A comparison of methods to evaluate energy expenditure of incubating wandering albatrosses

Measurements of incubation energetics can vary depending on the method used to measure metabolism of an incubating bird. Therefore, we evaluated the energy expenditure of six male and four female wandering albatrosses (Diomedea exulans Linnaeus) using doubly labeled water (DLW), the rate of mass loss, and estimates of metabolic water production derived from water influx rate (WIR). Incubation metabolic rates (IMR) determined with DLW ( 169 ± 21 kJ kg d SD) were significantly lower than estimates derived from mass loss ( 277 ± 46kJ kg d SD) and WIR ( males=289 ± 60 kJ kg d vs. females = 400 ± 69 kJ kg d SD). Estimates of IMR from f WIR were similar to IMR (305 ± 39 kJ kg d SD) determined by respirometry in a previous study, and IMR from DLW was similar to estimates based on heart rate (HR; 147 ± 26 kJ d SD) determined in another study. Ap- 147 26 plying the different measurements of IMR to construct an en-ergy budget, we estimate that a breeding pair of wandering albatrosses spends 124--234 MJ to incubate the egg for 78 d. Finally, IMRs determined with DLW and HR were similar

The use of the sedimentation test to the clinician in the prognosis and treatment of pulmonary tuberculosis

I. There is a definite need for a reliable test to guide the clinician in dealing with the problem of pulmonary tuberculosis. II. The sedimentation of the erythrocytes in blood plasma is increased in conditions in which there is an increase of the fibrinogen and serum -globulin contents of the blood. This occurs in diseases associated with toxaemia and tissue destruction. III. The sedimentation rate is an index of the amount of toxaemia present, and this in pulmonary tuberculosis infers the degree of activity and powers of resistance. IV. The "one hour" reading of the sedimentation test in millimetres percent conveys most information to the clinician and is compatible with clinical experience. V. The sedimentation test lacks specificity and hence is of limited value in the diagnosis of pulmonary tuberculosis; an abnormal rate does however indicate that a lesion is active and the extent. VI. A series of tests, performed at intervals over a period of several months, affords valuable data upon which a prognosis may be based. Further it gives information concerning the powers of resistance present, and enables the clinician to judge the amount and rate of progress. VII. The sedimentation test is not only more sensitive than clinical findings in indicating the amount of toxaemia but also in prophesying ensuing complications, save in haemoptysis due to rupture of the Rasmussen type of aneurysm. VIII. The test excels as a means of regulating routine sanatorium treatment. It also evidences the need of instituting additional forms of treatment and depicts further progress. IX. When a maintained normal sedimentation test, in a patient that has been definitely active at some time, conflicts with the continued presence of tubercle bacilli in the sputum or some other single sign of activity, the whole clinical picture and rate must be viewed in relation to each other and the case kept under observation for many months before quiescence and inactivity are definitely considered. X. In a certain number of patients a rising sedimentation rate does not coincide with the definite clinical progress present; further observation will reveal some outside influence

Recreating the Past: Aachen and the Problem of the Architectural "Copy"

This thesis explores the formal, historiographic and critical issues of similitude and the problem of historical memory through Charlemagne's chapel at Aachen and buildings associated with it. In my study, I seek to understand some of the levels on which reference to and appropriation of Aachen reflect the historical, political and cultural moment unique to each of five selected interpretations and how, in these examples, the perception of Aachen provided an image through which contemporary concerns ad meanings could be expressed. The issue, therefore, is not so much what Aachen was like, physically or even ideologically, at the time it was built, but how the chapel was perceived in later times, and, importantly, what the terms of that image were and how that image made the chapel a viable touchstone for later references - often ambiguously termed "copies." These buildings can be seen not simply as subordinate to Aachen, but as works that incorporate an image of Aachen for their own ends; through this incorporation, Aachen can be seen as actually subject to them for its own survival. My study raises the question of what it can mean to remember Aachen and the corollary issue of what it can mean to be like Aachen. My chosen examples underscore that while the chapel remained a potent image, the perception of Aachen as a work of the past as well as the criteria for likeness are changeable and tied to time and circumstance

