In situ chemichromic studies of interactions between a lutetium bis-octaalkyl-substituted phthalocyanine and selected biological cofactors

This article is available open access through the publisher’s website at the link below. Copyright @ 2011 The Royal Society.Spin-coated films, approximately 100 nm thick, of a newly synthesized bis[octakis(octyl)phthalocyaninato] lutetium(III) complex on ultrasonically cleaned glass substrates exhibit pronounced chemichromic behaviour with potential application in healthcare. In situ kinetic optical absorption spectroscopic measurements show that the phthalocyanine Q-band is red shifted by 60 nm upon oxidation arising from exposure to bromine vapour. Recovery to the original state is achieved by the treatment of the oxidized films with nicotinamide adenine dinucleotide and l-ascorbic acid (vitamin C) in an aqueous solution containing 1.5 M lithium perchlorate. The neutralization process is found to be governed by first-order kinetics. The linear increase of the reduction rate with increasing concentration of cofactors provides a basis for calibration of analyte concentrations ranging from 3.5 mM down to 0.03 mM.Air Force Office of Scientific Research, Air Force Material Command, USAF and the Leverhulme Trust

Migration, Language Policies and Language Rights in Luxembourg

This paper deals with the state of language rights in Luxembourg in the light of immigration and the multilingualism associated with it. Although Luxembourg might appear to be an ideal case of multilingualism with three official languages (Luxembourgish, French, and German), the reality is very different because its language policies are marked by a hierarchy: while Luxembourgish has the symbolic dominance as the ‘national language’, French is the preferred language in the workplace and administration. The situation has become complex due to the steady influx of immigrants since the 1970s. Currently, more than 40 per cent of Luxembourg’s population consists of foreigners, and this has changed the linguistic situation in the sense that Portuguese has become one of the most widely spoken languages in Luxembourg, although it does not enjoy any legal safeguards. Taking account of this multilingual scenario, this paper examines the rights of different linguistic communities in Luxembourg. On the one hand, there is the need to protect Luxembourgish, which is the majority language in Luxembourg but a minority language when compared to other national languages of Europe, while, on the other hand, the needs of its Portuguese-speaking community also have to be taken into account since the use of German as the medium of instruction at primary level disadvantages them. Finally, the paper will also consider the role and the future of the other two main languages (French and German)

Performance analysis of non-circular microchannels flooded with CuO-water nanofluid

This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute.In this study the performances of various non-circular microchannel heat sinks (normalized with circular shape) have been comparatively analyzed for CuO-water nanofluid and baseline pure water flow. Nusselt number and Poiseuille number for each microchannel and thermo-physical properties of CuO-water nanofluid (viz., thermal conductivity, viscosity, specific heat and density) have been designed either empirically or from literature. Results for trapezoidal shape gives highest normalized pressure drops among all cases. Thermal performances for constant heat flux and constant wall temperature boundary conditions have been assessed in terms of normalized outlet wall temperature and normalized heat exchange rate. Results show that when thermal performance of any microchannel heat sink (MHS) improves, the hydraulic performance deteriorates. Trapezoidal microchannel gives best thermal performance in terms of normalized heat exchange rate specially with CuO-water nanofluids flow

Printed graphene films with positive temperature coefficient of resistivity

0.5μm thick graphene films printed on plastic substrates exhibit metallic type conduction with a positive value of 1.5×〖10〗^(-3) K^(-1) for the temperature coefficient of resistance over the temperature range from 260K to 330K . The crystallites of approximately 6.5 nm in their average size in the film are found from the X-Ray diffraction pattern to be oriented preferentially along [002] plane.Dr. Indrani Banerjee is grateful to Commonwealth Association, UK for funding the present research work under the fellowship placement scheme (grant reference INCF-2014-66). The studentship of Ms Faris is partially sponsored by the Air Force Office of Scientific Research, Air Force Material Command, USAF, under Grant No. FA8655-08-1-3056

Management of pelvic fractures in dog

Pelvic fractures are common sequelae of major traumatic injury of dogs and cat which, comprise of at least 25% of all fractures in veterinary practice (Piermattei et al., 2006). Fracture of ilium, the most common fracture seen in the pelvis account for 46% of all pelvic fracture (Henry, 1985; De Camp, 2005). Whereas, acetabular fracture comprises 12 % of pelvic fractures in dogs (De Camp, 2005). In smaller dogs, most of the pelvic fractures recover without surgery. But immediate surgery is required within 72 hours if the fracture is unstable (Harasen, 2007). We hereby report the successful surgical management of unstable fracture of ilium and ischium of pelvis in a Spitz dog

A simple and efficient method for extraction of genomic DNA from tropical tuber crops

