Query Expansion of Zero-Hit Subject Searches: Using a Thesaurus in Conjunction with NLP Techniques

The focus of our study is zero-hit queries in keyword subject searches and the effort of increasing recall in these cases by reformulating and, then, expanding the initial queries using an external source of knowledge, namely a thesaurus. To this end, the objectives of this study are twofold. First, we perform the mapping of query terms to the thesaurus terms. Second, we use the matched terms to expand the user’s initial query by taking advantage of the thesaurus relations and implementing natural language processing (NLP) techniques. We report on the overall procedure and elaborate on key points and considerations of each step of the process

An open-label study of herbal topical medication (Psirelax) for patients with chronic plaque psoriasis

Psirelax is an herbal topical medication indicated for the treatment ofpatients with psoriasis. Its efficacy was determined in an open-labelstudy in 22 patients (15 men, 7 women) with a mean age of 48.9±11.8years suffering from chronic plaque psoriasis. The patients weretreated by application of Psirelax twice a day for a period of 4 weeks.Clinical assessment was performed using the Psoriasis Area andSeverity Index (PASI) and the Beer-Sheva Psoriasis Severity Score(BPSS). The results shows that Psirelax was well tolerated and thereno local or systemic side effects. There was 59% reduction in PASI,from a mean of 5.9 ± 4.0 before treatment to 2.4 ± 2.4 after treatment(p<0.001). In 8 patients (36%) PASI decreased in more than 75%(PASI75). In 16 patients (73%) PASI decreased in more than 50%(PASI50). Application of Psirelax was associated with a decrease indisease severity, as assessed by the patients and physicians. It isconcluded that Psirelax treatment was well tolerated in patients withchronic plaque psoriasis

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways.

Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium (DSS)-induced colitis via its potential antioxidant capacity, and by inhibiting the activation of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome. This study aims to clarify the nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) pathway pharmacological activation and anti-inflammatory effect by DMF, through focusing on other crucial antioxidant enzymes and inflammatory mediator, including glutamate-cysteine ligase catalytic subunit (GCLC), glutathione peroxidase (GPX) and cyclooxygenase-2 (COX-2), in a DSS-induced colitis mouse model. The oral administration of DMF attenuated the shortening of colons and alleviated colonic inflammation. Furthermore, the expression of key antioxidant enzymes, including GCLC and GPX, in the colonic tissue were significantly increased by DMF administration. In addition, protein expression of the inflammatory mediator, COX-2, was reduced by DMF administration. Our results suggest that DMF alleviates DSS-induced colonic inflammatory damage, likely via up-regulating GCLC and GPX and down-regulating COX-2 protein expression in colonic tissue

Eye of the Beholder: The individual and dyadic contributions of empathic accuracy and perceived empathic effort to relationship satisfaction

This study examined links between two distinct facets of empathy – empathic accuracy and perceived empathic effort – and one’s own and one’s partner’s relationship satisfaction. Using a video recall procedure, participants (N = 156 couples in committed relationships) reported on their own emotions and their perceptions of partners’ emotions and partners’ empathic intentions during moments of high affect in laboratory-based discussions of upsetting events. Partners’ data were correlated as a measure of how accurately they were able to read what the other was feeling and to what degree they felt the other was trying to be empathic at those moments. The perception of empathic effort by one’s partner was more strongly linked with both men’s and women’s relationship satisfaction than empathic accuracy. Men’s relationship satisfaction was related to the ability to read their partners’ positive emotions accurately, whereas women’s relationship satisfaction was related to their partners’ ability to read women’s negative emotions accurately. Women’s ability to read their husbands’ negative emotions was positively linked to both men’s and women’s relationship satisfaction. Findings suggest that the perception of a partner’s empathic effort – as distinct from empathic accuracy – is uniquely informative in understanding how partners may derive relationship satisfaction from empathic processes. When working with couples in treatment, heightening partners’ perceptions of each other’s empathic effort, and helping partners learn to demonstrate effort, may represent particularly powerful opportunities for improving satisfaction in relationships

Sources of somatization: Exploring the roles of insecurity in relationships and styles of anger experience and expression

Research has shown strong connections between insecure attachment in close relationships and somatization. In addition, studies have demonstrated connections between somatic symptoms and anger experience and expression. In this study, we integrate perspectives from these two literatures by testing the hypothesis that proneness to anger and suppression of anger mediate the link between insecurity in relationships and somatization. Between 2000 and 2003, a community-based sample of 101 couples in a large U.S. city completed self-report measures, including the Somatic Symptom Inventory, the Relationship Scales Questionnaire, the Multidimensional Anger Inventory, the Revised Conflict Tactics Scale, and the Beck Depression Inventory. Controlling for age, income, and recent intimate partner violence, analyses showed that the link between insecure attachment and somatization was partially mediated by anger proneness for men and by anger suppression for women. Findings are consistent with the hypothesis that men who are insecurely attached are more prone to experience anger that in turn fosters somatization. For women, findings suggest that insecure attachment may influence adult levels of somatization by fostering suppression of anger expression. Specific clinical interventions that help patients manage and express angry feelings more adaptively may reduce insecurely attached individuals’ vulnerability to medically unexplained somatic symptoms