Corticosterone and foraging behaviour in a pelagic seabird

Because endocrine mechanisms are thought to mediate behavioral responses to changes in the environment, examining these mechanisms is essential for understanding how long-lived seabirds adjust their foraging decisions to contrasting environmental conditions in order to maximize their fitness. In this context, the hormone corticosterone (CORT) deserves specific attention because of its major connections with locomotor activities. We examined for the first time the relationships between individual CORT levels and measurements of foraging success and behavior using satellite tracking and blood sampling from wandering albatrosses (Diomedea exulans) before (pretrip CORT levels) and after (posttrip CORT levels) foraging trips during the incubation period. Plasma CORT levels decreased after a foraging trip, and the level of posttrip CORT was negatively correlated with individual foraging success, calculated as total mass gain over a foraging trip. Pretrip CORT levels were not linked to time spent at sea but were positively correlated with daily distance traveled and maximum range at sea. In this study, we were able to highlight the sensitivity of CORT levels to variation in energy intake, and we showed for the first time that individual CORT levels can be explained by variation in foraging success. Relationships between pretrip CORT levels and daily distance traveled and maximum range were independent of pretrip body mass, suggesting that slight elevations in pretrip CORT levels might facilitate locomotor activity. However, because both foraging behavior and pretrip CORT levels could be affected by individual quality, future experimental studies including manipulation of CORT levels are needed to test whether CORT can mediate foraging decisions according to foraging conditions

Effects of systematic errors on the mixing ratios of trace gases obtained from occulation spectra

The influence of systematic errors in the parameters of the models describing the geometry and the atmosphere on the profiles of trace gases retrieved from simulated solar occultation spectra, collected at satellite altitudes, is investigated. Because of smearing effects and other uncertainties, it may be preferable to calibrate the spectra internally by measuring absorption lines of an atmospheric gas such as CO2 whose vertical distribution is assumed rather than to relay on externally supplied information

Lung Rest During Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure-Practice Variations and Outcomes.

OBJECTIVE: Describe practice variations in ventilator strategies used for lung rest during extracorporeal membrane oxygenation for respiratory failure in neonates, and assess the potential impact of various lung rest strategies on the duration of extracorporeal membrane oxygenation and the duration of mechanical ventilation after decannulation. DATA SOURCES: Retrospective cohort analysis from the Extracorporeal Life Support Organization registry database during the years 2008-2013. STUDY SELECTION: All extracorporeal membrane oxygenation runs for infants less than or equal to 30 days of life for pulmonary reasons were included. DATA EXTRACTION: Ventilator type and ventilator settings used for lung rest at 24 hours after extracorporeal membrane oxygenation initiation were obtained. DATA SYNTHESIS: A total of 3,040 cases met inclusion criteria. Conventional mechanical ventilation was used for lung rest in 88% of cases and high frequency ventilation was used in 12%. In the conventional mechanical ventilation group, 32% used positive end-expiratory pressure strategy of 4-6 cm H2O (low), 22% used 7-9 cm H2O (mid), and 43% used 10-12 cm H2O (high). High frequency ventilation was associated with an increased mean (SEM) hours of extracorporeal membrane oxygenation (150.2 [0.05] vs 125 [0.02]; p \u3c 0.001) and an increased mean (SEM) hours of mechanical ventilation after decannulation (135 [0.09] vs 100.2 [0.03]; p = 0.002), compared with conventional mechanical ventilation among survivors. Within the conventional mechanical ventilation group, use of higher positive end-expiratory pressure was associated with a decreased mean (SEM) hours of extracorporeal membrane oxygenation (high vs low: 136 [1.06] vs 156 [1.06], p = 0.001; mid vs low: 141 [1.06] vs 156 [1.06]; p = 0.04) but increased duration of mechanical ventilation after decannulation in the high positive end-expiratory pressure group compared with low positive end-expiratory pressure (p = 0.04) among survivors. CONCLUSIONS: Wide practice variation exists with regard to ventilator settings used for lung rest during neonatal respiratory extracorporeal membrane oxygenation. Use of high frequency ventilation when compared with conventional mechanical ventilation and use of low positive end-expiratory pressure strategy when compared with mid positive end-expiratory pressure and high positive end-expiratory pressure strategy is associated with longer duration of extracorporeal membrane oxygenation. Further research to provide evidence to drive optimization of pulmonary management during neonatal respiratory extracorporeal membrane oxygenation is warranted