Destruction of molecular compounds in gaseous and liquid medium in microwave discharge plasma

The paper presents the results of experimental studies of molecular destruction in gaseous and liquid medium using microwave discharge plasma at atmospheric pressure. As the gas medium hydrocarbon gas is used, the liquid medium were aqueous solutions of methylene blue and more complex organic compound in the form of humic substances. As a result of the destruction of hydrocarbon gas molecules in microwave discharge plasma new products such as hydrogen, ethylene, acetylene and carbon nanostructured material have been formed. In experiments on destruction of molecular compounds in aqueous organic solutions we used air, nitrogen and argon for plasma gases. It is shown that the process of molecular destruction in aqueous organic solutions in the microwave discharge plasma is based on oxidation-reduction reactions. It is found that the maximum efficiency of removal of organic compounds from the solution occurs when using air as the plasma gas

Influence of concentration modifier on the structure and functional properties of aluminum oxyhydroxide modified

Studying the properties of nanomaterials is an important task, but nanomaterials with desired properties is a promising direction. The aim of this work is to investigate the influence of the value of the concentration of the modifier (ions Mn{2+}) on the structural and functional properties of modified aluminum oxyhydroxide. In this paper, using methods such as the X-ray diffraction studies, differential thermal analysis, electron microscopy, chromatography. The paper found that increasing the concentration of the modifier result in significant changes in the morphology, the appearance of metallic aluminum, which is well seen on X-ray data samples. The influence of thermal effects on a modified aluminum oxyhydroxide argon. Set the phase transition temperatures in the synthesized samples. It is shown that with increasing sodeozhaniya manganese in the composition of the synthesized samples decreases the value of specific surface area. Study of the functional properties showed that the synthesized material has catalytic properties in the oxidation of methane. It is shown that the effective sample is a sample with a manganese content of 2.7 wt. %. By XRD results calcined in air samples modified aluminum oxyhydroxide was shown that only in the sample with a manganese content of 2.7 wt. % MnAl[2]O[4] phase is formed, which is catalytically active phase

Spin-glass ground state in a triangular-lattice compound YbZnGaO4_4

We report on comprehensive results identifying the ground state of a triangular-lattice structured YbZnGaO$_4$ to be spin glass, including no long-range magnetic order, prominent broad excitation continua, and absence of magnetic thermal conductivity. More crucially, from the ultralow-temperature a.c. susceptibility measurements, we unambiguously observe frequency-dependent peaks around 0.1 K, indicating the spin-glass ground state. We suggest this conclusion to hold also for its sister compound YbMgGaO$_4$, which is confirmed by the observation of spin freezing at low temperatures. We consider disorder and frustration to be the main driving force for the spin-glass phase.Comment: Version as accepted to PR

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling

It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio. Unlike other cells, neurons are abundant in the α3 isoform of Na+,K+-ATPase, whose affinity in rodents to ouabain is 104-fold higher compared to the α1 isoform. With these sharp differences in mind, we compared transcriptomic changes in rat cerebellum granule cells triggered by inhibition of α1- and α3-Na+,K+-ATPase isoforms. Inhibition of α1- and α3-Na+,K+-ATPase isoforms by 1 mM ouabain resulted in dissipation of transmembrane Na+ and K+ gradients and differential expression of 994 transcripts, whereas selective inhibition of α3-Na+,K+-ATPase isoform by 100 nM ouabain affected expression of 144 transcripts without any impact on the [Na+]i/[K+]i ratio. The list of genes whose expression was affected by 1 mM ouabain by more than 2-fold was abundant in intermediates of intracellular signaling and transcription regulators, including augmented content of Npas4, Fos, Junb, Atf3, and Klf4 mRNAs, whose upregulated expression was demonstrated in neurons subjected to electrical and glutamatergic stimulation. The role [Na+]i/[K+]i-mediated signaling in transcriptomic changes involved in memory formation and storage should be examined further

Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro

Although peroxisome proliferator-activated receptor gamma (PPARγ) agonist have been shown to inhibit hepatocellular carcinoma (HCC) development, the role of PPARγ in hepatocarcinogenesis remains unclear. We investigated the therapeutic efficacy of PPAR

IκBα polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese

<p>Abstract</p> <p>Background</p> <p>Nuclear factor of kappa B inhibitor alpha (IκBα) protein is implicated in regulating a variety of cellular process from inflammation to tumorigenesis. The objective of this study was to investigate the susceptibility of rs2233408 T/C genotype in the promoter region of <it>IκBα </it>to gastric cancer and the association of this polymorphism with clinicopathologic variables in gastric cancer patients.</p> <p>Methods</p> <p>A population-based case-control study was conducted between 1999 and 2006 in Guangdong Province, China. A total of 564 gastric cancer patients and 566 healthy controls were enrolled in this study. rs2233408 genotypes in <it>IκBα </it>were analyzed by TaqMan SNP genotyping assay.</p> <p>Results</p> <p>Both rs2233408 T homozygote (TT) and T heterozygotes (TC and TT) had significantly reduced gastric cancer risk (TT: OR = 0.250, 95% CI = 0.069-0.909, <it>P </it>= 0.035; TC and TT: OR = 0.721, 95% CI = 0.530-0.981, <it>P </it>= 0.037), compared with rs2233408 C homozygote (CC). rs2233408 T heterozygotes were significantly associated with reduced risk of intestinal-type gastric cancer with ORs of 0.648 (95% CI = 0.459-0.916, <it>P </it>= 0.014), but not with the diffuse or mix type of gastric cancer. The association between rs2233408 T heterozygotes and gastric cancer appeared more apparent in the older patients (age>40) (OR = 0.674, 95% CI = 0.484-0.939, <it>P </it>= 0.02). rs2233408 T heterozygotes was associated with non-cardiac gastric cancer (OR = 0.594, 95% CI = 0.411-0.859, <it>P </it>= 0.006), but not with cardiac gastric cancer. However, rs2233408 polymorphism was not associated with the prognosis of gastric cancer patients.</p> <p>Conclusions</p> <p><it>IκBα </it>rs2233408 T heterozygotes were associated with reduced risk of gastric cancer, especially for the development of certain subtypes of gastric cancer in Chinese population.</p