PHARMACEUTICAL STUDY OF HEMGARBHA POTTALI RASA

The Pottali rasayana is a unique preparation in Ayurveda as it is very compact in structure and quick acting due to its high potency. Hemgarbha pottali rasa is a medicine which is known as emergency medicine of Ras shastra because of its efficacy and its quick effect in condition like Sannipataj awastha. It is prepared with the combination of Shudha parada, Shudha gandhaka, Shudha tamra bhasma and Shudha swarna. Preparation method of this Hemgarbh pottali ras is unique in the way that it is prepared in molten sulphur which increases its efficacy many folds. Inspite of availability of vast theoretical description in Ayurvedic texts regarding Pottali rasayana, very less research work is carried out on Hemgarbh pottali rasa, so it is mostly out of practice in Ayurvedic community. Hemgarbh pottali rasa is a very potent medicine which should be made popular by Ayurvedic practitioners. In the present article various methods of preparation of Hemgarbh pottali rasa has been described and most common method of preparation which is molten sulphur method is discussed in detail

Machine learning Based Bearing Fault Classification Using Higher Order Spectral Analysis

In the defense sector, where mission success often hinges on the reliability of complex mechanical systems, the health of bearings within aircraft, naval vessels, ground vehicles, missile systems, drones, and robotic platforms is paramount. Different signal processing techniques along with Higher Order Spectral Analysis (HOSA) have been used in literature for the fault diagnosis of bearings. Bispectral analysis offers a valuable means of finding higher-order statistical associations within signals, thus proving to detect the nonlinearities among Gaussian and non-Gaussian data. Their resilience to noise and capacity to unveil concealed information render them advantageous across a range of applications. Therefore, this research proposesa novel approach of utilizing the features extracted directly from the Bispectrum for classifying the bearing faults, departing from the common practice in other literature where the Bispectrum is treated as an image for fault classification. In this work vibration signalsare used to detect the bearing faults. The features from the non-redundant region and diagonal slice of the Bispectrum are used to capture the statistical and higher-order spectral characteristics of the vibration signal. A set of sixteen machine learning models, viz., Decision Trees, K-Nearest Neighbors, Naive Bayes, and Support Vector Machine, is employed to classify the bearing faults. The evaluation process involves a robust 10-fold cross-validation technique. The results reveal that the Decision Tree algorithm outperformed all others, achieving a remarkable accuracy rate of 100 %. The naive Bayes algorithm also demonstrated the least performance, with an accuracy score of 99.68 %. The results obtained from these algorithms have been compared with those achieved using Convolutional Neural Network (CNN), revealing that the training time of these algorithms is significantly shorter in comparison to CNN

Tackling water and food crisis in South Asia: Insights from the Indo-Gangetic Basin

CPWF-IWMI “Basin Focal Project for the Indus-Gangetic Basin” is an initiative by the CPWF, to identify steps to be taken towards integrated management of the IGB’s water and land resources to improve productivity and ensure future sustainability of all production and ecosystems in the basin. The project was developed with the objective of conducting basin-wide analysis of the conditions, constraints and opportunities for improving agricultural water productivity and alleviating poverty through high potential interventions. This objective was accomplished through rigorous analysis and mapping of water availability and access, poverty, and productivity of water and identifying potential interventions that contribute to improved water productivity and poverty alleviation in the Indo-Gangetic basin

COMPARATIVE STUDY OF THE RELATIVE EFFICACY OF KUMKUMADI CREAMS (WITH VARIOUS WATER AND OIL PHASE) FOR THEIR VYANGAHAR EFFECT

The importance of beauty and personality is increasing now a day as it is a competitive era. Along with increased demand of beautification, the problems are also increasing which cause damage to beauty or personality due to changed life style and polluted atmosphere. Among the personality damaging disorder or dis-beautifying conditions, Vyanga is such a condition which affects the beauty as well as personality. Many people are suffering from Vyanga today, among them women are commonly found due to changes occurring during pregnancy and use of cosmetics supplements. Vyanga is a KshudraRoga (skin disorder) affecting the skin for which many internal medicine and external applications are suggested in texts. Local application is more useful in skin disorders as it directly act on lesion. In the context of Vyanga, Kumkumadi Taila has been strongly suggested as it directly acts on the site of lesion and all its contents possess coloring and depigmentation properties.Kumkumadi cream with different bases was given to total 38 patients registered divided in three groups for duration of one month. All the three creams were found significantly effective (p<0.01) on moisture content of skin, size of lesion, color of lesion, itching and burning sensation of lesion. Among three, Kumkumadi cream no.2 was found most effective with relief of 67.94% in treating disease Vyanga

Plasmacytoma of Bronchus Treated by Radical Radiotherapy-A Rare Case with Four and a Half Years Follow up

AbstractPlasmacytoma of the bronchus is a very rare plasma cell neoplasm affecting the bronchus. Here we report a case of plasmacytoma of the bronchus treated by radical radiotherapy in July 2002. The tumor responded very well to treatment and showed a slow but sustained regression in the size over two years. Presently, he has completed four and a half years of follow-up and is free of disease

Rabies Virus Infection in Domestic Buffaloes and Wild Animals in India

Rabies is one of the most significant diseases in India with severe health implication to humans, domestic and wild animals. In the present study, four concomitant incidents of rabies related deaths were recorded in the western province of India, Gujarat during 2012 - 2014. Brain samples were collected from two buffaloes, nilgai, and mongoose during these incidents and rabies virus was identified from these samples. Further genetic relationship of these isolates was determined and the rabies virus transmission among the wild and domestic mammals was established. Molecular epidemiology based on the glycoprotein ecto-domain and complete nucleoprotein gene showed that all the four isolates belonged to Arctic-like 1 lineage which is predominant in India. Phylogenetic analysis and time scaled evolutionary tree analysis indicated that the wild animals are playing an important role in the maintenance and also transmission of the rabies virus in India

Nonlinear Stability in the Generalised Photogravitational Restricted Three Body Problem with Poynting-Robertson Drag

The Nonlinear stability of triangular equilibrium points has been discussed in the generalised photogravitational restricted three body problem with Poynting-Robertson drag. The problem is generalised in the sense that smaller primary is supposed to be an oblate spheroid. The bigger primary is considered as radiating. We have performed first and second order normalization of the Hamiltonian of the problem. We have applied KAM theorem to examine the condition of non-linear stability. We have found three critical mass ratios. Finally we conclude that triangular points are stable in the nonlinear sense except three critical mass ratios at which KAM theorem fails.Comment: Including Poynting-Robertson Drag the triangular equilibrium points are stable in the nonlinear sense except three critical mass ratios at which KAM theorem fail

Vibrio parahaemolyticus, enterotoxigenic Escherichia coli, enterohemorrhagic Escherichia coli and Vibrio cholerae

This review highlighted the following: (i) pathogenic mechanism of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, especially on its cardiotoxicity, (ii) heat-labile and heat-stable enterotoxins produced by enterotoxigenic Escherichia coli, especially structure–activity relationship of heat-stable enterotoxin, (iii) RNA N-glycosidase activity of Vero toxins (VT1 and VT2) produced by enterohemorrhagic Escherichia coli O157:H7, (iv) discovery of Vibrio cholerae O139, (v) isolation of new variant of Vibrio cholerae O1 El Tor that carries classical ctxB, and production of high concentration of cholera toxin by these strains, and (vi) conversion of viable but nonculturable (VBNC) Vibrio cholerae to culturable state by co-culture with eukaryotic cells