In vitro studies of antistress and antiallergic effects of semecarpus anacardium fruit in asthma

Semicarpus anacardium Linn. (Anacardiaceae) is a deciduous moderate sized tree. The plant is commonly known as Ballataka (Sanskrit), Bhela (Hindi) and marking nut in English. Fruits are acrid and sweet and used traditionally in the treatment of asthma. Allergy and stress are important contributing factors in asthma; hence, our objective was to study the effect of plant extracts on milk-induced leucocytosis (antistress) and milk-induced eosinophilia (antiallergic) as no work is done in this direction and to check a possible antiasthmatic role of the plant. Extracts were given at the dose of 50 and 100 mg/kg, p.o., to mice. Ethyl acetate and ethanol extracts showed significant decrease in leukocytes and eosinophils count. These results confirm the use of S. anacardium fruits as antistress and antiallergic agents in the treatment asthma.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Synthesis and evaluation of some substituted mercaptothiazoles and their derivatives of biological interest

439-441The title compounds have been synthesized from 4-(4'chlorophenyl)-Δ4 - thiazoline-2-thione l , which in turn is synthesized by the react ion of p-chlorophenacyl bromide with ammonium dithiocarbamate. Compound 1 on treatment with N-chloroacetylated anilines furnishes the title compounds. The compounds have been tested for their antimicrobial activity

Synthesis and evaluation of some new substituted phenylthiazole derivatives and their antitubercular activity

1033-1037A new series of substituted phenylthiazole derivatives have been synthesized and the structures of these compounds have been established on the basis of spectral and elemental analysis. All compounds have been screened for antitubercular activity by Middle brook 7H9 agar medium against H37Rv. strain. Most of these compounds have shown promising antitubercular activity

Synthesis and evaluation of some novel substituted 1,3,4-oxadiazole and pyrazole derivatives for antitubercular activity

1453-1456A series of 1,3,4-oxadiazole and pyrazole derivatives have been synthesized and evaluated for antitubercular activity. All the structures of the newly synthesized compounds have been supported by IR, 1H NMR, MS and CHN analysis. All the compounds have shown promising antitubercular activity when compared with the standard drug Streptomycin

Studies on the Synthesis of Novel 2,4-ThiazolidinedioneDerivatives with Antidiabetic Activity: Synthesis of 2,4-thiazolidinedione derivatives

A new series of thiazolidinedione derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and elemental analysis. All of the compounds were screened for antidiabetic activity on albino rats.Most of the compounds showed significant antidiabetic activity when compared with the standard drug glibenclamide

Synthesis of <i>N</i>-3(4-(4-chlorophenyl thiazole-2-yl)-(2-(amino)methyl)-quinazoline-4(3<i style="">H</i>)-one and their derivatives for antitubercular activity

1778-1781A new series of N-3[4-(4-chlorophenyl thiazole-2-yl)-2-amino methyl] quinazoline-4(3H)-one and their derivatives are synthesized. The structures of the title compounds are confirmed on the basis of IR and 1H NMR. The compounds are screened for their antitubercular activity, using H37Rv strain on L J medium. All the compounds have showed moderate to promising antitubercular activity

Current biological and synthetic profile of Triazoles: A review

International audienc

Synthesis and evaluation of some novel 1,2,4-triazole derivatives for antmicrobial, antitubercular and anti-inflammatory activities

297-301A series of 1,2,4-triazole derivatives have been synthesized and evaluated for antimicrobial, antitubercular and anti-inflammatory activities. The newly synthesized compounds have been characterized by IR, 1H NMR and CHN analysis. All the compounds have shown promising antimicrobial, antitubercular and anti-inflammatory activities when compared with standard drug Norfloxacin, <span style="mso-bidi-font-weight: bold">Griseofulvin, Streptomycin and Diclofenac sodium respectively. </span

Synthesis and Evaluation of Some 1,4-Dihydropyridine and Their Derivatives as Antihypertensive Agents.

698-701A series of 1, 4-dihydro-2, 6-dimethyl-4-{4-[3-(2-aminopyrazine/1-amino-4-methyl piperazine)-2-hydroxy propoxy]-phenyl}-pyridine-3, 5-carbamoyl have been synthesized and the structure of the compounds have been confirmed by IR, ¹H NMR , MS & elemental analysis. The title compounds have been evaluated for antihypertensive activity by tail-cuff method. Some of these compounds have been found to exhibit excellent antihypertensive activity