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A Note on Using the Nonparametric Levene Test When Population Means Are Unequal
This computer simulation study evaluates the robustness of the nonparametric Levene test of equal variances (Nordstokke & Zumbo, 2010) when sampling from populations with unequal (and unknown) means. Testing for population mean differences when population variances are unknown and possibly unequal is often referred to as the Behrens-Fisher problem when the populations are normally distributed, and the generalized Behrens-Fisher problem when the populations are non-normal. The nonparametric Levene test was developed to overcome reductions in power of the original Levene test of equal variances in the case of the generalized Behrens-Fisher problem. We use a Monte Carlo computer simulation to demonstrate that sampling from populations with unequal and unknown means can lead to incorrect (either inflated or decreased) Type I error rates of the nonparametric Levene test. Centering samples using either sample means or medians does not correct the Type I error rates. This note is intended to make applied researchers aware of this problem when testing for the equality of population variances with the NPL test and in general. Accessed 1,444 times on https://pareonline.net from September 17, 2018 to December 31, 2019. For downloads from January 1, 2020 forward, please click on the PlumX Metrics link to the right
On the evolution of decoys in plant immune systems
The Guard-Guardee model for plant immunity describes how resistance proteins
(guards) in host cells monitor host target proteins (guardees) that are
manipulated by pathogen effector proteins. A recently suggested extension of
this model includes decoys, which are duplicated copies of guardee proteins,
and which have the sole function to attract the effector and, when modified by
the effector, trigger the plant immune response. Here we present a
proof-of-principle model for the functioning of decoys in plant immunity,
quantitatively developing this experimentally-derived concept. Our model links
the basic cellular chemistry to the outcomes of pathogen infection and
resulting fitness costs for the host. In particular, the model allows
identification of conditions under which it is optimal for decoys to act as
triggers for the plant immune response, and of conditions under which it is
optimal for decoys to act as sinks that bind the pathogen effectors but do not
trigger an immune response.Comment: 15 pages, 6 figure
Lateralization and detection of low‐frequency binaural stimuli: Effects of distribution of internal delay
Brief Measure for Screening Complicated Grief: Reliability and Discriminant Validity
BACKGROUND: Complicated grief, which is often under-recognized and under-treated, can lead to substantial impairment in functioning. The Brief Grief Questionnaire (BGQ) is a 5-item self-report or interview instrument for screening complicated grief. Although investigations with help-seeking samples suggest that the BGQ is valid and reliable, it has not been validated in a broader population. METHODOLOGY/PRINCIPAL FINDINGS: A questionnaire was mailed to a randomly selected sample (n = 5000) residing in one of 4 areas of Japan. The BCQ was examined for responders who were bereaved more than 6 months and less than 10 years (n = 915). Non-specific psychological distress was assessed with the K6 screening scale. Multiple group confirmatory factor analysis supported a uni-dimensional factor structure and the invariance of parameters across gender and age. Cronbach's alpha was sufficiently high (alpha = .75) to confirm internal consistency. Average Variance Extracted (0.39) was higher than the shared covariance (0.14) between BGQ and K6, suggesting discriminant validity. CONCLUSIONS: The results of this study support the reliability and validity of the BGQ in the Japanese population. Future studies should examine predictive validity by using structured interviews or more detailed scales for complicated grief
Internal consistency and discriminant validity of the Structured Clinical Interview for Panic Agoraphobic Spectrum (SCI-PAS)
This paper reports on the feasibility, acceptability and psychometric properties of the Structured Clinical Interview for Panic-Agoraphobic Spectrum (SCI-PAS). This interview was designed to assess the lifetime presence of symptoms and other clinical features considered to comprise the panic-agoraphobic spectrum. The interview has 114 items grouped into nine domains. A total of 422 subjects, from 11 centres located throughout Italy, participated in this study. Data were collected from three groups of subjects: psychiatric patients meeting DSM-IV criteria for panic disorder (n = 141), cardiovascular patients (n = 140), including 29 with post-myocardial infarction, and university students (n = 141). The inter-rater reliability and the internal consistency of the SCI-PAS measures were assessed using the intra-class correlation coefficient and the Kuder-Richardson coefficient, respectively. Discriminant validity was assessed by comparing results in patients with panic disorder to those in the other groups. The interview required an average of 25 (±5) minutes to administer. Patients and clinicians found the scale to be highly useful, providing information not previously obtained. Internal consistency was good (>0.70) for six out of nine SCI-PAS domains. The inter-rater reliability was excellent (>0.70) for all the domains except for 'other phobias' (0.467). Patients with panic disorder scored significantly higher on each domain, and on the overall panic spectrum, than did the control subjects. In conclusion, the SCI-PAS is a useful clinical interview, which can be administered in a reasonable period of time. This assessment further demonstrates good internal consistency, discriminant validity, and inter-rater reliability. Copyright © 1999 Whurr Publishers Ltd
Terrestrial arachnids
74 p. : ill. ; 26 cm.Includes bibliographical references (p. 72-74)."Three new genera and seven new species of the arachnid order Trigonotarbida are described based on remarkably well preserved fossils from the late Middle Devonian (Givetian) of Gilboa, New York: Gilboarachne griersoni, Gelasinotarbus reticulatus, G. bonamoae, G. bifidus, G. heptops, G.? fimbriunguis, and Aculeatarbus depressus. A brief review of other known Devonian trigonotarbids is presented, and certain misconceptions about the order are rectified, including the nature of the eyes, chelicerae, claws, and abdominal segmentation. Trigonotarbida is shown by cladistic analysis to be the plesiomorphic sister-group of Araneae + Amblypygi + Uropygi + Schizomida"--P. 2
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