Initial clinical evaluation of observer performance using a tablet computer with a 4K high-resolution display for detection of breast cancer by digital mammography

Purpose:To compare observer performance using medical‐purpose 5‐megapixel liquid crystal display monitors (5‐MP LCDs) and a tablet PC with a 4K high‐resolution display for detection of breast cancer by digital mammography. Materials and methods: Mammograms from 40 patients with primary breast cancer (18 mass, 16 microcalcifications, 3 artificial distortions, and 3 focal asymmetries) and 60 control patients were consecutively collected. Four experienced radiologists assessed 100 mammograms to rate using the BI‐RADS lexicon. The BI‐RADS assessments were subjected to receiver operating characteristic (ROC) curve analysis. Also, the observers assessed the image quality in terms of brightness, contrast, sharpness, and noise using 5‐step Likert scale. Results: The average under the curve (AUC) values for use of the 5‐MP LCDs and 4K monitors were 0.921 and 0.936; the difference between them was small and not significant. In terms of image quality, the 4K was rated better for brightness, contrast, and sharpness. Conclusion: Observer performance for detecting breast cancer on a 4K tablet PC with a high‐resolution display is similar to that using a 5‐MP LCD. This appears adequate for displaying mammograms of diagnostic quality and could be useful for patient consultations, clinical demonstrations, or educational and teaching purposes

Three-Dimensional Image Fusion of SPECT and CT Scans for Locating Sentinel Lymph Nodes in Malignant Melanomas

Image fusion software can derive a fusion image from single photon emission computed tomography and computed tomography scans. We applied a three-dimensional fusion image to detect sentinel lymph nodes (SLNs) in 3 patients with malignant melanomas of the lumbar, vulvar and head region, respectively. During each operation, we detected SLNs at the expected site, as indicated by the fusion images. The three-dimensional image fusion could thus be confirmed as a simple and helpful method for precisely localizing SLNs in these patients

Comparison of Epirubicin-Iodized Oil Suspension and Emulsion for Transcatheter Arterial Chemoembolization in VX2 Tumor

To compare the antitumor efficacy and safety of transcatheter arterial chemoembolization (TACE) by epirubicin suspension (epirubicin suspension: epirubicin-iodized oil mixture without solution) to that by epirubicin emulsion (epirubicin emulsion: epirubicin-iodized oil mixture with solution), the efficacy of treatment by administration of either an epirubicin suspension or emulsion was examined in an animal model. Changes in plasma epirubicin concentration were compared over 24 h immediately after treatment, and enhanced ultrasonographic and histopathological analysis subsequently conducted 7 days after treatment to determine the growth ratio and proportion of viable tumor cells. The growth ratio and proportion of viable tumor cells were found to be significantly lower in the suspension group than in the emulsion group while the plasma epirubicin concentration was found to be significantly higher in the suspension group than in the emulsion group. These results indicate that administration of an epirubicin suspension is a superior form of TACE compared to that of administration of an epirubicin emulsion

T2-Weighted Cardiac Magnetic Resonance Imaging of Edema in Myocardial Diseases

The purpose of this paper is to describe imaging techniques and findings of T2-weighted magnetic resonance imaging (MRI) of edema in myocardial diseases. T2-weighted cardiac MRI is acquired by combining acceleration techniques with motion and signal suppression techniques. The MRI findings should be interpreted based on coronary artery supply, intramural distribution, and comparison with delayed-enhancement MRI. In acute myocardial diseases, such as acute myocardial infarction and myocarditis, the edema is larger than myocardial scarring, whereas the edema can be smaller than the scarring in some types of nonischemic cardiomyopathy, including hypertrophic cardiomyopathy. T2-weighted MRI of edema identifies myocardial edema associated with ischemia, inflammation, vasculitis, or intervention in the myocardium and provides information complementary to delayed-enhancement MRI

Peripheral Coronary Artery Circulatory Dysfunction in Remote Stage Kawasaki Disease Patients Detected by Adenosine Stress 13N-Ammonia Myocardial Perfusion Positron Emission Tomography

博士（医学）乙日本医科大学202

Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group

金沢大学大学院医学系研究科がん制御