845 research outputs found

    Adaptive intelligence applied to numerical optimisation

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    The article presents modification strategies theoretical comparison and experimental results achieved by adaptive heuristics applied to numerical optimisation of several non-constraint test functions. The aims of the study are to identify and compare how adaptive search heuristics behave within heterogeneous search space without retuning of the search parameters. The achieved results are summarised and analysed, which could be used for comparison to other methods and further investigation

    Growth of High Quality ZnMgO Films on Diamond Substrates

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    AbstractZnMgO films were prepared at room temperature on freestanding diamond (FSD) substrates by co-sputtering. The Mg content was controlled by varying RF sputtering power of MgO and the effects of Mg contents on the properties of ZnMgO films were investigated. The results showed that the (0002) peak of ZnMgO shifted from 34.5° to 35.6° with the increasing sputtering power of MgO target. The UV-visible and PL spetra of ZnMgO films revealed that the bandgap of ZnMgO was approximately linear related to the sputtering power of MgO target

    Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies.

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    Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology. Pre-clinical (animal) studies are indispensable for this development. Often, animal infection outcomes bear little relation to human clinical outcome. Here, we review conclusions from pathogen-inoculum dose-finding pilot studies for evaluation of novel infection-control strategies in murine models. Pathogen-inoculum doses are generally preferred that produce the largest differences in quantitative infection outcome parameters between a control and an experimental group, without death or termination of animals due to having reached an inhumane end-point during the study. However, animal death may represent a better end-point for evaluation than large differences in outcome parameters or number of days over which infection persists. The clinical relevance of lower pre-clinical outcomes, such as bioluminescence, colony forming units (CFUs) retrieved or more rapid clearance of infection is unknown, as most animals cure infection without intervention, depending on pathogen-species and pathogen-inoculum dose administered. In human clinical practice, patients suffering from infection present to hospital emergency wards, frequently in life-threatening conditions. Animal infection-models should therefore use prevention of death and recurrence of infection as primary efficacy targets to be addressed by novel strategies. To compensate for increased animal morbidity and mortality, animal experiments should solely be conducted for pre-clinical proof of principle and safety. With the advent of sophisticated in vitro models, we advocate limiting use of animal models when exploring pathogenesis or infection mechanisms

    Time-reversal symmetry breaking in the noncentrosymmetric Zr3Ir superconductor

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    We report the discovery of Zr3Ir as a structurally different type of unconventional noncentrosymmetric superconductor (with Tc=2.3 K), here investigated mostly via muon-spin rotation/relaxation (ÎŒSR) techniques. Its superconductivity was characterized using magnetic susceptibility, electrical resistivity, and heat capacity measurements. The low-temperature superfluid density, determined via transverse-field ÎŒSR and electronic specific heat, suggests a fully gapped superconducting state. The spontaneous magnetic fields, revealed by zero-field ÎŒSR below Tc, indicate the breaking of time-reversal symmetry in Zr3Ir and hence the unconventional nature of its superconductivity. By using symmetry arguments and electronic-structure calculations we obtain a superconducting order parameter that is fully compatible with the experimental observations. Hence, our results clearly suggest that Zr3Ir represents a structurally different member of noncentrosymmetric superconductors with broken time-reversal symmetry

    Quantum algebra in the mixed light pseudoscalar meson states

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    In this paper, we investigate the entanglement degrees of pseudoscalar meson states via quantum algebra Y(su(3)). By making use of transition effect of generators J of Y(su(3)), we construct various transition operators in terms of J of Y(su(3)), and act them on eta-pion-eta mixing meson state. The entanglement degrees of both the initial state and final state are calculated with the help of entropy theory. The diagrams of entanglement degrees are presented. Our result shows that a state with desired entanglement degree can be achieved by acting proper chosen transition operator on an initial state. This sheds new light on the connect among quantum information, particle physics and Yangian algebra.Comment: 9 pages, 3 figure

    Phase separation and ferroelectric ordering in charge frustrated LuFe2O4-x

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    The transmission electron microscopy observations of the charge ordering (CO) which governs the electronic polarization in LuFe2O4-x clearly show the presence of a remarkable phase separation at low temperatures. Two CO ground states are found to adopt the charge modulations of Q1 = (1/3, 1/3, 0) and Q2 = (1/3 + y, 1/3 + y, 3/2), respectively. Our structural study demonstrates that the incommensurately Q2-modulated state is chiefly stable in samples with relatively lower oxygen contents. Data from theoretical simulations of the diffraction suggest that both Q1- and Q2-modulated phases have ferroelectric ordering. The effects of oxygen concentration on the phase separation and electric polarization in this layered system are discussed.Comment: 11 pages, 5 figure

    Quantifying atmospheric nitrogen deposition through a nationwide monitoring network across China

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    A Nationwide Nitrogen Deposition Monitoring Network (NNDMN) containing 43 monitoring sites was established in China to measure gaseous NH3, NO2, and HNO3 and particulate NH4+ and NO3− in air and/or precipitation from 2010 to 2014. Wet/bulk deposition fluxes of Nr species were collected by precipitation gauge method and measured by continuous-flow analyzer; dry deposition fluxes were estimated using airborne concentration measurements and inferential models. Our observations reveal large spatial variations of atmospheric Nr concentrations and dry and wet/bulk Nr deposition. On a national basis, the annual average concentrations (1.3–47.0 ÎŒg N m−3) and dry plus wet/bulk deposition fluxes (2.9–83.3 kg N ha−1 yr−1) of inorganic Nr species are ranked by land use as urban > rural > background sites and by regions as north China > southeast China > southwest China > northeast China > northwest China > Tibetan Plateau, reflecting the impact of anthropogenic Nr emission. Average dry and wet/bulk N deposition fluxes were 20.6 ± 11.2 (mean ± standard deviation) and 19.3 ± 9.2 kg N ha−1 yr−1 across China, with reduced N deposition dominating both dry and wet/bulk deposition. Our results suggest atmospheric dry N deposition is equally important to wet/bulk N deposition at the national scale. Therefore, both deposition forms should be included when considering the impacts of N deposition on environment and ecosystem health

    Evolution and Flare Activity of Delta-Sunspots in Cycle 23

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    The emergence and magnetic evolution of solar active regions (ARs) of beta-gamma-delta type, which are known to be highly flare-productive, were studied with the SOHO/MDI data in Cycle 23. We selected 31 ARs that can be observed from their birth phase, as unbiased samples for our study. From the analysis of the magnetic topology (twist and writhe), we obtained the following results. i) Emerging beta-gamma-delta ARs can be classified into three topological types as "quasi-beta", "writhed" and "top-to-top". ii) Among them, the "writhed" and "top-to-top" types tend to show high flare activity. iii) As the signs of twist and writhe agree with each other in most cases of the "writhed" type (12 cases out of 13), we propose a magnetic model in which the emerging flux regions in a beta-gamma-delta AR are not separated but united as a single structure below the solar surface. iv) Almost all the "writhed"-type ARs have downward knotted structures in the mid portion of the magnetic flux tube. This, we believe, is the essential property of beta-gamma-delta ARs. v) The flare activity of beta-gamma-delta ARs is highly correlated not only with the sunspot area but also with the magnetic complexity. vi) We suggest that there is a possible scaling-law between the flare index and the maximum umbral area
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