Common Fixed Points of Compatible Maps in Fuzzy Metric Spaces

In this Paper a transposition of these notions is being made for 4-tuples A, B, C and D of self maps of fuzzy metric space (X, d). Then under suitable contractive conditions some common fixed point theorems involving such maps are stated and proved. These results open, in our opinion, a wider scope for the study of this topic in the framework of this new fuzzy metric space

A Design Based New Reusable Software Process Model for Component Based Development Environment

AbstractSoftware development considered to be an important part of software industry. Various metrics, algorithms and reusable process models has been designed but ultimately our main goal is only to find that part which will help us to select the optimal one which may be a metric, algorithm or a reusable software process model. For the various large applications some components need to be built separately and some of the components need to be modified according to the requirement for searching the optimal components. Now a day's component based software engineering considered to be the best approach for the software development at low cost and this software development best approach will totally dependent on the optimal selection of components. The aim of this paper is to describe the characteristics of some selected state of art CBSD models and a new reusable software process model has been designed for the optimal selection of components based on the new optimal algorithm

Analyzing the Performance of Different Classifier for Detecting Polarity of Customer Reviews

To determine an author's emotional state from their written words is the focus of sentiment analysis, a subfield of NLP. This study focuses on the many techniques used to categorize the text reviews written in natural language according to the viewpoints expressed therein, in order to determine if the widespread behavior is positive, negative, or neutral. Streaming of thoughts and expression of opinion have been facilitated by the proliferation of debate forums, Weblogs, product review sites, e-commerce, and social networking sites. A lot of people's feelings, reviews, and assessments of others' opinions can be found on social media. This research ranks the top classifier for feelings using data derived from online product reviews posted to Twitter. Experimental work on polarity classification with well-known classifiers such as Naive byes, Support vector machine, and Logistic regression for anticipating testimonials was addressed

Effect of Hagedorn States on Isothermal Compressibility of Hadronic Matter formed in Heavy-Ion Collisions: From NICA to LHC Energies

In this work, we have studied the isothermal compressibility ($\kappa_T$) as a function of temperature, baryon chemical potential and centre-of-mass energy ($\sqrt{s_{NN}}$) using hadron resonance gas (HRG) and excluded-volume hadron resonance gas (EV-HRG) models. A mass cut-off dependence of isothermal compressibility has been studied for a physical resonance gas. Further, we study the effect of heavier resonances ($>$ 2 GeV) on the isothermal compressibility by considering the Hagedorn mass spectrum, ${\rho}(m)\sim{\exp(bm)}/{(m^2+m_0^2)^{5/4}}$. Here, the parameters, $b$ and $m_0$ are extracted after comparing the results of recent lattice QCD simulations at finite baryonic chemical potential. We find a significant difference between the results obtained in EV-HRG and HRG models at a higher temperatures and higher baryochemical potentials. The inclusion of the Hagedorn mass spectrum in the partition function for hadron gas has a large effect at a higher temperature. A higher mass cut-off in the Hagedorn mass spectrum takes the isothermal compressibility to a minimum value, which occurs near the Hagedorn temperature ($T_H$). We show explicitly that at the future low energy accelerator facilities like FAIR (CBM), Darmstadt and NICA, Dubna the created matter would be incompressible compared to the high energy facilities like RHIC and LHC.Comment: Same as published pape

Chrono-Geographical Analysis Of Sars-Cov2 Genome Wide Mutations

Since the reporting of the first cases of coronavirus in China and the publication of the first sequence of SARS-CoV-2 in December 2019, the virus has undergone numerous mutations. In the present study, we gathered 1,404 SARS-CoV-2 complete genomes from the NCBI and detected the mutations via GISAID. We analysed and annotated all SARS-CoV-2 mutations compared with the reference Wuhan genome NC_045512.2. The S1B domain (333-527) of the spike protein was found the highest mutating region in the entire genome whereas NS6 protein was found the lowest mutating region. Interestingly, no any mutation was detected from NSP11 protein. The D614G from spike protein, T81I from NSP2, A890D from NSP3, L37F from NSP6, P323L from NSP12, Q57H from NS3 and Y73C from NS8 were identified in maximum numbers of SARS-CoV-2 populations from all six continents. Many co-occurring mutations were detected in spike proteins, N proteins and NSP12 proteins. The deletions were only found in S, N, NSP1, NSP2, NSP3, NSP4, NSP6, NS7a and NS7b proteins. The co-occurring deletions were identified only in N, NSP1 and NSP6 proteins. A few insertion mutations were identified in spike proteins and NSP6 proteins. But the high prevalence of stop-codon mutations was detected in spike, NSP6, NS7b and NS8 proteins. Our results provide an in-depth analysis of SARS-COV-2 whole genome which we believe, can shed light in the understanding of SARS-COV-2 pathogenesis and mutation pattern which can aid in the development of prevention methods as well as future research into the pathogenesis of SARS-CoV-2 and therapeutic development

