12 research outputs found
Desenvolvimento do sistema tegumentar em bovinos com idades gestacionais estimadas de 20 a 140 dias
Covalent Stabilization Of Coagulation Factor Xa Enhances Its Fibrinolytic Function In Vitro and In Vivo: A Novel Cofactor-Based Thrombolytic Agent
Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1)
Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1)
Frequência de ovinos soropositivos para lentivírus de pequenos ruminantes no município de Colinas do Tocantins, estado do Tocantins, Brasil
Toward Global Drought Early Warning Capability: Expanding International Cooperation for the Development of a Framework for Monitoring and Forecasting
Enzyme Electrophoretic Evidence for Diploidy in Japanese Woodwardia japonica (L.f.) Sm. (Blechnaceae, Pteridophyte) with 2n = 68
Daughter Cell Assembly in the Protozoan Parasite Toxoplasma gondii
The phylum Apicomplexa includes thousands of species of obligate intracellular parasites, many of which are significant human and/or animal pathogens. Parasites in this phylum replicate by assembling daughters within the mother, using a cytoskeletal and membranous scaffolding termed the inner membrane complex. Most apicomplexan parasites, including Plasmodium sp. (which cause malaria), package many daughters within a single mother during mitosis, whereas Toxoplasma gondii typically packages only two. The comparatively simple pattern of T. gondii cell division, combined with its molecular genetic and cell biological accessibility, makes this an ideal system to study parasite cell division. A recombinant fusion between the fluorescent protein reporter YFP and the inner membrane complex protein IMC1 has been exploited to examine daughter scaffold formation in T. gondii. Time-lapse video microscopy permits the entire cell cycle of these parasites to be visualized in vivo. In addition to replication via endodyogeny (packaging two parasites at a time), T. gondii is also capable of forming multiple daughters, suggesting fundamental similarities between cell division in T. gondii and other apicomplexan parasites