Amano, Yasuo

Kiriyama, Tomonari

Kobayashi, Yasuhiro

Kumita, Shinichiro

Sekine, Tetsuro

Tachi, Masaki

English

PubMed

Yasuo Amano

Tomonari Kiriyama

Masaki Tachi

Yasuhiro Kobayashi

Tetsuro Sekine

Shinichiro Kumita

Springer - Publisher Connector

POSTER PRESENTATION Open Access
Simultaneous assessment of myocardial scar and
coronary artery disease by navigator-gated 3D
fat-suppressed delayed-enhancement CMR:
comparison with 2D delayed-enhancement CMR,
CT and CAG
Yasuo Amano*, Tomonari Kiriyama, Masaki Tachi, Yasuhiro Kobayashi, Tetsuro Sekine, Shinichiro Kumita
From 15th Annual SCMR Scientific Sessions
Orlando, FL, USA. 2-5 February 2012
Summary
The aim of this study was to assess the feasibility of
navigator-gated 3D fat-suppressed delayed-enhancement
CMR (DE-CMR) for simultaneous assessment of the
myocardial scar and coronary artery disease, by compar-
ing with 2D DE-CMR, CT, and CAG.
Background
Simultaneous assessment of myocardial scar or perfu-
sion reduction and coronary artery stenosis is currently
performed by side-by-side comparison or image fusion
using coronary CTA and myocardial perfusion study,
but the misregistration and differences in spatial resolu-
tion between imaging methods can be problematic. A
CMR technique that can visualize both myocardial scar
and coronary artery disease during a single examination
may resolve this problem.
Methods
Sixteen patients underwent a navigator-gated 3D fat-
suppressed DE-CMR using a 3.0T imager. The spatial
resolution of this imaging was 1.5x1.25x3.0-3.4 mm3
before an interpolation. Inversion recovery and spec-
trally-selective pulses were used to suppress normal
myocardial and epicardial fat signals, respectively. The
ability of the navigator-gated 3D fat-suppressed DE-
CMR to detect myocardial scar was compared with that
of 2D DE-CMR. The signal reduction of coronary artery
on the 3D DE-CMR was compared with calcified
plaques on CT (n = 13) and significant stenosis (> 75%)
on CAG (n = 8). The relationship between myocardial
scar and coronary arteries was also assessed in six
patients with ischemic cardiomyopathies.
Results
Twenty-five myocardial scars on 2D DE-CMR, 66 cor-
onary calcified lesions on CT, and six coronary stenoses
on CAG were investigated in 16 patients. The navigator-
gated 3D fat-suppressed DE-CMR detected 25 (92.6%)
scars, 43 (65.1%) arterial signal reduction, and three
(50%) coronary artery stenoses. When excluding the
coronary arteries that were affected by respiratory arti-
facts, 84.3% of coronary artery diseases were detected by
the 3D-CMR. This imaging showed the diffuse stenoses
of coronary arteries, comparable to diffuse calcified pla-
ques, in the patients with ischemic cardiomyopathy.
Conclusions
Navigator-gated 3D fat-suppressed DE-CMR was feasi-
ble for simultaneous assessment of the myocardial scar
and coronary arteries with calcified plaques.
Funding
No disclosure for this presentation.
Published: 1 February 2012
Nippon Medical School, Tokyo, Japan
Amano et al. Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):P302
http://www.jcmr-online.com/content/14/S1/P302
© 2012 Amano et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons
Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in
any medium, provided the original work is properly cited.
doi:10.1186/1532-429X-14-S1-P302
Cite this article as: Amano et al.: Simultaneous assessment of
myocardial scar and coronary artery disease by navigator-gated 3D fat-
suppressed delayed-enhancement CMR: comparison with 2D delayed-
enhancement CMR, CT and CAG. Journal of Cardiovascular Magnetic
Resonance 2012 14(Suppl 1):P302.
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Figure 1 Navigator-gated 3D fat-suppressed DE-CMR shows
myocardial scar following infarction.
Figure 2 Navigator-gated 3D fat-suppressed DE-CMR shows signal
reduction of coronary arteries simultaneously.
Amano et al. Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):P302
http://www.jcmr-online.com/content/14/S1/P302
Page 2 of 2


Simultaneous assessment of myocardial scar and coronary artery disease by navigator-gated 3D fat-suppressed delayed-enhancement CMR: comparison with 2D delayed-enhancement CMR, CT and CAG

Simultaneous assessment of myocardial scar and coronary artery disease by navigator-gated 3D fat-suppressed delayed-enhancement CMR: comparison with 2D delayed-enhancement CMR, CT and CAG

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