2,300 research outputs found

    Research on the optimal path algorithm in multi-level road network

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    2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Spatial heterogeneity and driving forces of environmental productivity growth in China: Would it help to switch pollutant discharge fees to environmental taxes?

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    © 2019 Elsevier Ltd Emission charge policy has recently switched from pollutant discharge fees to environmental taxes in China. Considering spatial heterogeneity, the effects of changes in emission charge policy may subject to different Chinese regions. In this study, environmental efficiencies of Chinese regions are evaluated through provincial environmentally extended input-output tables and a frontier-based optimization model. Driving factors of environmental productivity growth are identified through global Luenberger productivity decomposition approach. Moreover, spatial heterogeneity on the effects of change in emission charge policy on environment and economy are assessed. Results show that all regions experienced environmental productivity growth. Technology progress is the major driving factor in most regions with an average contribution of 90%, while technical efficiency regress slows environmental productivity growth in Southwest region. Switching from pollutant discharge fees to environmental taxes would decreases emission intensities by 1.42% on average, but it would have different negative impact on economic growth (−1.13%∼-4.90% of regional GDP) due to spatially heterogeneous trade-offs between environmental protection and economic development. Addressing such spatial heterogeneity provide not only a basis for diversified tax rate determination but also a framework for other environmental policy assessment

    Carbon emissions intensity reduction target for China's power industry: An efficiency and productivity perspective

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    © 2018 Elsevier Ltd This paper proposes a scenario analysis to address whether the national and provincial CO2 emissions intensity reduction target during 2016–2020 would be achievable for China's power industry with the identification of change on carbon productivity. This productivity indicator is further decomposed to investigate contributions of different sources to productivity growth when there exists technological heterogeneity. Evaluation results show that even if all electricity-generating units in each region were able to adopt the best practice, the nationwide 18% intensity reduction target is not feasible through improving technical efficiency or upgrading technology on electricity generation and carbon abatement in a short or medium term. The existence of regional technological heterogeneity in power generation and associated CO2 emissions reduction processes implies the necessity of more differentiated regulations and policies for emission reduction across China's regions and inter-regional technology transfer. The emerging national emission trading scheme could easy some challenges in formulating emission policy for heterogeneous regions

    多尺度道路网的距离匹配算法研究

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    Author name used in this publication: SHI Wen-zhongAuthor name used in this publication: 陈玉敏Author name used in this publication: 龚健雅2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Effects of annealing temperature on the characteristics of Ga-doped ZnO film metal-semiconductor-metal ultraviolet photodetectors

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    Compact Broadband Terahertz Perfect Absorber Based on Multi-Interference and Diffraction Effects

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    This is the author accepted manuscript. The final version is available from Institute of Electrical and Electronics Engineers via the DOI in this record.High absorption over a wide frequency band has attracted considerable interest due to its potential applications in imaging and anti-radar cloaking devices. In order to make these devices more integrated, the thickness of the absorber is crucial. In this paper, a compact, polarization-independent, broadband, omnidirectional terahertz (THz) absorber is proposed, fabricated, and evaluated. This THz absorber is based on the combined effect of the multi-interference and diffraction. It is experimentally demonstrated that over 95% absorption can be obtained in the frequency range from 0.75 to 2.41 THz. This well-designed thinner absorber not only reduces the device thickness to 120 μm, but also introduces more interference peaks so that the absorption spectrum is significantly enlarged. Five successive absorption peaks at 0.88, 1.20, 1.53, 1.96, and 2.23 THz are combined into a broadband THz absorption spectrum

    Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.

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    Tight binding of Gdown1 represses RNA polymerase II (Pol II) function in a manner that is reversed by Mediator, but the structural basis of these processes is unclear. Although Gdown1 is intrinsically disordered, its Pol II interacting domains were localized and shown to occlude transcription factor IIF (TFIIF) and transcription factor IIB (TFIIB) binding by perfect positioning on their Pol II interaction sites. Robust binding of Gdown1 to Pol II is established by cooperative interactions of a strong Pol II binding region and two weaker binding modulatory regions, thus providing a mechanism both for tight Pol II binding and transcription inhibition and for its reversal. In support of a physiological function for Gdown1 in transcription repression, Gdown1 co-localizes with Pol II in transcriptionally silent nuclei of early Drosophila embryos but re-localizes to the cytoplasm during zygotic genome activation. Our study reveals a self-inactivation through Gdown1 binding as a unique mode of repression in Pol II function

    Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity.

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    The antimalarial artemisinin (ART) possesses anticancer activity, but its underlying mechanism remains largely unclear. Using a chemical proteomics approach with artemisinin-based activity probes, we identified over 300 specific ART targets. This reveals an anticancer mechanism whereby ART promiscuously targets multiple critical biological pathways and leads to cancer cell death. The specific cytotoxicity of ART against colorectal cancer (CRC) cells rather than normal colon epithelial cells is due to the elevated capacity of heme synthesis in the cancer cells. Guided by this mechanism, the specific cytotoxicity of ART toward CRC cells can be dramatically enhanced with the addition of aminolevulinic acid (ALA), a clinically used heme synthesis precursor, to increase heme levels. Importantly, this novel ART/ALA combination therapy proves to be more effective than an ART monotherapy in a mouse xenograft CRC model. Thus, ART can be repurposed and potentiated by exploitation of its mechanism of action and the metabolic features of the CRC cells
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