Romantic involvement and adolescents' academic and psychosocial functioning in Chinese societies

© 2018 This study explores the effects of romantic involvement and dating behaviors on adolescent academic and psychosocial functioning in Chinese societies, where adolescent dating is generally discouraged and believed to generate adverse outcomes. Adolescents (male = 48.6%; MeanAge = 15.20 years) from Taiwan (N = 1081) and mainland China (N = 684) were recruited through stratified sampling to complete self-report surveys on their academic performance, depressive symptoms, self-esteem, relationship status, and gender-role beliefs. Adolescents with current or past dating experiences were also asked about specific dating behaviors, such as the onset of dating, number of relationships, and breakup experiences. Approximately one-third of Chinese adolescents surveyed (34.2%) have past or ongoing dating experience, who showed poorer academic performance compared to never-dated teens. In the full sample, single adolescents with past dating experiences reported greater depressive symptoms than those currently dating or never-dated teens. Boys with past dating experience showed higher self-esteem than their currently dating or never-dated peers, whereas single girls with past dating experience showed lower self-esteem than their currently dating or never-dated counterparts. Among adolescents with dating experience, early dating, over-dating, sexual activities, and breakup experiences can undermine their academic and psychosocial well-being. These findings have significant implications for practice and policy regarding adolescent education and mental health

Integrin-mediated membrane blebbing is dependent on the NHE1 and NCX1 activities.

Integrin-mediated signal transduction and membrane blebbing have been well studied to modulate cell adhesion, spreading and migration^1-6^. However, the relationship between membrane blebbing and integrin signaling has not been explored. Here we show that integrin-ligand interaction induces membrane blebbing and membrane permeability change. We found that sodium-proton exchanger 1 (NHE1) and sodium-calcium exchanger 1 (NCX1) are located in the membrane blebbing sites and inhibition of NHE1 disrupts membrane blebbing and decreases membrane permeability change. However, inhibition of NCX1 enhances cell blebbing to cause cell swelling which is correlated with an intracellular sodium accumulation induced by NHE17. These data suggest that sodium influx induced by NHE1 is a driving force for membrane blebbing growth, while sodium efflux induced by NCX1 in a reverse mode causes membrane blebbing retraction. Together, these data reveal a novel function of NHE1 and NCX1 in membrane permeability change and blebbing and provide the link for integrin signaling and membrane blebbing

On the Impossibility of General Parallel Fast-Forwarding of Hamiltonian Simulation

Hamiltonian simulation is one of the most important problems in the field of quantum computing. There have been extended efforts on designing algorithms for faster simulation, and the evolution time T for the simulation greatly affect algorithm runtime as expected. While there are some specific types of Hamiltonians that can be fast-forwarded, i.e., simulated within time o(T), for some large classes of Hamiltonians (e.g., all local/sparse Hamiltonians), existing simulation algorithms require running time at least linear in the evolution time T. On the other hand, while there exist lower bounds of ?(T) circuit size for some large classes of Hamiltonian, these lower bounds do not rule out the possibilities of Hamiltonian simulation with large but "low-depth" circuits by running things in parallel. As a result, physical systems with system size scaling with T can potentially do a fast-forwarding simulation. Therefore, it is intriguing whether we can achieve fast Hamiltonian simulation with the power of parallelism. In this work, we give a negative result for the above open problem in various settings. In the oracle model, we prove that there are time-independent sparse Hamiltonians that cannot be simulated via an oracle circuit of depth o(T). In the plain model, relying on the random oracle heuristic, we show that there exist time-independent local Hamiltonians and time-dependent geometrically local Hamiltonians on n qubits that cannot be simulated via an oracle circuit of depth o(T/n^c), where the Hamiltonians act on n qubits, and c is a constant. Lastly, we generalize the above results and show that any simulators that are geometrically local Hamiltonians cannot do the simulation much faster than parallel quantum algorithms

Childhood tuberculosis in southern Taiwan, with emphasis on central nervous system complications

Background/PurposeChildhood tuberculosis (TB) continues to be a major public health problem in Taiwan. Taiwan remains a highly endemic area despite neonatal Bacillus Calmette–Guérin (BCG) vaccination and the availability of anti-TB therapy. The presentation is highly variable and it is often difficult to make an accurate diagnosis. This study was designed to evaluate the demographic, clinical, and laboratory findings and outcomes of TB in children with emphasis on central nervous system (CNS) complications.MethodsThe medical records of 80 children diagnosed with TB at a medical center in southern Taiwan over the past 24 years (1988–2012) were reviewed.ResultsAmong them, 48.8% (39/80) had pulmonary TB, 27.5% (22/80) had isolated extrapulmonary TB, and 23.7% (19/80) had disseminated TB. Most infected cases were aged either < 4 years or > 12 years. TB contact history was found in 42.5% (34/80) cases. Fourteen (17.5%) of the cases had CNS involvement. The most common presentations were fever (85.7%), signs of increased intracranial pressure (71.4%), drowsiness (64.3%), and focal neurological signs (57.1%). The major radiological findings were tuberculoma (50%), basilar enhancement (41.6%), infarction (41.6%), hydrocephalus (16.6%), and transverse myelitis (16.6%). The case fatality of CNS TB was 14.3% and 21.4% had neurologic sequelae.ConclusionFindings suggest that positive exposure history and suspicious clinical presentations are important clues for further confirmatory laboratory and image studies in childhood TB. CNS TB usually presented as part of disseminated TB in children. Early diagnosis and treatment may lead to favorable outcomes in CNS TB

Cultural Perspective on Parenting, Trait Emotional Intelligence and Mental Health in Taiwanese Children

The current study aims to clarify the associations as well as the pathways through which parenting and children's emotional intelligence (EI) may influence children's mental health with a cross-sectional sample of 675 school pupils (fourth grade, mean age = 10.4 years, 310 boy, 356 girls and 9 unidentified) in Taiwan. Hierarchical regression and path analyses were used to examine the relationships between parenting styles, children's trait EI, and their psychological symptoms, with children's psychological symptoms as the dependent variable. The results showed that authoritative parenting was positively associated with children‟s trait EI, which in turn had a negative effect on children‟s psychological symptoms, whereas authoritarian and Chinese-specific parenting styles had direct negative effect on children‟s psychological symptoms. These findings shed light on the pathways of the interrelations between different parenting styles, children's trait EI, and psychological symptoms, providing theoretical as well as practical implications for children's emotional development and mental health

Effects of Electroacupuncture on Benign Prostate Hyperplasia Patients with Lower Urinary Tract Symptoms: A Single-Blinded, Randomized Controlled Trial

We tested the effect of electroacupuncture (EA) on lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH) patients. A total of 42 BPH patients with LUTS were randomly assigned to either the EA group (EG), received 2 Hz EA for 20 min twice/week for a total of twelve treatments, or a sham EA group (CG), received sham EA. The increase of voiding volume, average flow rate, and maximal flow rate in the EG were 32.2 ± 104.4 mL, 1.2 ± 1.6 mL/sec, and 2.3 ± 3.7 mL/sec, respectively, from baseline value (before EA) using the measurement of an uroflowmetry. These increases were greater than −37.9 ± 120.4, −0.22 ± 2.7, and −0.3 ± 4.3, respectively, in the CG (P = .038, .026, and .030, resp.). The changes of prostate special antigen and international prostatic symptom score were not significantly different between two groups (P = .573, .175, resp.), suggesting the clinical improvement of 2 Hz EA was quite limited to the LUTS of patients with BPH