ANKARA MİLLİ KÜTÜPHANESİ NEVŞEHİRLİ DAMAD İBRAHİM PAŞA KOLEKSİYONUNDAKİ 50_DAMAD_7 ENVANTER NUMARALI KURAN-I KERİMİN TEZHİP SANATI AÇISINDAN DEĞERLENDİRİLMESİ .

ÖZET Adnan Ötüken tarafından Milli Eğitim Bakanlığı’na bağlı olarak 1946 yılında kurulan Milli Kütüphane, günümüzde birçok eser barındırmaktadır. Milli Kütüphane bünyesinde bulunan yazma eserlerden 50_DAMAD_7 Envanter numaralı Kuran-ı Kerim tezyinatı bakımından incelenmek için seçilmiştir. Yapılan bu çalışmada Millî Kütüphane’ de diğer yazmalar bölümünde Damad İbrahim Paşa Koleksiyonunda bulunan yazma eserler, tarama yöntemi ile tespit edilmiş ve bu eser süsleme, üslup özellikleri açısından değerlendirilerek eserin künye bilgilerinin yanı sıra, tezyinat özellikleri hakkında bilgi verilmiştir. Millî Kütüphane ’de el yazmaları bölümünde 27.121 adet eser mevcut olup, Damad koleksiyonunda bulunan 592 yazma eserlerden envanter numarası 50_DAMAD_7, olan Kuran-ı Kerimin, zahriye, serlevha, sure başı, duraklar, sayfa kenarı gülleri, koltuk tezhibi ve hatime sayfalarının tezyinatı, motif, desen ve üslup özellikleri detaylı incelenerek çizimleri yapılmış, desen ve üslup bakımından dönemine aidiyeti hakkında yorum yapılmıştır

Benign solitary pulmonary necrotic nodules: How effectively does pathological examination explain the cause?

Aims. We investigated the histopathological features of solitary pulmonary necrotic nodules (NNs) of undetermined cause. We combined our findings with those obtained using other methods to determine how well the etiological factors were explained.Methods. We screened patients who underwent surgery to treat solitary pulmonary granulomatous and nongranulomatous NNs of undetermined cause. The NN sizes and features of both the NNs and adjacent parenchyma were evaluated. Histochemical analyses included Ehrlich-Ziehl-Neelsen (EZN), Grocott, and Gram staining. Polymerase chain reaction (PCR) was used to detect tuberculous and nontuberculous mycobacteria, panfungal DNA,Nocardia,Francisella tularensistypes A and B, and actinomycetes.Results. The NNs were granulomatous in 78.9% and nongranulomatous in 21% of the 114 patients included. EZN staining or PCR was positive forMycobacteriumin 53.5% of all NNs: 62.2% of granulomatous and 20.8% of nongranulomatous NNs. We found a weak but significant correlation between granulomatous NNs andBacilluspositivity and a significant correlation between granulomas surrounding the NNs and the presence of multiple necroses. The NN etiology was determined via histopathological, histochemical, and PCR analyses in 57% of patients but remained undetermined in 42.9%.Conclusion. The causes of both granulomatous and nongranulomatous NNs can be determined by pathological examination. Granulomatous necrosis and granulomas in the adjacent parenchyma are important for differential diagnosis. When both features are present, they strongly support a diagnosis of tuberculosis, even in the absence of bacilli

LWE: An Energy-Efficient Lightweight Encryption Algorithm for Medical Sensors and IoT Devices

In today's world, systems generate and exchange digital data frequently and face a much broader range of threats than in the past. Within the context of this unsafe ecosystem, it is crucial to protect the data in a quick and secure way. In this paper, it is proposed that a lightweight block cipher algorithm called LWE in the purpose of having an encryption algorithm that is light enough for restricted/limited hardware environments and secure enough to endure primal cryptanalysis attacks. The length of blocks to be encrypted is set to 64 bits and the key length is defined as 64 bits. It is targeted for IoT systems with low-end microcontrollers and body sensor area devices. The performance and security aspects of LWE are evaluated with well-known algorithms and it is observed that LWE can establish a basic security baseline for transmitting raw data without creating a heavy load on the network infrastructure

Prevalence of Sleep Disordered Breathing Symptoms and Their Relation with Concomitant Diseases in Afyon, Turkey: A Population Based Study

