The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

The Evaluation of the Awareness, Attitude and Practice of the Elderly Toward Self-Medication: A Cross-Sectional Study.

Abstract INTRODUCTION: The prevalence of various diseases in the elderly has increased the use of drugs, which is coupled with age-related physiological changes and places the elderly at risk for multiple side effects. The present study aimed to determine awareness, attitudes and practices of elderly towards self-medication. MATERIALS AND METHODS: The sample included 300 participants over 60 years under any of the health centers in urban and rural areas of Abadeh city, who were selected based on stratified random sampling method. In order to collect data, the questionnaire including demographic information, awareness, attitude and performance of the elderly and the checklist of drug intractable consumption. RESULTS: Based on the results, 76% of the elderly reported drug consumption. Regarding lifestyle, the average score of the elderly's awareness for the elderly who lived with and without families were 78.6±14.2 and 69.2±13.6, respectively. In other words, a significant difference was observed between these two groups. In addition, there was a significant between the elderly's performance score with and without family members about the self-medication (p=0.001). CONCLUSION: Considering the increase in self-medication among the elderly, adherence to prescription criteria for drug among this age group is recommended. Finally, designing and implementing various educational programs in health education center is necessary for the elderly and their families for the purpose of improving awareness and practice

The Evaluation of the Awareness, Attitude and Practice of the Elderly Toward Self-Medication: A Cross-Sectional Study

Introduction The prevalence of various diseases in the elderly has increased the use of drugs, which is coupled with age-related physiological changes and places the elderly at risk for multiple side effects. The present study aimed to determine awareness, attitudes and practices of elderly towards self-medication. Materials and Methods The sample included 300 participants over 60 years under any of the health centers in urban and rural areas of Abadeh city, who were selected based on stratified random sampling method. In order to collect data, the questionnaire including demographic information, awareness, attitude and performance of the elderly and the checklist of drug intractable consumption. Results Based on the results, 76 of the elderly reported drug consumption. Regarding lifestyle, the average score of the elderly's awareness for the elderly who lived with and without families were 78.6±14.2 and 69.2±13.6, respectively. In other words, a significant difference was observed between these two groups. In addition, there was a significant between the elderly's performance score with and without family members about the self-medication (p=0.001). Conclusion Considering the increase in self-medication among the elderly, adherence to prescription criteria for drug among this age group is recommended. Finally, designing and implementing various educational programs in health education center is necessary for the elderly and their families for the purpose of improving awareness and practice. © 2018 Georg Thieme Verlag. All rights reserved

Role of Religious Institutions in Disaster Risk Management: A Systematic Review

Objectives: The aim of this systematic review is to analyze the relevant research on religious organizations' participation in disasters risk management and to understand the ways in which these organizations impact on disaster management. Today, community-based disaster risk management is emphasized as a very effective approach. Religious organizations are one of the most important components of community. They have access to resources that can be critical to help government agencies to manage disasters successfully. Methods: This systematic review was conducted since August 2018 to investigate the role of religious institutions in disasters management and was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Web of Science (WOS), Scopus, Proquest, Embase, and Google scholar were the primary databases used for search of literature. Keywords used in this review were religious institution, disaster management, and their equivalents were obtained from Mesh, Emtree, or extracted from related articles. The papers from a broad range of disciplines related to keywords were included, and those articles that focus on response to disaster based on religious beliefs' and religion rather than participation of religious institutions in disaster risk management were excluded. From the 18,071 records identified through database searching in the early stage, 22 articles were selected for this review followed by analysis of the characteristics and content analysis of the included studies to answer the study questions. Results: The findings of this systematic review that emerged from content analysis are summarized in 11 themes: religious institutions' potential for disaster management, preparedness of religious institutions for disasters, response, recovery, the social capital, partnership with all stakeholders, collaboration and communication between mental health professionals and faith-based organization leaders, unity of information and message, religious institution shelters, dealing with disaster in old and new approaches, and barriers and challenges. Conclusions: Religious institutions have a vital role and great potential in disasters management. They often contribute in response and recovery phases of disasters, although these services are valuable but the great potential of these groups should also be recruited to participate in preparedness and mitigation efforts as part of disasters cycle. Coordination and collaboration of all stakeholders is essential in this way. Copyright © 2020 Society for Disaster Medicine and Public Health, Inc.