Frequency of Cutaneous Manifestations in Diabetic Patients in Endocrinology Clinic of Babol University of Medical Sciences

BACKGROUND AND OBJECTIVE: Diabetes is the most common endocrine disorder in the world. Understanding the cutaneous manifestations associated with diabetes can help in choosing the appropriate treatment approach in these patients. The aim of this study was to evaluate the frequency of cutaneous manifestations in diabetic patients referred to the endocrinology clinic of Babol University of Medical Sciences. METHODS: The present cross-sectional study was performed on 300 patients with diabetes referred to Rouhani Hospital in Babol in 2019. Age, gender, BMI, type and duration of diabetes, and patients’ diabetes control status (HbA1C) were recorded and patients were thoroughly examined by a dermatologist and divided into two groups of below and above 50 years. In terms of cutaneous manifestations, they were divided into two groups; with cutaneous manifestations and without cutaneous manifestations. FINDINGS: 293 patients (97.76%) had type 2 diabetes. The mean age of patients was 55±12 years and the mean duration of diabetes was 9.73±1.20 years. In this study, 130 patients (43%) had cutaneous lesions, of which 76 patients (58.5%) were female. Pruritus, acrochordon, cherry angioma, diabetic dermatopathy, fungal skin infections with frequencies of 25.7%, 21%, 14.3%, 6% and 5.7% were the most common skin disorders, respectively. 68 patients (69.4%) had skin manifestations and had diabetes for more than 10 years. There was a significant difference between the two groups of with and without cutaneous manifestations, gender and duration of diabetes (p<0.001). There was no significant difference between the mean age, BMI and HbA1C in the two groups (p=0.07, p=0.09 and p=0.11, respectively). CONCLUSION: The results of the study showed that pruritus and acrochordon are the most common cutaneous manifestations and long-term diabetes and female gender are the most important risk factors for cutaneous manifestations

Immersion and togetherness: How live visualization of audience engagement can enhance music events

This paper evaluates the influence of an additional visual aesthetic layer on the experience of concert goers during a live event. The additional visual layer incorporates musical features as well as bio-sensing data collected during the concert, which is coordinated by our audience engagement monitoring technology. This technology was used during a real Jazz concert. The collected measurements were used in an experiment with 32 participants, where two different forms of visualization were compared: one factoring in music amplitude, audience engagement collected by the sensors and the dynamic atmosphere of the event, the other one purely relying on the beat of the music. The findings indicate that the visual layer could add value to the experience if used during a live concert, providing a higher level of immersion and feeling of togetherness among the audience

Method for the identification of single mutations in large genomic regions using massive parallel sequencing

Map-based cloning of mutant genes is straightforward if the genome sequence and sufficient molecular markers are available. When a mutated gene in Arabidopsis causes a clear phenotype and is located in a genomic region where sufficient meiotic recombination takes place, the gene can be identified within 6-12 months. However, mutated genes that cause weak phenotypes are difficult to map to small genomic intervals due to faulty selection of F2 plants. Here, we describe a method that allows for rapid identification of roughly mapped genes by using a massive parallel sequencing strategy. A genomic region of 150 kb was PCR amplified in 7-17 kb pieces from an EMS Arabidopsis onset of leaf death ( old) mutant and its wild-type accession Landsberg erecta (Ler-0). Massive parallel sequencing and subsequent de novo assembly of the short sequences reliably identified 253 polymorphisms in a 110-kb region between the reference Col-0 and Ler-0 sequence. The analysis further revealed potential mutations in the old mutant of which one was confirmed to be present in the mutant. Thus the described method can be used for accelerating the map-based cloning of genes that cause weak phenotypes. An accompanying advantage is that the amplified fragments can be cloned and used to complement the mutant

New national and regional bryophyte records, 49

Peer reviewe

Analysis of spatial distribution of Tehran Metropolis urban services using models of urban planning

ABSTRACT: The process of spatial distribution of urban services in order to provide equitable access to opportunities and reduced regional disparities, and earning the highest citizen satisfaction are among the main challenges facing urban management. This requires knowledge of the current status of spatial distribution of public services in the city, followed by optimal resource allocation under varying circumstances. This analytical-comparative study aimed to investigate the spatial distribution of urban public services, and rank different districts of Tehran in terms of benefiting from public services. To achieve this goal, quantitative models of planning, including factor analysis, composite Human Development Index, taxonomical model and standardization method were used. For the final ranking of districts of Tehran, the sum of numerical value of each district was calculated in four ways. Based on this method, districts 1, 3, 22, 12 and 6 were ranked first to fifth, and districts 13, 10, 8, 17 and 14 were ranked last, respectively. Using cluster analysis model, different districts of Tehran metropolis were clustered on the basis of numerical value of districts in the models used. Based on above-mentioned results, districts 1, 3, 12, 22, 6 and 21, with a final score of 66 and above, included in the first cluster and identified as over-developed districts; and districts 14, 10, 8 and 17, with a final score of 13 or less, included in the fifth cluster and identified as disadvantaged districts

Analysis of spatial distribution of Tehran Metropolis urban services using models of urban planning

The process of spatial distribution of urban services in order to provide equitable access to opportunities and reduced regional disparities, and earning the highest citizen satisfaction are among the main challenges facing urban management. This requires knowledge of the current status of spatial distribution of public services in the city, followed by optimal resource allocation under varying circumstances. This analytical-comparative study aimed to investigate the spatial distribution of urban public services, and rank different districts of Tehran in terms of benefiting from public services. To achieve this goal, quantitative models of planning, including factor analysis, composite Human Development Index, taxonomical model and standardization method were used. For the final ranking of districts of Tehran, the sum of numerical value of each district was calculated in four ways. Based on this method, districts 1, 3, 22, 12 and 6 were ranked first to fifth, and districts 13, 10, 8, 17 and 14 were ranked last, respectively. Using cluster analysis model, different districts of Tehran metropolis were clustered on the basis of numerical value of districts in the models used. Based on above-mentioned results, districts 1, 3, 12, 22, 6 and 21, with a final score of 66 and above, included in the first cluster and identified as over-developed districts; and districts 14, 10, 8 and 17, with a final score of 13 or less, included in the fifth cluster and identified as disadvantaged districts

Hyphema Following Eye Trauma

Background and Objectives: Hyphema, the blood in the anterior eye chamber, can be caused by penetrating or blunt trauma or other causes. This study aimed at investigating the clinical features of 15 cases of traumatic Hyphema, having referred to ophthalmology ward of Shahid Beheshti hospital of Babol university of medical sciences.Methods: In this study the clinical characteristics of 15 patients with eye trauma-who had referred to Shahid Beheshti Hospital of Babol University of medical sciences during 2008-2009- were examined. In addition to eye trauma the selected patients had microscopic or macroscopic anterior eye chamber hemorrhages.Results: The mean age of patients was 25. 1 years. Eleven patients were male and four were female. Increased IOP was seen in 4 cases, three patients improved with drug therapy, but one patient needed surgery due to an increase in IOP and the re-bleeding. Regarding the degree of Hyphema, 4 cases were microscopic Hyphema , 2 cases were grade 1 of Hyphema, 3 cases were grade 2 of Hyphema, 3 cases were grade 3 of Hyphema , 2 cases grade 4 of Hyphema and one case was not assessable due to flattened anterior chamber, Visual Acuity was mostly poor at the beginning of admission which was significantly improved after treatment. On the whole, six patients underwent surgery.Conclusion: The results of this study show that patients with traumatic Hyphema usually have poor Visual Acuity at the beginning of admission, but the vision was relatively improved with early treatment in many cases. Therefore, proper and timely treatment is necessary in these patients