A Reverse-Shock Model for the Early Afterglow of GRB 050525A

The prompt localization of gamma-ray burst (GRB) 050525A by {\em Swift} allowed the rapid follow-up of the afterglow. The observations revealed that the optical afterglow had a major rebrightening starting at $\sim 0.01$ days and ending at $\sim 0.03$ days, which was followed by an initial power-law decay. Here we show that this early emission feature can be interpreted as the reverse shock emission superposed by the forward shock emission in an interstellar medium environment. By fitting the observed data, we further constrain some parameters of the standard fireball-shock model: the initial Lorentz factor of the ejecta $\gamma_0>120$, the magnetic energy fraction $\epsilon_B>4\times10^{-6}$, and the medium density $n<2 {\rm cm^{-3}}$. These limits are consistent with those from the other very-early optical afterglows observed so far. In principle, a wind environment for GRB 050525A is disfavored.Comment: 11 pages, 1 figure, accepted for publication in Ap

Strategic Asset Seeking and Innovation Performance: The Role of Innovation Capabilities and Host Country Institutions

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An Improved NSGA-II and its Application for Reconfigurable Pixel Antenna Design

Based on the elitist non-dominated sorting genetic algorithm (NSGA-II) for multi-objective optimization problems, an improved scheme with self-adaptive crossover and mutation operators is proposed to obtain good optimization performance in this paper. The performance of the improved NSGA-II is demonstrated with a set of test functions and metrics taken from the standard literature on multi-objective optimization. Combined with the HFSS solver, one pixel antenna with reconfigurable radiation patterns, which can steer its beam into six different directions (θDOA = ± 15°, ± 30°, ± 50°) with a 5 % overlapping impedance bandwidth (S11 < − 10 dB) and a realized gain over 6 dB, is designed by the proposed self-adaptive NSGA-II

Gearbox fault diagnosis under different operating conditions based on time synchronous average and ensemble empirical mode decomposition

In this paper, a new method is proposed by combining ensemble empirical mode decomposition (EEMD) with order tracking techniques to analyse the vibration signals from a two stage helical gearbox. The method improves EEMD results in that it overcomes the potential deficiencies and achieves better order spectrum representation for fault diagnosis. Based on the analysis, a diagnostic feature is designed based on the order spectra of extracted IFMs for detection and separation of gearbox faults. Experimental results show this feature is sensitive to different fault severities and robust to the influences from operating conditions and remote sensor locations

Understanding occupancy pattern and improving building energy efficiency through Wi-Fi based indoor positioning

Detailed visualisation and data analysis of occupancy patterns including spatial distribution and temporal variations are of great importance to delivering energy efficient and productive buildings. An experimental study comprising 24-hour monitoring over 30 full days was conducted in a university library building. Occupancy profiles have been monitored and analysis has been carried out. Central to this monitoring study is the Wi-Fi based indoor positioning system based on the measured Wi-Fi devices’ number and locations and data mining methods. Distinct from traditional occupancy and energy studies, more detailed information related to the indoor positions and number of occupants has offered a better understanding of building user behaviour. The implication of the occupancy patterns for energy (e.g. lighting and other building services) efficiency is assessed, assisted with data from lighting sensors where needed. It is found occupancy patterns change dramatically with time. Also, the energy waste patterns have been identified through the method of data association rule mining. If the identified energy waste is removed, the total energy consumption can be reduced by 26.1%. The indoor positioning information also has implications for optimising space use, opening hours as well as staff deployment. The work could be extended to more rooms with diverse functions, other seasons and other types of non-domestic buildings for a more comprehensive understanding of building user behaviour and energy efficiency

Enhanced Magnetization from Proton Irradiated Bulk van der Waals Magnet CrSiTe3

Van der Waals (vdWs) crystals have attracted a great deal of scientific attention due to their interesting physical properties and widespread practical applications. Among all, CrSiTe3 (CST) is a ferromagnetic semiconductor with the Curie temperature (TC) of ~32 K. In this letter, we study the magnetic properties of bulk CST single-crystal upon proton irradiation with the fluence of 1x1018 protons/cm2. Most significantly, we observed an enhancement (23%) in the saturation magnetization from 3.9 {\mu}B to 4.8 {\mu}B and is accompanied by an increase in the coercive field (465-542 Oe) upon proton irradiation. Temperature-dependent X-band electron paramagnetic resonance measurements show no additional magnetically active defects/vacancies that are generated upon proton irradiation. The findings from X-ray photoelectron spectroscopy and Raman measurements lead us to believe that modification in the spin-lattice coupling and introduction of disorder could cause enhancement in saturation magnetization. This work demonstrates that proton irradiation is a feasible method in modifying the magnetic properties of vdWs crystals, which represents a significant step forward in designing future spintronic and magneto-electronic applications

Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: A case report

Background: Sixty mutations of claudin 16 coding gene have been reported in familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) patients. Recent investigations revealed that a highly conserved glycine-leucine-tryptophan (115G-L-W117) motif in the first extracellular segment (ESC1) of claudin 16 might be essential for stabilization of the appropriately folded ECS1 structure and conservation of normal claudin 16 function. However, neither missense nor nonsense mutation has ever been described in this motif. Our study aimed at identifying mutations in a Chinese patient with FHHNC and exploring the association between genotype and phenotype. Case presentation: A 33-year-old female presented with 4 years history of recurrent acute pyelonephritis without other notable past medical history. Her healthy parents, who aged 56 and 53 respectively, were second cousins, and her only sibling died from renal failure without definite cause at age 25. Renal ultrasound imaging demonstrated atrophic kidneys and bilateral nephrocalcinosis. The laboratory workup revealed impaired renal function (Stage CKD IV), hypocalcemia and mild hypomagnesemia, accompanied with marked renal loss of magnesium and hypercalciuria. During the follow-up, treatment with calcitriol and calcium but not with magnesium was difficult to achieve normal serum calcium levels, whereas her serum magnesium concentration fluctuated within normal ranges. In the end, the patient unavoidably reached ESRD at 36 years old. The clinical features and family history suggested the diagnosis of FHHNC. To make a definite diagnosis, we use whole-exome sequencing to identify the disease-causing mutations and Sanger sequencing to confirm the mutation co-segregation in the family. As a result, a novel homozygous mutation (c.346C > G, p.Leu116Val) in115G-L-W117motif of claudin 16 was identified. Her parents, grandmother and one of her cousins carried heterozygous p.Leu116Val, whereas 200 unrelated controls did not carry this mutation. Conclusions: We described a delayed diagnosis patient with FHHNC in the Chinese population and identified a novel missense mutation in the highly conserved115G-L-W117motif of claudin 16 for the first time. According to the reported data and the information deduced from 3D modeling, we speculate that this mutation probably reserve partial residual function which might be related to the slight phenotype of the patient