Levels of anxiety and depression as predictors of mortality following myocardial infarction: A 5-year follow-up

Background: Post-myocardial infarction (MI) depression is a highly prevalent disorder, affec­ting nearly 18% of all MI patients, and it is a major predictor of disability in the year post-MI. We sought to expand this analysis by: comparing case-level anxiety, depression, and comorbid anxiety and depression as predictors of long term mortality during a 5-year follow-up period after MI; and investigating the role of potential modifying and confounding factors. Methods: A total of 285 patients were screened on average 6 days after their MI and a 5-year survival rate was ascertained. The Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI) were completed by patients hospitalized for MI. In addition we tested the BDI × STAI interaction effect. Results: During the 5 years of follow-up, cardiac mortality was assessed in 274 of 285 eligible patients. Of the 274 patients whose survival data were available, 91 (33.2%) died. At entry, BDI score of 192 (67.4%) patients was ≥ 10 and 145 (50.9%) patients had STAI score ≥ 40. Anxiety was not associated with mortality, whereas depression significantly predicted death, but this association was attenuated to non-significance with full adjustment with disease severity and confounders. Conclusions: Depression following MI does not predict longer-term survival with full adjustment.

Comparing the effectiveness of music therapy and alpha-theta neuro-feedback training on anxiety and depression among patients with chronic irritable bowel syndrome

BACKGROUND: Non-pharmaceutical interventions are a promising area of research in psychiatry. Traditional treatment of Irritable Bowel Syndrome (IBS) lacked notable efficacy. The aim of this study was to examine the effectiveness of music therapy (MT) and alpha-theta neurofeedback training (NFT) on anxiety and depression symptoms among patients with IBS.METHODS: Patients with IBS, based on ROME III criteria, and high level of anxiety or depression symptoms were randomly assigned into three groups: (A) music, (B) alpha-theta training, and (C) control. In intervention groups, participants received ten 30-minute sessions of either music or alpha-theta NFT. The Hospital Anxiety and Depression Scale (HADS) was administered for all patients before and after the training period. Thirty-three patients completed the study. Data were analyzed using analysis of covariance (ANCOVA) to compare changes in HADS scores among the three study groups.RESULTS: There was a significant main effect of HADS scores (F1,18 = 17.79, P < 0.001) in the responses of MT group. Significant decreases were observed in HADS scores from pre-intervention to post-intervention tests in MT group comparing to control group. The MT accounted for 49 percent of variance in HADS scores. There was also a significant main effect of HADS scores (F1,20 = 17.79, P < 0.010) in the responses of NFT group. HADS scores from pre-intervention to post-intervention tests in alpha-theta NFT group comparing to control group showed significant decreases, too. In addition, MT and alpha-theta NFT did not show any significant difference in somatic symptoms scores between pretest and posttest among patients with IBS.CONCLUSION: This study showed that MT and alpha-theta NFT significantly alleviated anxiety and depression level among patients with IBS

Suppression of Obsessive-Compulsive Symptoms after Head Trauma

Obsessive-Compulsive Disorder (OCD) encompasses a spectrum of clinical symptoms characterized by unwanted thoughts coupled with an intense compulsion to act and to repeat behavior fragments in a ritualistic and stereotyped sequence. Obsessive-compulsive symptom due to brain lesions is not rare, but suppression of these symptoms after head trauma is very rare and we found only 3 cases in review of literatures from 1966 to 2001. The case of a patient suffering with severe OCD is described of note; her symptoms disappeared following right temporo-parietofrontal lesion

Comparing the effectiveness of music therapy and alpha-theta neuro-feedback training on anxiety and depression among patients with chronic irritable bowel syndrome

BACKGROUND: Non-pharmaceutical interventions are a promising area of research in psychiatry. Traditional treatment of Irritable Bowel Syndrome (IBS) lacked notable efficacy. The aim of this study was to examine the effectiveness of music therapy (MT) and alpha-theta neurofeedback training (NFT) on anxiety and depression symptoms among patients with IBS. METHODS: Patients with IBS, based on ROME III criteria, and high level of anxiety or depression symptoms were randomly assigned into three groups: (A) music, (B) alpha-theta training, and (C) control. In intervention groups, participants received ten 30-minute sessions of either music or alpha-theta NFT. The Hospital Anxiety and Depression Scale (HADS) was administered for all patients before and after the training period. Thirty-three patients completed the study. Data were analyzed using analysis of covariance (ANCOVA) to compare changes in HADS scores among the three study groups. RESULTS: There was a significant main effect of HADS scores (F1,18 = 17.79, P < 0.001) in the responses of MT group. Significant decreases were observed in HADS scores from pre-intervention to post-intervention tests in MT group comparing to control group. The MT accounted for 49 percent of variance in HADS scores. There was also a significant main effect of HADS scores (F1,20 = 17.79, P < 0.010) in the responses of NFT group. HADS scores from pre-intervention to post-intervention tests in alpha-theta NFT group comparing to control group showed significant decreases, too. In addition, MT and alpha-theta NFT did not show any significant difference in somatic symptoms scores between pretest and posttest among patients with IBS. CONCLUSION: This study showed that MT and alpha-theta NFT significantly alleviated anxiety and depression level among patients with IBS

modeling potential habitats for pergularia tomentosa using maximum entropy model and effect of environmental variables on its quantitative characteristics in arid rangelands southeastern iran

