect effects on hazardous drinking through social and enhancement motivations. Courage had the strongest indirect effect on drinking behavior through social, enhancement, and coping motivations, whereas the relationship between tension reduction and hazardous drinking was mediated by enhancement and coping motivations. Sociality and sexuality only had indirect effect through social and coping motivations respectively. Negative outcome expectancies had no direct nor indirect effects on hazardous drinking. Conclusions: Perceived approval from parents and positive alcohol outcome expectancies may enhance individuals’ tendency to engage in hazardous drinking by increasing their motivation to drink to be social, for enjoyment, and to cope with problems. Parents should explicitly show their disapproval of their children’s drinking, and education efforts should focus on decreasing positive outcome expectancies and associated motivations for drinking among Chinese university students