792 research outputs found

    Thailand\u27s Board of Investment: Towards a More Appropriate and Effective Rural Investment Promotion Policy

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    This Comment analyzes the role of Thailand\u27s Board of Investment in the Thai Government\u27s policy of decentralizing its economy. The Board of Investment is the administrative agency authorized to promote industrial development through the use of investment incentives. In response to the decentralization policy, the Board has created new categories of investment and a new set of upgraded incentives designed to encourage industrial investment in the country\u27s rural provinces. The potential effectiveness of the Board\u27s role, however, is limited. Recent changes in Thailand\u27s tax and trade policy have seriously diminished the value of the Board\u27s fiscal incentives, the backbone of its incentive scheme. The Board must overcome significant barriers to investment in rural areas, namely inadequate infrastructure and shortages of skilled labor. Moreover, fiscal incentives have numerous drawbacks, and evidence suggests that they are limited in their ability to attract investment. Thus, the Investment Promotion Act, the controlling legislation for the Board of Investment, should be amended to replace the fiscal incentives with new types of incentives which are both attractive to investors and have greater potential to benefit Thailand\u27s rural areas

    Can molecular cell biology explain chromosome motions?

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    <p>Abstract</p> <p>Background</p> <p>Mitotic chromosome motions have recently been correlated with electrostatic forces, but a lingering "molecular cell biology" paradigm persists, proposing binding and release proteins or molecular geometries for force generation.</p> <p>Results</p> <p>Pole-facing kinetochore plates manifest positive charges and interact with negatively charged microtubule ends providing the motive force for poleward chromosome motions by classical electrostatics. This conceptual scheme explains dynamic tracking/coupling of kinetochores to microtubules and the simultaneous depolymerization of kinetochore microtubules as poleward force is generated.</p> <p>Conclusion</p> <p>We question here why cells would prefer complex molecular mechanisms to move chromosomes when direct electrostatic interactions between known bound charge distributions can accomplish the same task much more simply.</p

    Factors affecting velvet antler weights in free-ranging reindeer in Alaska

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    Free-ranging reindeer on the Seward Peninsula in western Alaska are rounded up from late May to early July and antlers are removed. We used data collected from 1987 to 1997 to determine how velvet antler weights of males and females varied with age, year, reproductive status, Julian date, and body weight. Male antler weights increased with age up to age five years, and were lower in castrates than in bulls. There was a significant positive relationship between body weight and antler weight in both sexes. Female antler weights increased with age until at least age nine. Lactating females had lower antler weights than non-lactating females, but this effect is better explained by differences in body weight. Antler weight of individual reindeer at age two years was better predicted by their antler weights as yearlings than their body weight as yearlings

    Lactation in yearling Alaskan reindeer: Implications for growth, reproduction, and survival

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    Unlike most Rangifer herds, free-ranging female reindeer {Rangifer tarandus) on the Seward Peninsula, Alaska frequently give birth as yearlings (12 months). In other reindeer herds this early reproduction has led to negative effects such as decreased future weight gain and reproduction. We analyzed reindeer data collected on the Seward Peninsula between 1987 and 1997 to determine what effect lactating as yearlings had on future weight gain, reproductive rates, and survival. Reindeer were rounded up during June and early July. Individual ear tag numbers were recorded, females were visually inspected for the presence of a distended udder, and some animals were weighed. Females with distended udders as yearlings had subsequent recapture rates, survival rates, weight gain, and future reproductive success comparable to females that did not have distended udders as yearlings. These findings suggest that the beneficial effects of increased calf weight gain outweigh potential negative effects of early reproduction in these reindeer. This may be due to high quality range leading to heavy calves and the ability of females to maintain body reserves during lactation

    Back Pay in Employment Discrimination Cases

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    This Special Project examines the back pay decisions and analyzes the problems that have confronted the courts dealing with this remedy for employment discrimination in the context of Title VII and section 1981. Because of the enormity of the issues that have arisen in Stage I of the proceedings, however, and the extensive coverage given those problems by the courts and commentators, the Special Project will deal only with the recovery stage, or Stage II, of the litigation. Consequently, the reader should assume that liability for employment discrimination has already been established in each of the cases discussed below. Before reaching the various procedural and substantive issues surrounding back pay awards, however, the Project, in part II, presents an over-view of the statutory authority for back pay including the legislative history of Title VII and section 1981. Part II also discusses the development of the appropriate standard for the exercise of judicial discretion in awarding back pay. Part III examines the parties liable for the payment of back pay. In part IV the Project explores presumptive eligibility for back pay and in part V considers possible grounds on which a defendant may seek to rebut the presumption. Parts VI and VII discuss the proof-of-claim procedure that must be followed by discriminatees claiming back pay and the procedure for determining individual awards. Part VIII then identifies and analyzes the various problems facing courts in allocating the burdens of proof that plaintiffs and defendants must meet before the court can determine individual awards. Following the discussion of the order and allocation of the burdens of proof, part IX outlines the various methods used by the courts to compute individual back pay awards and also discusses other issues such as the elements includable and deductible, the mitigation requirement,and the limitation periods for back pay. In part X the Special Project examines the problems that may arise when the parties agree to a settlement of back pay claims

    Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin

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    Actively transcribed regions of the genome are vulnerable to genomic instability. Recently, it was discovered that transcription is repressed in response to neighboring DNA double-strand breaks (DSBs). It is not known whether a failure to silence transcription flanking DSBs has any impact on DNA repair efficiency or whether chromatin remodelers contribute to the process. Here, we show that the PBAF remodeling complex is important for DSB-induced transcriptional silencing and promotes repair of a subset of DNA DSBs at early time points, which can be rescued by inhibiting transcription globally. An ATM phosphorylation site on BAF180, a PBAF subunit, is required for both processes. Furthermore, we find that subunits of the PRC1 and PRC2 polycomb group complexes are similarly required for DSB-induced silencing and promoting repair. Cancer-associated BAF180 mutants are unable to restore these functions, suggesting PBAF's role in repressing transcription near DSBs may contribute to its tumor suppressor activity

    Earthquakes, cancer and cultures of fear: qualifying as a Skills for Life teacher in an uncertain economic climate

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    The Skills for Life (SfL) initiative followed the Moser Report (1999) and incarnated a Third Way agenda that sought to address England's perceived adult skills deficit. SfL marked a large investment in adult education but also a distinct shift to a more focused, instrumentalist role for Further Education (FE) in England. A new structure of teacher standards and qualifications underpinned this development with its own, newly devised and matriculated knowledge base. Teachers emerged from these new programmes with subject specialisms in Literacy, Numeracy and English for Speakers of Other Languages (ESOL). The landscape that these ‘new professionals' have entered is one that suggests the autonomy of colleges within a competitive market, but this disguises a funding methodology that facilitates ongoing centralised policy intervention. In the last two years policy makers have used this funding methodology to shift monies decisively towards 14-19 provision and away from adult education. This article draws on qualitative data from a study into the experiences of pre and in-service SfL teachers in the final stages of qualification. The data explore the impact of these latest movements in the FE market on these student teachers who are qualifying in some of the newest subjects in FE

    Instruments to measure the ability to self-reflect:A systematic review of evidence from workplace and educational settings including health care

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    Introduction: Self-reflection has become recognised as a core skill in dental education, although the ability to self-reflect is valued and measured within several professions. This review appraises the evidence for instruments available to measure the self-reflective ability of adults studying or working within any setting, not just health care. Materials and Methods: A systematic review was conducted of 20 electronic databases (including Medline, ERIC, CINAHL and Business Source Complete) from 1975 to 2017, supplemented by citation searches. Data were extracted from each study and the studies graded against quality indicators by at least two independent reviewers, using a coding sheet. Reviewers completed a utility analysis of the assessment instruments described within included studies, appraising their reported reliability, validity, educational impact, acceptability and cost. Results: A total of 131 studies met the inclusion criteria. Eighteen were judged to provide higher quality evidence for the review and three broad types of instrument were identified, namely: rubrics (or scoring guides), self-reported scales and observed behaviour. Conclusions: Three types of instrument were identified to assess the ability to self-reflect. It was not possible to recommend a single most effective instrument due to under reporting of the criteria necessary for a full utility analysis of each. The use of more than one instrument may therefore be appropriate dependent on the acceptability to the faculty, assessor, student and cost. Future research should report on the utility of assessment instruments and provide guidance on what constitutes thresholds of acceptable or unacceptable ability to self-reflect, and how this should be managed

    Diasporic Security and Jewish Identity

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    This paper explores the relationship between identity and security through an investigation into Jewish diasporic identity. The paper argues that the convention of treating identity as an objective referent of security is problematic, as the Jewish diaspora experience demonstrates. The paper presents a new way of conceptualizing identity and security by introducing the concept of diasporic security. Diasporic security reflects the geographical experience of being a member of a trans-state community, of having a fluid identity that is shaped by sometimes contradictory discourses emanating from a community that resides both at home and abroad. In introducing the concept of diasporic security, the paper makes use of literature in Diaspora Studies, Security Studies, recent works in contemporary political theory and sociology, and Woody Allen's film, Deconstructing Harry (1997)
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