ANALISIS SPILLOVER EFFECT PERTUMBUHAN EKONOMI KABUPATEN/KOTA DI KORIDOR TIMUR PROVINSI JAWA TIMUR TAHUN 1993-2021

The spillover effect is an influence that arises because of the dependency relationship between regions, the influence given is the spread effect and the backwash effect. This study aims to determine the spillover effect of economic growth provided by one region to other regions and determine the causal relationship between economic growth between districts/cities. This research was conducted in the East Java Corridor. The data used is secondary data, namely data taken from the Central Bureau of Statistics (BPS). The data used is PDRB ADHK. The research method used is the VECM model and Granger Causality. The results show that the economic growth of a region to other regions between Regencies/Cities in the East Java Corridor has different effects, namely the spread effect and the backwash effect. The influence of the spread effect is smaller than the backwash effect. The relationship between economic growth between Regencies/Cities in the East Java Corridor is mostly one-way

Uji Daya Hambat terhadap Pertumbuhan Bakteri Uji Staphylococcus aureus dan Escherichia coli Ekstrak Etanol Daun Mangrove Rhizophora mucronata dan Efek Antidiabetiknya pada Mencit yang Diinduksi Aloksan.

Tujuan dari penelitian ini yakni untuk mengetahui komponen senyawa bioaktif , aktivitas anti mikroba dan efek antidiabetik dari daun tanaman Rhizopora mucronata. Sampel berupa daun bakau diproleh dari kawasan pesisir pantai Barru. Daun Rhizopora mucronata diekstraksi dengan cara maserasi menggunakan etanol 96% selama 3 × 24 jam. Ekstrak kemudian diuji secara fitokimia, uji anti mikroba dan uji antidiabetik. Dari hasil uji fitokimia ekstrak daun Rhizopora mucronata positif mengandung gugus fenolik. Sedangkan berdasarkan hasil uji antimikroba terhadap bakteri uji yaitu Staphylococcus aureus dan Escherichia coli, ekstrak daun Rhizopora mucronata menunjukkan tidak adanya aktifitas antimikroba terhadap jenis mikroba yang diujikan. Sedangkan berdasarkan uji antidiabetik ekstrak etanol daun Rhizopora mucronata dapat menurunkan kadar glukosa darah mencit yang mengalami hiperglikemia setelah diinduksi dengan aloksan. Efek antidiabetik yang paling tinggi ditunjukkan oleh pemberian ekstrak etanol R.mucronata dosis 625 mg/kgBB.Kata kunci: Rhizopora mucronata, Fitokimia, Staphyllococcus aureus, Eischerichia coli, Antidiabetik, dan Antimikrob

Antioxidant, Antibacterial, and Antidiabetic Activities of Roselle (Hibiscus sabdariffa) Extracts

Hibiscus sabdarif a L., also referred to as roselle, is commonly utilized in the pharmaceutical and food industries. Roselle contains bioactive compounds such as phenolics, alkaloids, tannins, flavonoids, saponins, and organic acids, which have pharmacological properties, such as antioxidant, antibacterial, immune booster, antidiabetic, anti-inflammatory, and anti-hypertensive properties. There are many studies regarding the pharmacological activities of roselle extract and its applications. However, there has been no research to study the effectiveness of the solvent in testing roselle petal extracts against antibacterial, antioxidant, and antidiabetic activities, simultaneously. This research used two kinds of polar solvents, dH2O and ethanol, with various concentrations for antibacterial activity test by five pathogenic bacteria, for antioxidant test by the DPPH method, and for antidiabetic test by the alpha-glucosidase inhibition method. The result showed that the ethanol extract of roselle had higher antibacterial activity compare to the roselle water extract. Antioxidant activity of roselle ethanol extract at 20% concentration had the highest activity 69.75 ± 0.002%; while, the 100% concentration of roselle water extract had the highest antioxidant activity 138.73 ± 0.013%. antidiabetic activity of roselle ethanol and water extract at 100% concentration had the highest activity 1,195.44 ± 0.007% and 1,552.49 ± 0.069%, respectively

OPTIMALISASI PENCAHAYAAN ALAMI TERKAIT KESEHATAN LANSIA PADA PANTI JOMPO DI JAKARTA BARAT

OPTIMALISASI PENCAHAYAAN ALAMI TERKAIT KESEHATAN LANSIA PADA PANTI JOMPO DI JAKARTA BARAT

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