INSECTICIDAL AND GENOTOXIC POTENTIAL OF ACORUS CALAMUS RHIZOME EXTRACT AGAINST DROSOPHILA MELANOGASTER

ABSTRACTObjectives: Insect pest problems in agriculture have a considerable shift during first decade of 21st century due to global climate changes. Varioussynthetic insecticides were used from last 50 years to overcome the pest problem, but major concerns in using these pesticides were: Public healthand pesticide resistance in pests. To abolish the catastrophic effect of synthetic insecticides, urgent need to develop new drugs for pest control. In thisstudy we evaluate the insecticidal and genotoxic activity of ethanolic extract of Acorus calamus rhizome against Drosophila melanogaster.Methods: Different concentration of ethanolic extracts of A. calamus, fed to different developmental stages of D. melanogaster to determine insecticidalactivity and genotoxicity; genotoxicity was determined by the comet assay in male flies.Results: Lethal concentration 50 (LC50) values of ethanolic extract against larvae, adult males and females of D. melanogaster were 109.54, 52.51 and41.11 mg/L respectively. Genotoxicity of adult's flies were determined at 30 and 55 mg/L ethanolic extract of A. calamus, The mean comet tail lengthwas 4.24±0.653 μm and 6.13±0.721 μm and the respective DNA damage was 5.1% and 7.3% with reference to controls.Conclusion: The present finding suggests that ethanolic extract of A. calamus rhizome showed higher insecticidal potential in adults than larvaeof D. melanogaster. Results from genotoxicity studies further support the insecticidal activity against adult stages of D. melanogaster. The studyreflects ethanolic extract of A. calamus could be used as an alternative pest control negotiator for minimizing the noxious effects of pesticides in theenvironment.Keywords: Insecticidal activity, Genotoxicity, Ethanolic extract, Botanical pesticides, Acorus calamus, Drosophila melanogaster

The role of Swarna Bhasma in the treatment of Autoimmune disease

According to Ayurveda point of view Swarna Bhasma is considered as the best medicine for various disease. Swarna Bhasma is frequently used in the treatment of autoimmune disorder. It is considered as best remedy in the treatment of rheumatoid arthritis, Ankylosing Spondolosis, SLE (Systemic lupus erythematosus), Multiple sclerosis, GBS (Guillen Barry Syndrome), Myasthenia gravis etc. The Karma of Swarna Bhasma is Vrishya, Brimhana, Medhya, Hridya, Balya, Rasayan, Vajikarana, Smritiprada, Tridoshaghana, Yogwahi, Chkshusya, Ojovridhhikara etc. The indication of Swarna Bhasma is in Prameha, Rajayakshama, Unmada, Jwara, Pandu, Swasa, Kasa, Aruchi, Agnimandya, phthisis, loss of vitality, burning sensation, acidity, microbial infection, toxicity, infertility etc. It can be used in all diseases along with different adjuvants or other medium or herb to speed up the recovery process and to increase the body resistance diseases. Swarna Bhasma is potent antitoxin, immunomodulatory, nootropic, antirheumatic, antimicrobial and antiviral in addition. It is also a nervine tonic. Swarna Bhasma overall acts on all organs in the body, especially it acts on nerves, brain, lungs

Radial Flow and Differential Freeze-out in Proton-Proton Collisions at s=7\sqrt{s}= 7 TeV at the LHC

We analyse the transverse momentum ($p_{\rm T}$)-spectra as a function of charged-particle multiplicity at midrapidity ($|y| < 0.5$) for various identified particles such as $\pi^{\pm}$, $K^{\pm}$, $K_S^0$, $p+\overline{p}$, $\phi$, $K^{*0} + \overline {K^{*0}}$, and $\Lambda$ + $\bar{\Lambda}$ in proton-proton collisions at $\sqrt{s}$ = 7 TeV using Boltzmann-Gibbs Blast Wave (BGBW) model and thermodynamically consistent Tsallis distribution function. We obtain the multiplicity dependent kinetic freeze-out temperature ($T_{\rm kin}$) and radial flow ($\beta$) of various particles after fitting the $p_{\rm T}$-distribution with BGBW model. Here, $T_{\rm kin}$ exhibits mild dependence on multiplicity class while $\beta$ shows almost independent behaviour. The information regarding Tsallis temperature and the non-extensivity parameter ($q$) are drawn by fitting the $p_{\rm T}$-spectra with Tsallis distribution function. The extracted parameters of these particles are studied as a function of charged particle multiplicity density ($dN_{ch}/d\eta$). In addition to this, we also study these parameters as a function of particle mass to observe any possible mass ordering. All the identified hadrons show a mass ordering in temperature, non-extensive parameter and also a strong dependence on multiplicity classes, except the lighter particles. It is observed that as the particle multiplicity increases, the $q$-parameter approaches to Boltzmann-Gibbs value, hence a conclusion can be drawn that system tends to thermal equilibrium. The observations are consistent with a differential freeze-out scenario of the produced particles.Comment: Published versio

Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines

Xylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feature during recovery period. Biphasic P wave, biphasic T wave, and depressed PR segment were common electrocardiographic findings. Biochemical attributes were within physiological limits except a significant increase in ALT values during anaesthesia. The values returned to normal during recovery ruling out any renal or hepatic toxicity. Occasionally, negative T wave, notched P wave, and sinus block were noticed. It is recommended that the anaesthetic combinations xylazine-butorphanol-guaifenesin-ketamine can be safely used for short-term total intravenous anaesthesia (TIVA) in equines under field conditions

Repellant effect of neem formulation and aqeuous extract of Melia azedarach on greenhouse whitefly (Trialeurodes vaporariorum Westwood, Hemiptera: Aleyrodidae)

The present study assessed the repellence activities of two biopesticides viz. a formulation of neem, neem baan and aqueous extract of Melia azedarach (Dharek) kernels against crawlers of greenhouse whitefly Trialeurodes vaporariorum (Westwood) (Hemiptera: Aleyrodidae). The maximum repellency (22.07%) was recorded at 10 % concentration of dharek extract followed by Neem Baan at 0.0025 % concentration (18.33%). The minimum repellency (4.71%) was observed at 0.0005 % concentration of Neem baan. These results indicate a potential use of neem baan and aqueous dharek kernel extracts in management of greenhouse whitefly