Task search in a human computation market

In order to understand how a labor market for human computation functions, it is important to know how workers search for tasks. This paper uses two complementary methods to gain insight into how workers search for tasks on Mechanical Turk. First, we perform a high frequency scrape of 36 pages of search results and analyze it by looking at the rate of disappearance of tasks across key ways Mechanical Turk allows workers to sort tasks. Second, we present the results of a survey in which we paid workers for self-reported information about how they search for tasks. Our main findings are that on a large scale, workers sort by which tasks are most recently posted and which have the largest number of tasks available. Furthermore, we find that workers look mostly at the first page of the most recently posted tasks and the first two pages of the tasks with the most available instances but in both categories the position on the result page is unimportant to workers. We observe that at least some employers try to manipulate the position of their task in the search results to exploit the tendency to search for recently posted tasks. On an individual level, we observed workers searching by almost all the possible categories and looking more than 10 pages deep. For a task we posted to Mechanical Turk, we confirmed that a favorable position in the search results do matter: our task with favorable positioning was completed 30 times faster and for less money than when its position was unfavorable.National Science Foundation (U.S.). Integrative Graduate Education and Research Traineeship (Multidisciplinary Program in Inequality & Social Policy) (Grant Number 033340

Eye of the Beholder: The individual and dyadic contributions of empathic accuracy and perceived empathic effort to relationship satisfaction

This study examined links between two distinct facets of empathy – empathic accuracy and perceived empathic effort – and one’s own and one’s partner’s relationship satisfaction. Using a video recall procedure, participants (N = 156 couples in committed relationships) reported on their own emotions and their perceptions of partners’ emotions and partners’ empathic intentions during moments of high affect in laboratory-based discussions of upsetting events. Partners’ data were correlated as a measure of how accurately they were able to read what the other was feeling and to what degree they felt the other was trying to be empathic at those moments. The perception of empathic effort by one’s partner was more strongly linked with both men’s and women’s relationship satisfaction than empathic accuracy. Men’s relationship satisfaction was related to the ability to read their partners’ positive emotions accurately, whereas women’s relationship satisfaction was related to their partners’ ability to read women’s negative emotions accurately. Women’s ability to read their husbands’ negative emotions was positively linked to both men’s and women’s relationship satisfaction. Findings suggest that the perception of a partner’s empathic effort – as distinct from empathic accuracy – is uniquely informative in understanding how partners may derive relationship satisfaction from empathic processes. When working with couples in treatment, heightening partners’ perceptions of each other’s empathic effort, and helping partners learn to demonstrate effort, may represent particularly powerful opportunities for improving satisfaction in relationships

Sources of somatization: Exploring the roles of insecurity in relationships and styles of anger experience and expression

Research has shown strong connections between insecure attachment in close relationships and somatization. In addition, studies have demonstrated connections between somatic symptoms and anger experience and expression. In this study, we integrate perspectives from these two literatures by testing the hypothesis that proneness to anger and suppression of anger mediate the link between insecurity in relationships and somatization. Between 2000 and 2003, a community-based sample of 101 couples in a large U.S. city completed self-report measures, including the Somatic Symptom Inventory, the Relationship Scales Questionnaire, the Multidimensional Anger Inventory, the Revised Conflict Tactics Scale, and the Beck Depression Inventory. Controlling for age, income, and recent intimate partner violence, analyses showed that the link between insecure attachment and somatization was partially mediated by anger proneness for men and by anger suppression for women. Findings are consistent with the hypothesis that men who are insecurely attached are more prone to experience anger that in turn fosters somatization. For women, findings suggest that insecure attachment may influence adult levels of somatization by fostering suppression of anger expression. Specific clinical interventions that help patients manage and express angry feelings more adaptively may reduce insecurely attached individuals’ vulnerability to medically unexplained somatic symptoms

Links between childhood physical abuse and intimate partner aggression: The mediating role of anger expression

Research linking childhood physical abuse (CPA) and adult intimate partner aggression (IPA) has focused on individuals without sufficient attention to couple processes. In this study, 109 couples reported on histories of CPA, IPA, and anger expression. Actor-Partner Interdependence Modeling was used to examine links between CPA and revictimization and perpetration of IPA, with anger suppression as a potential mediator. Women’s CPA histories were associated with more physical aggression towards and more revictimization by partners. Men’s CPA histories were only associated at the trend level with their revictimization. Anger suppression fully mediated the link between women’s CPA and both revictimization and perpetration of IPA. Findings suggest that women with CPA histories are more prone to suppress anger, which leaves them at greater risk for revictimization and perpetration of IPA

Security of attachment to spouses in late life: Concurrent and prospective links with cognitive and emotional wellbeing

Social ties are powerful predictors of late-life health and well-being. Although many adults maintain intimate partnerships into late life, little is known about mental models of attachment to spouses and how they influence aging. A total of 81 elderly heterosexual couples (162 individuals) were interviewed to examine the structure of attachment security to their partners; respondents also completed measures of cognition and well-being concurrently and 2.5 years later. Factor analysis revealed a single factor for security of attachment. Higher security was linked concurrently with greater marital satisfaction, fewer depressive symptoms, better mood, and less frequent marital conflicts. Greater security predicted lower levels of negative affect, less depression, and greater life satisfaction 2.5 years later. For women, greater security predicted better memory 2.5 years later and attenuated the link between frequency of marital conflict and memory deficits. Late in life, mental models of attachment to partners are linked to well-being concurrently and over time