1,460 research outputs found

    Giant dipole resonance with exact treatment of thermal fluctuations

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    The shape fluctuations due to thermal effects in the giant dipole resonance (GDR) observables are calculated using the exact free energies evaluated at fixed spin and temperature. The results obtained are compared with Landau theory calculations done by parameterizing the free energy. The Landau theory is found to be insufficient when the shell effects are dominating.Comment: 5 pages, 2 figure

    FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF LEVOSULPIRIDE BY USING NATURAL POLYMER

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    Objective: The objective of the present study was to develop sustained release matrix tablets of levosulpiride by using natural polymers.Method: The tablets were prepared with different ratios of Chitosan, Xanthan gum and Guar gum by wet granulation technique. The solubility study of the levosulpiride was conducted to select a suitable dissolution media for in vitro drug release studies.Results: Fourier transform infrared (FTIR) study revealed no considerable changes in IR peak of levosulpiride and hence no interaction between drug and the excipients. DSC thermograms showed that no drug interaction occurred during the manufacturing process. In vitro dissolution study was carried out for all the formulation and the results compared with marketed sustained release tablet. The drug release from matrix tablets was found to decrease with increase in polymer ratio of Chitosan, Xanthan gum and Guar gum.Conclusion: Formulation LF3 exhibited almost similar drug release profile in dissolution media as that of marketed tablets. From the results of dissolution data fitted to various drug release kinetic equations, it was observed that highest correlation was found for First order, Higuchi's and Korsmeyer equation, which indicate that the drug release occurred via diffusion mechanism.    Â

    Applicability of shape parameterizations for giant dipole resonance in warm and rapidly rotating nuclei

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    We investigate how well the shape parameterizations are applicable for studying the giant dipole resonance (GDR) in nuclei, in the low temperature and/or high spin regime. The shape fluctuations due to thermal effects in the GDR observables are calculated using the actual free energies evaluated at fixed spin and temperature. The results obtained are compared with Landau theory calculations done by parameterizing the free energy. We exemplify that the Landau theory could be inadequate where shell effects are dominating. This discrepancy at low temperatures and high spins are well reflected in GDR observables and hence insists on exact calculations in such cases.Comment: 10 pages, 2 figure

    Experimental culture of prawns and fishes in coastal pens at Tuticorin during 1976-'78

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    The paper gives an account of experimental culture of prawns, Penaeus semisulcatus, P. indicus and fishes Chanos chanos and Mugil in split bamboo screen pens, constructed in the shallow bay at Tuticorin during 1976-'78

    Optimal process for the extraction and identification of flavonoids from the leaves of Polyalthia longifolia using L16 Orthogonal design of experiment

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    The study has been carried out to investigate the effects of single factors such as temperature, extraction time, concentration of ethanol, material ratio and no. of extractions on the contents of flavonoids present in the leaves of Polyalthia longifolia. On this basis, an L16 orthogonal design of experiment was used to determine the optimal conditions for the extraction of flavonoids. The amount of flavonoids extracted reached its maxima at 65 ºC for 2 hrs by using 75% ethanol (modifier) with a material ratio of 1:10 and 2 times ofextraction. The TLC performed for the optimal extracts showed the presence of rutin and quercetin related compounds.Keywords: Annonaceae, Flavonoids, Orthogonal experiments, Single-factor experiments, Polyalthia longifolia

    On the fishery for the crab Scylla serrata (Forskal) At Tuticorin during 1974-75

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    Scylla serrata occurs in fairly good numbers at Tuticorin, throughout the year. In the nortbsrn part, it is usually caught from the shallow coastal waters by shore-seines and cast-nets, while in the backwaters and canals of the southern region by a simple trapping device. Apart from these, certain drag-nets, stakenets, baited hooks and hand-picking are also resorted to for the capture of this crab. The estimated yield of S. serrata during 1974-75 was 9,460.6 kg, of wthich 53.7% were 'by nets and 46.3% by traps. The combined annual size-frequency distribution of the orate has indicated the presence of three distinct age-groups, with modes at 11-5, 155 and 185/195 mm. Gross examination of gowadial conditions has shown three stages of maturity for both sexes, representing immature, maturing and mature conditions. Berried females Showed two stages in the development of eggs. It appears that for improving the quality and quantity of the catches, the smallest size groups with dominant mode at 115 mm carapace width could be spared from the efforts of the fishery

    False-positive troponin elevation due to an immunoglobulin-G-cardiac troponin T complex: a case report.

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    Background: Troponin is a crucial biomarker for the diagnosis of an acute coronary syndrome (ACS). It rises in response to myocardial injury from significant acute myocardial ischaemia caused by obstructive coronary artery disease ['classical' myocardial infarction (MI)]. However, raised levels have also been noted in conditions not recognized as classical ACS. This may include MI with non-obstructed coronary arteries such as takotsubo cardiomyopathy and other acute or chronic conditions such as pulmonary embolus or chronic kidney disease. This is commonly labelled as a 'falsely elevated' troponin although there is some myocardial strain to explain the rise, such as an increase in cardiac oxygen demand. True 'falsely elevated' troponin, characterized by a persistent elevation in the absence of cardiac injury does occur and thought to be secondary to an immunoglobulin-troponin complex (macrotroponin). Case summary: A 53-year-old gentleman with a background of diabetes, hypertension, hypercholesterolaemia, and hepatitis B was admitted with chest pain and persistently elevated cardiac troponin T (cTnT) levels. Investigations revealed unobstructed coronary arteries and a structurally normal, well-functioning heart. Subsequent biochemical analysis found the persistently elevated cTnT secondary to macrotroponin T. Discussion: Macrotroponin, an immunoglobulin-troponin bound complex should be considered as a differential diagnosis when the biochemistry is not reflective of the clinical picture. Early recognition requires effective collaboration with the biochemistry laboratory for accurate diagnosis

    Industrial fisheries off Saurashtra coast based on exploratory survey during 1985-'88

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    In Saurashtra waters, where fishery resource is currently being well exploited by private sector, exploratory survey programmes are being conducted by Government of India. The analysis, based on 4 year survey (1985-'88), with a view to provide information and to extend our knowledge about the spatial and seasonal distribution of various industrially important fishes along the Saurashtra coast. Ribbon fish and sciaenids which constituted the bulk of the catch together formed more than 60% of the total catch and catch rate were 14.7 and 14.5 kg/hr respectively. Area-wise analysis of data revealed that maximum effort was expended in 21° 69 0 and the effort was very low in 21° 70° and 23° 68° Depth wise analysis revealed that the maximum catch rate of ribbon fish and other sciaenids was obtained at 21-30 m depth. The catch rate of elasmobranch, carangid and Lactarius lactarius was maximum at 41-50 m, cat fish, pomfret and perch at 51-60 m and carangid and cephalopod at 61-70 m depth
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