SUN PROTECTIVE POTENTIAL OF POLYHERBAL SKIN CARE CREAM

Objective: Evaluation of sun protective potential of polyherbal skin care cream Methods: In vitro sun protection factor of polyherbal cream of Centella asiatica, Azadirachta indica, Ocimum sanctum and Hibiscus rosa sinensis was determined by spectrophotometric method using UV visible spectrophotometer. Results: The formulation F4 was found most satisfactory in all parameter evaluated with good sun protection potential, so it could be used as effective sun protective agent. Conclusion: Herbal cosmetics were recognised as a safe, better and effective alternative of synthetic cosmetics that could help to protect and promote skin health naturally without any side effects. The herbal cream F4 was found good sun protection potential against the damaging effects of UV radiations

Effect of Turning Lane at Busy Signalized At-Grade Intersection under Mixed Traffic in India

Traffic congestion on urban roads has become a serious concern, particularly, at intersections. The performance of an intersection controls the performance of urban roads meeting at that intersection. The paper presents the effect of addition of turning lane in the middle of approach road at busy signalized at-grade intersection, narrowing the width of all lanes to keep total road width the same, in heterogeneous traffic. The traffic at intersection comprises both of vehicles and pedestrians. Their interactions along with signal cycle decide the efficiency of an intersection. A microscopic simulation tool VISSIM, has been used to model the heterogeneous (mixed) traffic under constraints of roadway geometry, vehicle characteristics, driving behaviour and traffic controls. The effect is investigated with different random seeds to obtain reasonable results for analysis. The performance evaluation is done in terms of vehicle throughput, average queue length, maximum queue length, average delay time per vehicle, average speed and emission of Carbon monoxide CO, mono-nitrogen oxides NOx, Volatile organic compounds (VOC) etc. It has been observed that on adding turning lane in the middle, of approach road the average queue length, maximum queue length, average delay time per vehicle and emission per vehicle get considerably reduced, while there is an increase in vehicle throughput and average speed of all the vehicles. The results reported in this paper clearly shows that addition of turning lane in existing intersection can reduce congestion considerably, enhancing performance of intersections and network

Secrecy of WSN Data Over Nakagami m Fading Channels with Selection Combining Diversity

We consider the security of wireless sensor network (WSN) data over Nakagami – m fading channels at the physical layer. A WSN in which the fusion center performs selection diversity has been considered for better quality reception. The links between the WSN node and fusion center are assumed to follow Nakagami-m fading distribution. Closed-form expressions for secrecy outage probability (SOP) are derived, and it is established that SOP analysis also leads to the analysis of the existence of secrecy as a special case of SOP. The analytical expressions have been validated through results from simulations. The analysis is valid for all positive real values of the fading parameter, m. The limits on the signal-to-noise ratio can be obtained to secure the transmitted data against eavesdropping with the required SOP and secrecy rate using the analysis presented in this paper

Optimizing Performance of at-grade Intersection with Bus Rapid Transit Corridor and Heterogeneous Traffic

ABSTRACTBus Rapid Transit (BRT) has emerged as a preferred mode of public transport in various countries all over the world for its cost effectiveness in construction as well as in operation and maintenance. The rapid transit feature of BRT is seen as a solution to many traffic problems in these countries. However, in developing countries like India, the right -of-way for most of the roads is restricted and traffic is heterogeneous in nature. Provision of BRT in existing right -of-way reduces the capacity available for other motorized traffic. As the buses travel with a certain frequency on dedicated bus- ways, the dedicated corridor remains unused for most of the period when other traffic on motorized vehicle (MV) lanes suffers from congestion. The problem gets severe at intersections. However, if buses are operated in mixed traffic it is no more rapid transit. Hence, a solution is required to address this problem and optimize the performance of traffic as a whole. This paper presents the effect if dedicated bus-ways end at a reasonable distance before the stop line at a busy signalized at-grade intersection, and bus lanes (beyond that) are made available to all the motorized vehicular traffic (heterogeneous traffic) at intersection. The performance evaluation is done in terms of average queue length, maximum queue length, average delay time per vehicle, vehicle throughput, average speed in network and emission of Carbon monoxide CO, mono-nitrogen oxides NOx and Volatile organic compounds (VOC). It is observed that availability of bus lanes to other motorized traffic for a reasonable distance before intersection considerably reduces the average queue length, maximum queue length, average delay time per vehicle and emission per vehicle, while there is an increase in vehicle throughput and average speed of all the vehicles in the network. Thus it results in reduction of congestion and performance enhancement of at-grade intersections and network. Results of investigation are relevant in international context. VISSIM, a microscopic simulation tool, is used to model the heterogeneous traffic and public transit lines under constraints of roadway geometry, vehicle characteristics, driving behaviour and traffic controls. The effect is investigated with different random seeds to obtain reasonable results for analysis

