Global imbalances and current account imbalances.

As the global economy gradually recovers from the severe recession, the possible risks of unsustainable global imbalances are receiving renewed attention. In assessing global imbalances, it is important to avoid excessively focusing on current account imbalances per se. Rather, the focus should be on the root causes of the imbalance and whether they may become sources of unsustainable financial imbalances. The recent financial crisis, as well as Japan’s past experience in the 1980s, highlight the importance of information which cannot necessarily be obtained from current account statistics. Unsustainable financial imbalances can be better captured through information such as the build-up of leverage, gross cross-border capital flows, risk pricing in financial markets, and the extent of currency and maturity mismatches in the financial system. Through careful assessment of such elements central banks and other authorities will be able to assess whether current account imbalances are a reflection of the build-up of domestic financial imbalances. In formulating macroeconomic policy, the traditional emphasis was to ensure domestic stability or to put one’s house in order. However, with the deepening of globalisation, the simple sum of each country’s policy action may not necessarily achieve an optimal outcome at the global level. It has become ever more important for countries to review the spillover effects of their policies which will also reverberate back to each country through economic and financial interlinkages.

Família defensiva de peptídeos antimicrobianos em Urochloa.

O capim-braquiária é muito utilizado no Brasil, principalmente no cerrado, como forrageira devido a sua alta adaptabilidade a variados solos, como solos ácidos ou pobres em nutrientes; e apresenta alta cobertura e produção de biomassa. Os peptídeos antimicrobianos são moléculas proteicas pequenas produzidas por todos os seres vivos como parte do sistema imune inato para combater infecções e patógenos. Peptídeos antimicrobianos vegetais possuem um amplo espectro de atividades antimicrobianas contra fitopatógenos e a grande maioria deles é ativa contra fungos, enquanto alguns são inibidores de bactérias e insetos herbívoros. Deste modo, o objetivo deste trabalho foi verificar e identificar a presença de peptídeos antimicrobianos da família das defensinas em U. decumbens por meio da comparação entre as sequências do transcriptoma da planta contra as sequências de aminoácidos de peptídeos antimicrobianos. O transcriptoma da planta foi fornecido pela EMBRAPA Gado de Corte (Campo Grande, MS), obtido pela extração de RNA de plantas expostas a condições de estresse (com alumínio) e sem estresse (sem alumínio). As sequências dos peptídeos antimicrobianos foram baixadas do banco de dados online CAMP e foram formatadas em FASTA em um banco local no computador da FCBA, UFGD. Foi utilizado o blast local para fazer o alinhamento entre os 164.920 transcritos únicos da U. decumbens e as 5.906 sequências de peptídeos antimicrobianos. Deste alinhamento obteve-se 3.161 similaridades com 251 peptídeos diferentes. Para a análise dos resultados utilizou-se o MySQL, separando-os em famílias de acordo com a classificação do banco de dados CAMP e selecionando um grupo amostral para a construção das árvores filogenéticas. A partir desta análise, obteve-se 261 similaridades com 52 peptídeos diferentes dentro da família das defensinas. A maioria dos peptídeos antimicrobianos identificados possui atividade antifúngica ou antimicrobiana, e são de origem vegetal o que condiz com os transcritos da gramínea

A new half-metallic ferromagnet K2Cr8O16 predicted by an ab-initio electronic structure calculation

The first-principles electronic structure calculation is carried out to predict that a chromium oxide K2Cr8O16 with the hollandite-type crystal structure should be a new half-metallic ferromagnet. We compare our results with recent experimental data which indicate the ferromagnetic-metal to ferromagnetic-insulator transition at T ∼ 90 K, as well as the paramagnetic-metal to ferromagnetic-metal transition at T ∼ 180 K. Based on the calculated electronic structures, we argue that the double-exchange mechanism is responsible for the observed saturated ferromagnetism and the formation of the incommensurate, long-wavelength density wave of spinless fermions caused by the Fermi-surface nesting may be the origin of the opening of the charge gap.Ministry of Education, Culture, Sports, Science and Technology of Japa

Bessel bridges decomposition with varying dimension. Applications to finance

We consider a class of stochastic processes containing the classical and well-studied class of Squared Bessel processes. Our model, however, allows the dimension be a function of the time. We first give some classical results in a larger context where a time-varying drift term can be added. Then in the non-drifted case we extend many results already proven in the case of classical Bessel processes to our context. Our deepest result is a decomposition of the Bridge process associated to this generalized squared Bessel process, much similar to the much celebrated result of J. Pitman and M. Yor. On a more practical point of view, we give a methodology to compute the Laplace transform of additive functionals of our process and the associated bridge. This permits in particular to get directly access to the joint distribution of the value at t of the process and its integral. We finally give some financial applications to illustrate the panel of applications of our results

AC resistivity of d-wave ceramic superconductors

We model d-wave ceramic superconductors with a three-dimensional lattice of randomly distributed $\pi$ Josephson junctions with finite self-inductance. The linear and nonlinear ac resistivity of the d-wave ceramic superconductors is obtained as function of temperature by solving the corresponding Langevin dynamical equations. We find that the linear ac resistivity remains finite at the temperature $T_p$ where the third harmonics of resistivity has a peak. The current amplitude dependence of the nonlinear resistivity at the peak position is found to be a power law. These results agree qualitatively with experiments. We also show that the peak of the nonlinear resistivity is related to the onset of the paramagnetic Meissner effect which occurs at the crossover temperature $T_p$, which is above the chiral glass transition temperature $T_{cg}$.Comment: 7 eps figures, Phys. Rev. B (in press

