17 research outputs found

    From Poverty to Economic Independence: An Examination of Factors Contributing to Success and Self-Sufficiency among Black Male Family Self-Sufficiency Program Participants

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    The purpose of this study was to acquire accurate information concerning the motivations and methods utilized by Black males who have successfully achieved economic independence, as well as the ways in which they maintain their economic independence. The scope of this study was to examine adult Black males who had successfully completed a Family Self-Sufficiency program and are currently economically independent. Using a phenomenological methodology, their experiences and a description of the relationship connecting the problem statement, research question, theory and study design was completed. This study revealed perceptions that were contrary to popular mainstream beliefs about impoverished Black males. Family and an intrinsic motivation to succeed were echoed by the participants as the driver that leads them to economic independence. This study found three major implications; the first implication was participants expressed a belief that discrimination is a legitimate problem which can hinder one’s opportunities for employment and upward mobility. The second implication was that participants believe they are viewed as threatening and dangerous, especially to law enforcement. The last implication of this study was that the participants were conservative in their ideological perspective. Though their political affiliation was Democrat, ideologically their views were fundamentally conservative. Most importantly, these participants did not allow societal hindrance to deter them from their ultimate goal of economic independence for themselves as well as their families

    Array programming with NumPy.

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    Array programming provides a powerful, compact and expressive syntax for accessing, manipulating and operating on data in vectors, matrices and higher-dimensional arrays. NumPy is the primary array programming library for the Python language. It has an essential role in research analysis pipelines in fields as diverse as physics, chemistry, astronomy, geoscience, biology, psychology, materials science, engineering, finance and economics. For example, in astronomy, NumPy was an important part of the software stack used in the discovery of gravitational waves1 and in the first imaging of a black hole2. Here we review how a few fundamental array concepts lead to a simple and powerful programming paradigm for organizing, exploring and analysing scientific data. NumPy is the foundation upon which the scientific Python ecosystem is constructed. It is so pervasive that several projects, targeting audiences with specialized needs, have developed their own NumPy-like interfaces and array objects. Owing to its central position in the ecosystem, NumPy increasingly acts as an interoperability layer between such array computation libraries and, together with its application programming interface (API), provides a flexible framework to support the next decade of scientific and industrial analysis

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    From Poverty to Economic Independence: An Examination of Factors Contributing to Success and Self-Sufficiency among Black Male Family Self-Sufficiency Program Participants

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    The purpose of this study was to acquire accurate information concerning the motivations and methods utilized by Black males who have successfully achieved economic independence, as well as the ways in which they maintain their economic independence. The scope of this study was to examine adult Black males who had successfully completed a Family Self-Sufficiency program and are currently economically independent. Using a phenomenological methodology, their experiences and a description of the relationship connecting the problem statement, research question, theory and study design was completed. This study revealed perceptions that were contrary to popular mainstream beliefs about impoverished Black males. Family and an intrinsic motivation to succeed were echoed by the participants as the driver that leads them to economic independence. This study found three major implications; the first implication was participants expressed a belief that discrimination is a legitimate problem which can hinder one’s opportunities for employment and upward mobility. The second implication was that participants believe they are viewed as threatening and dangerous, especially to law enforcement. The last implication of this study was that the participants were conservative in their ideological perspective. Though their political affiliation was Democrat, ideologically their views were fundamentally conservative. Most importantly, these participants did not allow societal hindrance to deter them from their ultimate goal of economic independence for themselves as well as their families

    From Poverty to Economic Independence: An Examination of Factors Contributing to Success and Self-Sufficiency among Black Male Family Self-Sufficiency Program Participants

    No full text
    The purpose of this study was to acquire accurate information concerning the motivations and methods utilized by Black males who have successfully achieved economic independence, as well as the ways in which they maintain their economic independence. The scope of this study was to examine adult Black males who had successfully completed a Family Self-Sufficiency program and are currently economically independent. Using a phenomenological methodology, their experiences and a description of the relationship connecting the problem statement, research question, theory and study design was completed. This study revealed perceptions that were contrary to popular mainstream beliefs about impoverished Black males. Family and an intrinsic motivation to succeed were echoed by the participants as the driver that leads them to economic independence. This study found three major implications; the first implication was participants expressed a belief that discrimination is a legitimate problem which can hinder one’s opportunities for employment and upward mobility. The second implication was that participants believe they are viewed as threatening and dangerous, especially to law enforcement. The last implication of this study was that the participants were conservative in their ideological perspective. Though their political affiliation was Democrat, ideologically their views were fundamentally conservative. Most importantly, these participants did not allow societal hindrance to deter them from their ultimate goal of economic independence for themselves as well as their families

    Chimeric Human Immunodeficiency Virus Type 1 Containing Murine Leukemia Virus Matrix Assembles in Murine Cells

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    Murine cells do not support efficient assembly and release of human immunodeficiency virus type 1 (HIV-1) virions. HIV-1-infected mouse cells that express transfected human cyclin T1 synthesize abundant Gag precursor polyprotein, but inefficiently assemble and release virions. This assembly defect may result from a failure of the Gag polyprotein precursor to target to the cell membrane. Plasma membrane targeting of the precursor is mediated by the amino-terminal region of polyprotein. To compensate for the assembly block, we substituted the murine leukemia virus matrix coding sequences into an infectious HIV-1 clone. Transfection of murine fibroblasts expressing cyclin T1 with the chimeric proviruses resulted in viruses that were efficiently assembled and released. Chimeric viruses, in which the cytoplasmic tail of the transmembrane subunit, gp41, was truncated to prevent potential interference between the envelope glycoprotein and the heterologous matrix, could infect human and murine cells. They failed to further replicate in the murine cells, but replicated with delayed kinetics in human MT-4 cells. These findings may be useful for establishing a murine model for HIV-1 replication

    pydata/patsy: v0.5.6

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    <p>This is a minor release pre-empting some upstream deprecations in <code>numpy</code> and <code>pandas</code>.</p> <ul> <li>Avoid using deprecated <code>is_categorical_dtype</code> from <code>pandas</code> at all in pandas >=0.25. (thanks @EpigeneMax, @lesteve, @bashtage)</li> <li>Avoid using deprecated <code>numpy.row_stack</code> in favor of <code>numpy.vstack</code> in preparation from numpy 2.0. (thanks @bashtage)</li> </ul&gt
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