Effect of Loading Rate on Creep Properties of HgCdTe Epitaxial Films

Nanoindentation creep studies were performed on Hg1-xCdxTe (x~0.29) epitaxial films using different loading rates of 0.5 mN.s-1, 1 mN.s-1, 2 mN.s-1 and 4 mN.s-1, keeping a constant peak load of 10 mN. A constant hold time of 20 sec at peak load was maintained for all experiments. The effect of loading rate on creep behaviour of material has been investigated. Creep displacement had shown increasing trend with increase of loading rates. Stress exponents were extracted using creep curve fitting with an empirical equation. A strong dependence of loading rate on stress exponent was observed. The value of stress exponent was found varying in the range 0.60-1.76, 0.96-2.23, 0.98-2,87 and 0.90-2.81 for loading rates 0.5 mN.s-1, 1 mN.s-1, 2 mN.s-1 and 4 mN.s-1, respectively. The change of stress exponent was attributed to change of creep mechanism. Hardness and elastic modulus were extracted from load-displacement curves and it was found that with the increase of the loading rate hardness increases, while elastic modulus remains constant. A correlation between variation of hardness and creep displacement has also been presented

IN-VITRO AND IN VIVO STUDIES OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES

Nanoparticles speak to one of the appealing choices in the compelling treatment of tumor chemo-treatment. In the present work, definition and improvement of a novel Cetuximab (MTX)- stacked biodegradable nanoparticles utilizing poly(D,L-lactide-co-glycolide) (PLGA) was done. The arranged nanoparticles were assessed for physicochemical properties, for example, molecule measure, zeta potential, discharge thinks about, and so forth. Molecule size of upgraded definition was < 200 nm. Our essential outcomes exhibit that the created Cetuximab-stacked PLGA nanoparticles discharging the medication for delayed timeframe. Keywords: Cetuximab; PLGA 50:50; nanoparticle

A Comprehensive Survey of Data Mining Techniques on Time Series Data for Rainfall Prediction

Time series data available in huge amounts can be used in decision-making. Such time series data can be converted into information to be used for forecasting. Various techniques are available for prediction and forecasting on the basis of time series data. Presently, the use of data mining techniques for this purpose is increasing day by day. In the present study, a comprehensive survey of data mining approaches and statistical techniques for rainfall prediction on time series data was conducted. A detailed comparison of different relevant techniques was also conducted and some plausible solutions are suggested for efficient time series data mining techniques for future algorithms.

FORMULATION AND EVALUATION OF DOXORUBICIN CONTAINING NANOGELS FOR DELIVERY TO CANCER CELLS

The objective of this study is to prepare nanogels were prepared via charged gellan gum. It was prepared by in situ cross linking reaction between two oppositely charged materials by green method without use of chemical cross linking agents. The prepared nanogels were characterized by Dynamic light scattering, scanning electron microscopy, differential scanning calorimetry and X- Ray diffractometry. The prepared formulation had average particle size of 226 nm with polydispersity index of 0.3. The doxorubicin loaded nanogel demonstrated sustained release for 20 h. The prepared nanogels were hemocompatible and cyctocompatible as revealed by hemocompatibility and MTT assay respectively. All results confirmed that these nanogels can be used for cancer treatment. Keywords: Nanogel, Chitosan, Gellan gum, Doxorubicin, Cancer

Cathodoluminescence Studies of Nanoindented CdZnTe Single Crystal Substrates for Analysis of Residual Stresses and Deformation Behaviour

Nanoindentation-induced residual stresses were analysed on (111) Te face CdZnTe single-crystal substrates in this study. CdZnTe substrates were subjected to nanoindentation using cube corner indenter geometry with a peak load of 10 mN. Loading rates of 1 mN/s and 5 mN/s were used in the experiments, with a holding time of 10 s at peak load. Residual stresses on the indented region were analysed from load-displacement curves and explained using dislocation generation and elastic recovery mechanisms. Residual stresses were found to be of compressive type, just on the indented surface. The slip lines along the slip directions of this material were clearly visible in the FE-SEM images of the indents. Indents and surrounding surfaces were characterized using the Cathodoluminescence (CL) technique. CL mapping of the indented surface revealed the dislocation generation and their propagation behaviour just beneath the indenter as well as in the surrounding surfaces. The dislocations act as non-radiative recombination centres and quench the CL intensity locally. Dark lines were explained as the presence of dislocations in the material. CL mapping analysis shows that both the rosette glide and tetrahedral glide of dislocations are the primary deformation mechanisms present in CdZnTe. A rosette structure was observed in the CL mapping. CL spectra at 300 K of un-deformed CdZnTe show a peak at 810 nm wavelength, which corresponds to near-band-edge emission. After indentation, the CL spectra show the peak intensity at 814 nm and 823 nm wavelengths at the edge of the indents created with a loading rate of 1 mN/s and 5 mN/s, respectively. These peak shifts from 810 nm were attributed to the tensile residual stresses present in the indented material