20 research outputs found
Significant reduction of peripheral blood interleukin-35 and CD4+EBI3+ T cells, which are negatively correlated with an increase in the plasma IL-17 and cTnI level, in viral myocarditis patients
Tunable van Hove singularity without structural instability in Kagome metal CsTiBi
In Kagome metal CsVSb, multiple intertwined orders are accompanied by
both electronic and structural instabilities. These exotic orders have
attracted much recent attention, but their origins remain elusive. The newly
discovered CsTiBi is a Ti-based Kagome metal to parallel CsVSb.
Here, we report angle-resolved photoemission experiments and first-principles
calculations on pristine and Cs-doped CsTiBi samples. Our results
reveal that the van Hove singularity (vHS) in CsTiBi can be tuned in a
large energy range without structural instability, different from that in
CsVSb. As such, CsTiBi provides a complementary platform to
disentangle and investigate the electronic instability with a tunable vHS in
Kagome metals
Significant reduction of peripheral blood interleukin-35 and CD4+EBI3+ T cells, which are negatively correlated with an increase in the plasma IL-17 and cTnI level, in viral myocarditis patients
Introduction: Viral myocarditis (VMC) has become an increasingly common heart disease that endangers human health. In the present study, the plasma interleukin-35 (IL-35) level and the percentage of CD4 + EBI3 + T cells in VMC patients were detected to investigate the significance of changes in these parameters in the plasma of VMC patients and their association with the disease.
Material and methods: ELISA was performed to detect the plasma IL-35 level and the percentage of peripheral blood CD4 + EBI3 + T cells in 40 VMC patients and in 20 healthy individuals. Moreover, the plasma IL-17 levels in the VMC patients and in the healthy individuals were detected using an ELISA, and the cardiac Troponin-I (cTnI) levels were detected using a chemiluminescent microparticle immunoassay to compare the differences in the groups.
Results : Plasma IL-35 level and the percentage of CD4 + EBI3 + T cells in acute phase VMC patients was lower than that in the healthy control group and the convalescent phase VMC patients. Additionally, the plasma IL-35 level in the VMC patients exhibited a negative correlation with the levels of cTnI and IL-17. The percentage of CD4 + EBI3 + T cells also showed a negative correlation with the levels of cTnI and IL-17.
Conclusions : The plasma IL-35 level and the percentage of CD4 + EBI3 + T cells in VMC patients was reduced, and the amount of the decrease was associated with the severity of the disease. These results suggest that IL-35 and CD4 + EBI3 + T might play important roles in the progression of VMC and could be used as indictors of the disease
The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia
Addition of Ixazomib to an Rd Backbone Improves Clinical Benefit in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (Pts) with Non-Canonical NF-KB Activation — Results from the Tourmaline-MM1 Study
Magnetic solid-phase extraction and determination of puerarin in rat plasma using C18-functionalized magnetic silica nanoparticles by high performance liquid chromatography
SAFFLOWER SEED-DERIVED DES-1,2-APOA1MILANO REDUCES ATHEROSCLEROSIS IN HYPERCHOLESTEROLEMIC APOLIPOPROTEIN E (-/-) MICE
Evaluating the impacts of soil data on hydrological and nonpoint source pollution prediction
Two-dimensional phase diagram of the charge density wave in doped CsV3Sb5
Abstract Kagome superconductors AV3Sb5 (A = K, Rb and Cs) have attracted much recent attention due to the coexistence of multiple exotic orders. Among them, the charge density wave (CDW) order has been shown to host various unconventional behaviors. Here, we investigate the CDW order by a combination of both bulk and surface doping methods. While element substitutions in bulk doping change both carriers and the crystal lattice, the surface doping primarily tunes the carrier concentration. As such, our results reveal a two-dimensional phase diagram of the CDW in doped CsV3Sb5. In the lightly bulk doped regime, the existence of CDW order is reversible by tuning the carrier concentration. But excessive bulk doping permanently destroys the CDW, regardless of the carrier doping level. These results provide insights to the origin of the CDW from both electronic and structural degrees of freedom. They also open an avenue for manipulating the exotic CDW order in Kagome superconductors