Objective: To estimate the prevalence of symptoms of sleep-disordered breathing (SDB) and to evaluate the relationship between these symptoms and concomitant systemic disorders in Turkish adults. Material and Methods: A sample group representing whole Afyon city filled, a questionnaire consisting of questions about demographic features, SDB symptoms and concomitant diseases. Body mass indices of the subjects were calculated. Results: There was no significant difference for snoring between males and females, whereas witnessed apnea and excessive daytime sleepiness were significantly higher in females. Obesity was more prevalent among females. SDB symptoms were more common among obese subjects. Diabetes (DM), hypertension (HT), hyperlipidemia and congestive heart failure (CHF) were significantly more prevalent among snorers. There was a 1.7 folds increase in HT risk and a 1.4 folds increase in DM risk in snorers. We also found a 1.4 folds increased risk for hyperlipidemia and 2.1 folds increased risk for CHF in our snorer population. Snoring and witnessed apnea were found as risk factors for hypertension independently from smoking status. BMI and age. Conclusion: The frequency of SDB symptoms were high in Afyon city, with a greater than expected rate for females. Snoring and witnessed apnea were found as independent risk factors for hypertension

Health profiles of methyl bromide applicators in greenhouses in Turkey.

Introduction: Methyl bromide is a toxic substance that has hazardous effects on human health with acute and chronic exposure. Our previous study showed that methyl bromide applicators frequently use large amounts of methyl bromide haphazardly in greenhouses in the prefectures of Narlidere and Balcova in the Aegean city of Izmir. This study aims to evaluate the health conditions of these workers. Materials and Methods: Our previous study showed that there are 38 methyl bromide applicators in our study area. After the informed consent of methyl bromide applicators was obtained, a questionnaire was used for a survey of demography and symptoms. Each subject was examined before and after application of the compound. Blood and urine samples were collected and stored. Blood samples were analysed for methyl bromide and bromide ion, kidney and liver function tests and lipid profile. Results: The age range of subjects was 19 to 53 years (mean age: 41 +/- 8.57). This study showed that methyl bromide applicators use large amounts of methyl bromide disregarding legal regulations and that some of them had nonspecific complaints. Subjects had been working as methyl bromide applicators for approximately 9.7 +/- 4.15 years. A total of 69.7% of methyl bromide applicators reported that they did not use protective equipment while 33.3% of them had a history of acute methyl bromide intoxication. A statistically significant relationship was found between the usage of protective equipment and the level of blood bromide ion in the blood (P<0.05). Conclusion: Usage of methyl bromide, training, screening and follow-up of applicators must be rigorously controlled in accordance with national legal arrangements and international protocols. Greater efforts are required in the implementation of controls to achieve the targets set by the legal regulations and to ensure continual improvement in the limitation of the risks of this environmental hazard

Management of Polydrug-Resistant Tuberculosis

Background and Objectives: There is a lack of information regarding the effective duration of treatment necessary to prevent the development of acquired resistance when fluoroquinolones (FQ), and/or pyrazinamide (Z) resistance has occurred in patients with polydrug-resistant tuberculosis and isoniazid resistance. The management of these kinds of patients should be carried out in experienced centers according to drug susceptibility test results, clinical status of the patient and the extensity of the disease. Materials and Methods: We evaluated treatment regimens, treatment outcomes, and drug adverse effects in seven patients with polydrug-resistant tuberculosis, including those with Z and/or FQ resistance in a retrospective analysis Results: Regarding the patients with polydrug-resistant tuberculosis in addition to isoniazid (H) resistance, three had Z, two had FQ, and the remaining two had both Z and FQ resistance. In the intensive phase of the treatment, the patients were given at least four drugs according to drug susceptibility tests, and at least three drugs in the continuation phase. The duration of treatment was 9–12 months. Two of the patients were foreign nationals, and could not be followed up with due to returning to their home countries. Regarding the remaining five patients, three of them were terminated as they completed treatment, and two as cured. No recurrence was observed in the first year of the treatment. The most common, and serious drug side effect was seen for amikacin. Conclusions: In patients with polydrug-resistant TB, if Z and/or FQ resistance is detected in addition to H resistance, the treatment of these patients should be conducted on a case-by-case basis, taking into account the patient’s resistance pattern, clinical condition, and disease prognosis. Close monitoring of the side effects will increase the success rate of the treatment