5,478 research outputs found
The Neumann Problem and Helmholtz Decomposition in Convex Domains
We show that the Neumann problem for Laplace's equation in a convex domain
with boundary data in is uniquely solvable for
. As a consequence, we obtain the Helmholtz decomposition of vector
fields in .Comment: 17 page
Uniform W^{1,p} Estimates for Systems of Linear Elasticity in a Periodic Medium
Let be a family of elliptic systems of linear
elasticity with rapidly oscillating periodic coefficients. We obtain the
uniform estimate in a Lipschitz domain for solutions to the Dirichlet
problem, where . The ranges of 's
are sharp for or 3
INVESTIGATION OF THE TOXICITY AND EFFLUX OF POLYCHLORINATED BIPHENYLS AND HYDROXYLATED POLYCHLORINATED BIPHENYLS IN \u3cem\u3eESCHERICHIA COLI\u3c/em\u3e
Polychlorinated biphenyls (PCBs) are persistent organic pollutants. Due to their properties, PCBs accumulate in the food-chain and post a threat to the health of human beings and wildlife. Hydroxylated PCBs (OH-PCBs) are oxidative metabolites of PCBs and are more hydrophilic than their parent PCBs. One of the best approaches to break down these contaminants is through bioremediation, which is an environmental friendly process that uses microorganisms to restore natural environment.
Towards this goal, we have investigated the toxicity and accumulation of PCBs and OH-PCBs in a Gram-negative bacterium, Escherichia coli. We have also determined the role played by a primary multidrug efflux transporter AcrB on the accumulation of PCBs and OH-PCBs in bacterial cell. We found that one of the PCBs tested was toxic to E. coli, while different OH-PCBs have different levels of toxicity; the acrB knockout strain accumulated significantly more PCBs and OH-PCBs than the wild-type strain, suggesting that these compounds are substrates of the efflux pump; higher cytoplasmic concentrations of OH-PCBs were also observed in the acrB knockout strain using the biosensors. Based on these observations, we conclude that both PCBs and OH-PCBs are substrates of protein AcrB. Therefore the efflux activities of multidrug resistant pumps in Gram-negative bacteria should be considered while designing bioremediation approaches
Matter Power Spectra in Viable Gravity Models with Massive Neutrinos
We investigate the matter power spectra in the power law and exponential
types of viable theories along with massive neutrinos. The enhancement
of the matter power spectrum is found to be a generic feature in these models.
In particular, we show that in the former type, such as the Starobinsky model,
the spectrum is magnified much larger than the latter one, such as the
exponential model. A greater scale of the total neutrino mass, , is allowed in the viable models than that in the CDM
one. We obtain the constraints on the neutrino masses by using the CosmoMC
package with the modified MGCAMB. Explicitly, we get $\Sigma m_{\nu} < 0.451 \
(0.214)\ \mathrm{eV}\Lambda\Sigma m_{\nu} < 0.200\
\mathrm{eV}N_{\mathrm{eff}}\Sigma m_{\nu}N_{\mathrm{eff}} = 3.78^{+0.64}_{-0.84} (3.47^{+0.74}_{-0.60})\Sigma m_{\nu} = 0.533^{+0.254}_{-0.411}< 0.386) \ \mathrm{eV}$ at 95%
C.L. in the Starobinsky (exponential) model.Comment: 15 pages, 5 figures, updated version accepted by PL
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