Intrinsic linking and knotting of graphs in arbitrary 3-manifolds

We prove that a graph is intrinsically linked in an arbitrary 3-manifold M if and only if it is intrinsically linked in S^3. Also, assuming the Poincare Conjecture, we prove that a graph is intrinsically knotted in M if and only if it is intrinsically knotted in S^3.Comment: This is the version published by Algebraic & Geometric Topology on 9 August 200

A Case of Multiple Myeloma with Hepatocellular Carcinoma

We report here a 74-year-old man with multiple myeloma (MM) in combination with hepatocellular carcinoma (HCC). Recently, the incidence of MM in combination with another type of cancer has been increasing in Japan. It doubled from 590 in 1978-79 to 1090 between 1985-1989. Among such double cancers, the number of cases of MM combined with HCC has also increased. Although, loss of immunity due to the existence of MM or to anti-cancer drug therapy might cause such a combination, the relationship between immunity and the hepatitis virus as an important cause of HCC is unclear. Attention should be paid to MM as the possible cause of double cancers including HCC