Predicting the potential habitat of plants in arid regions, especially for medicinal ones, is very important. Although Pergularia tomentosa is a key species for medicinal purposes, it appears in very low density in the arid rangelands of Iran, needing an urgent ecological attention. In this study, we modeled and predicted the potential habitat of P. tomentosa using maximum entropy, and the effects of environmental factors (geology, geomorphology, altitude, and soil properties) on some characteristics of the species were determined. The results showed that P. tomentosa was absent in igneous formation while it appeared in conglomerate formation. In addition, among geomorphological units, the best quantitative characteristics of P. tomentosa was belonged to the conglomerate formation-small hill area (plant aerial parts = 57.63 and root length = 30.68 cm) with the highest electrical conductivity, silt, and CaCO3 content. Conversely, the species was not found in the mountainous area with igneous formation. Moreover, plant density, length of roots, and aerial parts of the species were negatively correlated with soil sand, while positive correlation was observed with CaCO3, EC, potassium, and silt content. The maximum entropy was found to be a reliable method (ROC = 0.91) for predicting suitable habitats for P. tomentosa. These results suggest that in evaluating the plant's habitat suitability in arid regions, contrary to the importance of the topography, some environmental variables such as geomorphology and geology can play the main role in rangeland plants' habitat suitability

Comparison of Religious Cognitive Behavioral Therapy, Cognitive Behavioral Therapy, and Citalopram on Depression and Anxiety among Women with Breast Cancer: A Study Protocol for a Randomized Controlled Trial

There has been evidence supporting the reduction of depression and anxiety by religious psychotherapy in cancer patients,however, there have been scarce randomized controlled trials. Therefore, there is a need for replication in a well-designedstudy to investigate the efficacy of these interventions among depressed women with breast cancer. A randomizedcontrolled trial is designed to be conducted on 160 women with breast cancer. Participants will be screened for anxietyand depression diagnosed by clinical interview based on the DSM-IV criteria and the Hospital Anxiety Depression Scale.Golriz and Baraheni’s Religious Attitude Questionnaire will be used to assess the religious attitude. Individuals meetingthe prerequisites will be randomly allocated to four groups, each containing 40 participants, including three interventiongroups (RCBT, CBT, and citalopram) and one control group (usual breast cancer treatment). An instrument by theEORTCQLQ-C30 and BR-23 will be used to measure the quality of life. Blood tests will be taken to assess biomarkers withthe (ELISA) method. The results will determine whether RCBT is more effective than other treatments. If so, the outcomesof the study will have implications not only for the management of similar problems in cancer patients but also for themanagement of other chronic diseases

Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study

Background. Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. Psychological stress can exacerbate the disease. This study sought to investigate the depression and anxiety disorders among patients with psoriasis and control group. Method. In this hospital-based case-control study, One hundred patients with psoriasis (case) referred to the dermatology department and 100 patients with otolaryngology problems and dermatological healthy volunteers (control) who referred to the Otolaryngology Department of Bouali Sina Hospital in Sari, Iran, in 2007 were studied. Demographic characteristics were recorded. Beck Depression Inventory and Spielberger State-Trait Anxiety Scale I-II were administered to the patients in both groups. Data were analyzed using SPSS statistical software and descriptive statistical tests. Results. From One-hundred patients in each group, 44 (45%) were men. Depression score was 67% and 12% in psoriatic patients and control, respectively. The Beck depression scores of patients with psoriasis were significantly higher than scores of the control group (<0.05). Based on Spielberger State-Trait Anxiety Scale, anxiety was found in 45% of patients in case group and 18% of controls. Conclusion. The results revealed that psoriatic patients reported significantly higher degrees of depression and anxiety than controls. In addition, psoriatic women were more depressed than psoriatic men

Social phobia following maprotiline: the first case report

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Adjusted prognostic association of post-myocardial infarction depression withmortality and cardiovascular events: an individual patient data meta-analysis

Background: The association between depression after myocardial infarction (post-MI) and increased risk of mortality and cardiac morbidity may be due to cardiac disease severity. Aims: To combine original data from studies on the association between post-MI depression and prognosis into one database. To investigate to what extent post-MI depression predicts prognosis independently of disease severity. Method: Individual patient data meta-analysis of studies, using multilevel, multivariable Cox regression analyses. Results:Sixteen studies participated, creating a database of 10,175 post-MI patients. HRs for post-MI depression were 1.32 (95%CI 1.26-1.38, p Conclusions: The association between post-MI depression and prognosis is attenuated after adjustment for cardiac disease severity. Still, depression remains independently associated with prognosis, with a 22% increased risk of all-cause mortality and a 13% increased risk of cardiovascular events per standard deviation in depression z-score. Declaration of interest: None