Stability of the Magnetopause of Disk-Accreting Rotating Stars

We discuss three modes of oscillation of accretion disks around rotating magnetized neutron stars which may explain the separations of the kilo-Hertz quasi periodic oscillations (QPO) seen in low mass X-ray binaries. The existence of these compressible, non-barotropic magnetohydrodynamic (MHD) modes requires that there be a maximum in the angular velocity $\Omega_\phi(r)$ of the accreting material larger than the angular velocity of the star $\Omega_*$, and that the fluid is in approximately circular motion near this maximum rather than moving rapidly towards the star or out of the disk plane into funnel flows. Our MHD simulations show this type of flow and $\Omega_\phi(r)$ profile. The first mode is a Rossby wave instability (RWI) mode which is radially trapped in the vicinity of the maximum of a key function $g(r){\cal F}(r)$ at $r_{R}$. The real part of the angular frequency of the mode is $\omega_r=m\Omega_\phi(r_{R})$, where $m=1,2...$ is the azimuthal mode number. The second mode, is a mode driven by the rotating, non-axisymmetric component of the star's magnetic field. It has an angular frequency equal to the star's angular rotation rate $\Omega_*$. This mode is strongly excited near the radius of the Lindblad resonance which is slightly outside of $r_R$. The third mode arises naturally from the interaction of flow perturbation with the rotating non-axisymmetric component of the star's magnetic field. It has an angular frequency $\Omega_*/2$. We suggest that the first mode with $m=1$ is associated with the upper QPO frequency, $\nu_u$; that the nonlinear interaction of the first and second modes gives the lower QPO frequency, $\nu_\ell =\nu_u-\nu_*$; and that the nonlinear interaction of the first and third modes gives the lower QPO frequency $\nu_\ell=\nu_u-\nu_*/2$, where $\nu_*=\Omega_*/2\pi$.Comment: 10 pages, 7 figure

Reducing nonideal to ideal coupling in random matrix description of chaotic scattering: Application to the time-delay problem

We write explicitly a transformation of the scattering phases reducing the problem of quantum chaotic scattering for systems with M statistically equivalent channels at nonideal coupling to that for ideal coupling. Unfolding the phases by their local density leads to universality of their local fluctuations for large M. A relation between the partial time delays and diagonal matrix elements of the Wigner-Smith matrix is revealed for ideal coupling. This helped us in deriving the joint probability distribution of partial time delays and the distribution of the Wigner time delay.Comment: 4 pages, revtex, no figures; published versio

In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers

Citation: Wakizaka, M., Eshima, H., Tanaka, Y., Shirakawa, H., Poole, D. C., & Kano, Y. (2017). In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers. Physiological Reports, 5(5), 10. doi:10.14814/phy2.13180In contrast to cardiomyocytes, store overload-induced calcium ion (Ca2+) release (SOICR) is not considered to constitute a primary Ca2+ releasing system from the sarcoplasmic reticulum (SR) in skeletal muscle myocytes. In the latter, voltage-induced Ca2+ release (VICR) is regarded as the dominant mechanism facilitating contractions. Any role of the SOICR in the regulation of cytoplasmic Ca2+ concentration ([Ca2+](i)) and its dynamics in skeletal muscle in vivo remains poorly understood. By means of in vivo single fiber Ca2+ microinjections combined with bioimaging techniques, we tested the hypothesis that the [Ca2+](i) dynamics following Ca2+ injection would be amplified and fiber contraction facilitated by SOICR. The circulation-intact spinotrapezius muscle of adult male Wistar rats (n = 34) was exteriorized and loaded with Fura-2 AM to monitor [Ca2+](i) dynamics. Groups of rats underwent the following treatments: (1) 0.02, 0.2, and 2.0 mmol/L Ca2+ injections, (2) 2.0 mmol/L Ca2+ with inhibition of ryanodine receptors (RyR) by dantrolene sodium (DAN), and (3) 2.0 mmol/L Ca2+ with inhibition of SR Ca2+ ATPase (SERCA) by cyclopiazonic acid (CPA). A quantity of 0.02 mmol/L Ca2+ injection yielded no detectable response, whereas peak evoked [Ca2+](i) increased 9.9 +/- 1.8% above baseline for 0.2 mmol/L and 23.8 c 4.3% (P < 0.05) for 2.0 mmol/L Ca2+ injections. The peak [Ca2+](i) in response to 2.0 mmol/L Ca2+ injection was largely abolished by DAN and CPA (-85.8%, -71.0%, respectively, both P < 0.05 vs. unblocked) supporting dependence of the [Ca2+](i) dynamics on Ca2+ released by SOICR rather than injected Ca2+ itself. Thus, this investigation demonstrates the presence of a robust SR-evoked SOICR operant in skeletal muscle in vivo