DNA extraction in many plants is difficult because of metabolites that interfere with DNA isolation procedures and subsequent applications, such as DNA restriction, amplification and cloning. We havedeveloped a reliable and efficient method for isolating genomic DNA free from polysaccharide, polyphenols and protein contaminants from tropical tuber crops (Elephant foot yam, Cassava, Sweetpotato Taro and Tannia). The method involves inactivation of contaminant proteins by using CTAB/Proteinase K and precipitation of polysaccharides in the presence of high concentration of salt.The purity of genomic DNA was confirmed by A260/280 and A260/230 ratios calculated from the spectrophotometric readings and further by restriction analysis of the isolated DNA using restriction enzymes EcoRI and Hind III. The described protocol also resulted in the isolation of sufficiently higher yield of DNA from leaf sample of tropical tuber crops. The new protocol can be successfully used forboth small and large scale preparation of genomic DNA from leaf tissues of tuber crops which is highly suitable for further down stream processes like PCR amplification and restriction digestion analysis

Fast Dissolving Tablets of Aloe Vera Gel

Purpose: The objective of this work was to prepare and evaluate fast dissolving tablets of the nutraceutical, freeze dried Aloe vera gel. Methods: Fast dissolving tablets of the nutraceutical, freeze-dried Aloe vera gel, were prepared by dry granulation method. The tablets were evaluated for crushing strength, disintegration time, wetting time, friability, drug content and drug release. A 32 full factorial design was applied to investigate the combined effect of two formulation variables - amounts of microcrystalline cellulose and mannitol. Results: The results of multiple regression analysis revealed that in order to obtain a fast dissolving tablet of the Aloe vera gel, an optimum concentration of mannitol and a higher content of microcrystalline cellulose should be used. A response surface plot was also provided to graphically represent the effect of the independent variables on the disintegration time and wetting time. The validity of the generated mathematical model was tested by preparing a check point batch. Conclusion: This investigation has demonstrated that satisfactory fast dissolving Aloe vera gel tablets can be formulated. It also showed the potential of experimental design in understanding the effect of formulation variables on the quality of fast dissolving tablets. Keywords: Aloe vera, Fast dissolving tablet, Factorial design, Mathematical model, Mannitol, Microcrystalline celluloseTropical Journal of Pharmaceutical Research Vol. 8 (1) 2009: pp. 63-7

Effect of vermicompost on manifestation of pesticide action on growth of Zinnia elegans

In order to asses the implication of endosulfan in the soil amended with vermicompost, Zinnia elegans (Family Asteraceae) was grown, under strict laboratory conditions. Seed germination, size of internode, total length of the plant, leaf area of the plant, tufts of rootlets, which emerged, were measured and recorded. Vermicompost at a concentration of 12.5% was used as source of amendment; treatment was made with endosulfan the concentration of which ranged from 2.5, 5 and 7.5% respectively. From the data obtained after 4 days of treatment, it appeared that the addition of endosulfan in plain soil (7.5%), affects germination to negative value. Reduced germination and plant growth even during prolonged treatment (up to 9 days) was noticed during treatment with 2.5 and 5% of endosulfan. In a soil amended with vermicompost, however, germination to total length of the plant was found to increase quite considerably. This trend has continued, even during extended period of treatment. The entire texture of the plant was found to change to a healthier look in the presence of vermicompost. Better growth of the plant, larger number of rootlets, and bigger leaf area, can be suggested to be additive role of vermicompost on growth and development of Zinnia elegans. This also indicated possible involvement of the plant in remediation of pesticide endosulfan. On this account, Z. elegans like related members of this family can be considered as a candidate involved in remediation of pesticides from polluted soilKey word: Vermicompost, endosulfan, Zinnia elegans

Graphene films printable on flexible substrates for sensor applications

Fifteen-layered graphene films have been successfully deposited onto flexible substrates using a commercial ink consisting of graphene particles dispersed in an acrylic polymer binder. A value of 74.9 × 105cm−2 was obtained for the density of defects, primarily located at the flake edges, from the ratio of the D and G Raman peaks located at 1345cm1 and 1575cm1 respectively. 0.5μm thick drop-cast films on interdigitated silver electrodes exhibited Ohmic conduction with a small activation energy of 12meV over the temperature range from 260K to 330K . The photo-thermoelectric effect is believed to be responsible for photoconduction through graphene films under illumination intensity of 10mWm-2 at 270 nm, corresponding to the UV absorption peak. The photo-transient decay at the bias of 1V involves two relaxation processes when the illumination is switched off and values of 8.9 × 103 and 4.3 × 104 are found for the relaxation time constant using the Kohlrauch stretched exponential function analysis.Dr. Indrani Banerjee is grateful to Commonwealth Association, UK for funding the present research work under the fellowship placement scheme (Grant reference INCF-2014-66). The studentship of Ms Faris is partially sponsored by the Air Force Office of Scientific Research, Air Force Material Command, USAF, under Grant No. FA9550-15-1-0123. We are also thankful to Miss V. M. Torrejon of Brunel University for support in computer graphics