Towards Realizing a Quantum Memory for a Superconducting Qubit: Storage and Retrieval of quantum states

We have built a hybrid system composed of a superconducting flux qubit (the processor) and an ensemble of nitrogen-vacancy centers in diamond (the memory) that can be directly coupled to one another and demonstrated how information can be transferred from the flux qubit to the memory, stored and subsequently retrieved. We have established the coherence properties of the memory, and succeeded in creating an entangled state between the processor and memory, demonstrating how the entangled state's coherence is preserved. Our results are a significant step towards using an electron spin ensemble as a quantum memory for superconducting qubits.Comment: 5 pages, 3 figure

Optimization temperature sensitivity using the optically detected magnetic resonance spectrum of a nitrogen-vacancy center ensemble

Temperature sensing with nitrogen vacancy (NV) centers using quantum techniques is very promising and further development is expected. Recently, the optically detected magnetic resonance (ODMR) spectrum of a high-density ensemble of the NV centers was reproduced with noise parameters [inhomogeneous magnetic field, inhomogeneous strain (electric field) distribution, and homogeneous broadening] of the NV center ensemble. In this study, we use ODMR to estimate the noise parameters of the NV centers in several diamonds. These parameters strongly depend on the spin concentration. This knowledge is then applied to theoretically predict the temperature sensitivity. Using the diffraction-limited volume of 0.1 micron^3, which is the typical limit in confocal microscopy, the optimal sensitivity is estimated to be around 0.76 mK/Hz^(1/2) with an NV center concentration of 5.0e10^17/cm^3. This sensitivity is much higher than previously reported sensitivities, demonstrating the excellent potential of temperature sensing with NV centers.Comment: 17 pages, 4 figures, 1 tabl

Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer

Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells. Here we show a critical role of transactivation of BIG3, brefeldin A-inhibited guanine nucleotide-exchange protein 3, in activation of the estrogen/ER signaling in breast cancer cells. Knocking-down of BIG3 expression with small-interfering RNA (siRNA) drastically suppressed the growth of breast cancer cells. Subsequent co-immunoprecipitation and immunoblotting assays revealed an interaction of BIG3 with prohibitin 2/repressor of estrogen receptor activity (PHB2/REA). When BIG3 was absent, stimulation of estradiol caused the translocation of PHB2/REA to the nucleus, enhanced the interaction of PHB2/REA and ER[alpha], and resulted in suppression of the ER[alpha]; transcriptional activity. On the other hand, when BIG3 was present, BIG3 trapped PHB2/REA in cytoplasm and inhibited its nuclear translocation, and caused enhancement of ER[alpha]; transcriptional activity. Our results imply that BIG3 overexpression is one of the important mechanisms causing the activation of the estrogen/ER[alpha]; signaling pathway in the hormone-related growth of breast cancer cells

Severe Gummy Smile with Class II Malocclusion Treated with LeFort I Osteotomy Combined with Horseshoe Osteotomy and Intraoral Vertical Ramus Osteotomy

In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFort I osteotomy combined with a horseshoe osteotomy was used for the superior repositioning of the maxilla;then, an intraoral vertical ramus osteotomy (IVRO) and genioplasty were performed for mandibular advancement. The maxilla was acceptably impacted 8mm at the first incisor and 5mm at the first molar. Both the occlusion and facial appearance were significantly improved by this surgical-orthodontic treatment. Our results suggest that the combination of a horseshoe osteotomy with a LeFort I osteotomy is a useful technique for reliable superior repositioning of the maxilla

Chaotic Properties of the Arctic Oscillation Index

In this letter, we investigate nonlinear properties of the underlying dynamics for the Arctic Oscillation Index (AOI). First, we develop a test statistic for surrogate data analysis so that we can deal with the high-dimensionality of AOI. Second, we validate the test statistic with toy models. Then, by applying the proposed new test statistic with surrogate data to the dataset of AOI for the last 60 years, we show that AOI is nonlinear with determinism beyond pseudo-periodicity. These results mean that the underlying dynamics of AOI is consistent with deterministic chaos, implying that it is predictable in a short-term but not in a long-term

Experimental Investigation on the Wave Rotor Constant Volume Combustor

A wave rotor constant volume combustor was designed and built as a collaborative work of Rolls-Royce, Indiana University-Purdue University Indianapolis (IUPUI), and Purdue University. The experiment was designed to operate at rotational speeds of up to 4,200 rpm with air mass flow rates of approximately 18 lbm per second. Initial tests were conducted at 2,100 rpm with ethylene as fuel. The rig was operated with different fuel injection schemes to investigate operational characteristics of the combustor. Successful combustion and pressure gain were achieved over a range of operating conditions

Sensitivity analyses of OH missing sinks over Tokyo metropolitan area in the summer of 2007

OH reactivity is one of key indicators which reflect impacts of photochemical reactions in the atmosphere. An observation campaign has been conducted in the summer of 2007 at the heart of Tokyo metropolitan area to measure OH reactivity. The total OH reactivity measured directly by the laser-induced pump and probe technique was higher than the sum of the OH reactivity calculated from concentrations and reaction rate coefficients of individual species measured in this campaign. And then, three-dimensional air quality simulation has been conducted to evaluate the simulation performance on the total OH reactivity including "missing sinks", which correspond to the difference between the measured and calculated total OH reactivity. The simulated OH reactivity is significantly underestimated because the OH reactivity of volatile organic compounds (VOCs) and missing sinks are underestimated. When scaling factors are applied to input emissions and boundary concentrations, a good agreement is observed between the simulated and measured concentrations of VOCs. However, the simulated OH reactivity of missing sinks is still underestimated. Therefore, impacts of unidentified missing sinks are investigated through sensitivity analyses. In the cases that unknown secondary products are assumed to account for unidentified missing sinks, they tend to suppress formation of secondary aerosol components and enhance formation of ozone. In the cases that unidentified primary emitted species are assumed to account for unidentified missing sinks, a variety of impacts may be observed, which could serve as precursors of secondary organic aerosols (SOA) and significantly increase SOA formation. Missing sinks are considered to play an important role in the atmosphere over Tokyo metropolitan area

The Irrationality of Digital Medicine: VR, IoT and AI in Practice

Artificial Intelligence (AI) has potential to change the tasks that are currently being done by Human being. The Internet of Things (IoT) has potential to increase Medical Device connectivity, enabling more immediate information sharing and coordination between doctors and patients. Virtual reality (VR) has potential to enhance medical training. Digital Health technologies have the power to expand coverage of healthcare (access), enhance services (quality) and reduce/optimize resources (cost). Affordability, infrastructure, and human capability limits overall impacts of Digital Health technologies and must be addressed. Therefore, capacity building through strategic alliances and partnerships remains crucial in harnessing the promises of Digital Health Technologies. This paper summaries challenges in the implementation of Digital health Solutions among African health systems and enumerate the possible ways of addressing the identified challenges. Keywords— Artificial Intelligence (AI), Internet of Things (IoT), Virtual Reality (VR) Digital Health, Remote Patient Monitoring RPM), Robotic Process Automation (RPA